Photoelectric synaptic devices could emulate synaptic behaviors utilizing photoelectric effects and offer promising prospects with their high-speed operation and low crosstalk. In this study, we introduced a novel InG...Photoelectric synaptic devices could emulate synaptic behaviors utilizing photoelectric effects and offer promising prospects with their high-speed operation and low crosstalk. In this study, we introduced a novel InGaZnO-based photoelectric memristor. Under both electrical and optical stimulation, the device successfully emulated synaptic characteristics including excitatory postsynaptic current (EPSC), paired-pulse facilitation (PPF), long-term potentiation (LTP), and long-term depression (LTD). Furthermore, we demonstrated the practical application of our synaptic devices through the recognition of handwritten digits. The devices have successfully shown their ability to modulate synaptic weights effectively through light pulse stimulation, resulting in a recognition accuracy of up to 93.4%. The results illustrated the potential of IGZO-based memristors in neuromorphic computing, particularly their ability to simulate synaptic functionalities and contribute to image recognition tasks.展开更多
目的比较内镜逆行胰胆管造影术(ERCP)与腹腔镜胆总管探查术(LCBDE)对胆囊切除后胆总管结石的临床治疗效果分析。方法回顾性分析2019年10月至2022年10月本院及嘉兴市第一医院收治的59例胆囊切除后胆总管结石病人,分析临床资料及随访资料...目的比较内镜逆行胰胆管造影术(ERCP)与腹腔镜胆总管探查术(LCBDE)对胆囊切除后胆总管结石的临床治疗效果分析。方法回顾性分析2019年10月至2022年10月本院及嘉兴市第一医院收治的59例胆囊切除后胆总管结石病人,分析临床资料及随访资料,按照手术方式分为ERCP组(31例)与LCBDE组(28例),比较两组一般情况、手术相关指标以及术后相关指标等。结果两组一般情况的差异无统计学意义。与LCBDE组相比,ERCP组手术时间更短(85.79±12.69 min vs.106.49±17.81 min),(t=19.154,P<0.001),术中出血量更少(49.98±14.74 mL vs.104.21±20.56 mL),(t=27.538,P<0.001),腹腔粘连发生率等低(25.81%vs.60.71%),(χ^(2)=41.369,P<0.001),引流管使用率更低(64.52%vs.100.00%),(χ^(2)=63.459,P<0.001),ERCP组12.90%(4/28,例)患者复发胆总管结石,ERCP组患者的结石复发率高于LCBDE组(χ^(2)=13.984,P=0.028),两组患者手术成功率、手术失败率以及结石残留率无显著差异(P>0.05)。两组患者肛门排气时间、术后3天GOT、GPT、淀粉酶水平以及术后并发症发生率无显著差异(P>0.05)。ERCP组患者的住院时间短于LCBDE组(11.69±4.25 vs.18.45±5.02),(t=16.324,P<0.001)。结论两种手术皆可有效治疗胆囊切除术后胆总管结石,ERCP更适合基础病多、高龄、不能耐受长时间手术的病人,并且住院时间较短,经济性较高,结石复发可能高于LCBDE;LCBDE适合年轻、无复杂腹腔粘连情况、可以耐受长时间手术的病人,结石复发率优于ERCP。胆囊切除术后腹腔内组织粘连,阻碍了胆总管及术野的显露,导致LCBDE手术失败,而ERCP失败原因是结石直径较大伴嵌顿。展开更多
基金supported by the National Key Research and Development Program of China (2021YFA1202600)the NSFC (92064009, 22175042)+3 种基金the Science and Technology Commission of Shanghai Municipality (22501100900)the China Postdoctoral Science Foundation (2022TQ0068, 2023M740644)the Shanghai Sailing Program (23YF1402200, 23YF1402400)the Qilu Young Scholar Program of Shandong University。
文摘Photoelectric synaptic devices could emulate synaptic behaviors utilizing photoelectric effects and offer promising prospects with their high-speed operation and low crosstalk. In this study, we introduced a novel InGaZnO-based photoelectric memristor. Under both electrical and optical stimulation, the device successfully emulated synaptic characteristics including excitatory postsynaptic current (EPSC), paired-pulse facilitation (PPF), long-term potentiation (LTP), and long-term depression (LTD). Furthermore, we demonstrated the practical application of our synaptic devices through the recognition of handwritten digits. The devices have successfully shown their ability to modulate synaptic weights effectively through light pulse stimulation, resulting in a recognition accuracy of up to 93.4%. The results illustrated the potential of IGZO-based memristors in neuromorphic computing, particularly their ability to simulate synaptic functionalities and contribute to image recognition tasks.
文摘目的比较内镜逆行胰胆管造影术(ERCP)与腹腔镜胆总管探查术(LCBDE)对胆囊切除后胆总管结石的临床治疗效果分析。方法回顾性分析2019年10月至2022年10月本院及嘉兴市第一医院收治的59例胆囊切除后胆总管结石病人,分析临床资料及随访资料,按照手术方式分为ERCP组(31例)与LCBDE组(28例),比较两组一般情况、手术相关指标以及术后相关指标等。结果两组一般情况的差异无统计学意义。与LCBDE组相比,ERCP组手术时间更短(85.79±12.69 min vs.106.49±17.81 min),(t=19.154,P<0.001),术中出血量更少(49.98±14.74 mL vs.104.21±20.56 mL),(t=27.538,P<0.001),腹腔粘连发生率等低(25.81%vs.60.71%),(χ^(2)=41.369,P<0.001),引流管使用率更低(64.52%vs.100.00%),(χ^(2)=63.459,P<0.001),ERCP组12.90%(4/28,例)患者复发胆总管结石,ERCP组患者的结石复发率高于LCBDE组(χ^(2)=13.984,P=0.028),两组患者手术成功率、手术失败率以及结石残留率无显著差异(P>0.05)。两组患者肛门排气时间、术后3天GOT、GPT、淀粉酶水平以及术后并发症发生率无显著差异(P>0.05)。ERCP组患者的住院时间短于LCBDE组(11.69±4.25 vs.18.45±5.02),(t=16.324,P<0.001)。结论两种手术皆可有效治疗胆囊切除术后胆总管结石,ERCP更适合基础病多、高龄、不能耐受长时间手术的病人,并且住院时间较短,经济性较高,结石复发可能高于LCBDE;LCBDE适合年轻、无复杂腹腔粘连情况、可以耐受长时间手术的病人,结石复发率优于ERCP。胆囊切除术后腹腔内组织粘连,阻碍了胆总管及术野的显露,导致LCBDE手术失败,而ERCP失败原因是结石直径较大伴嵌顿。
