Objective To analyze the effect of the numbers of transferred good-quality embryos on pregnancy outcomes in in vitro fertilization-embryo transfer （IVF-ET）, supplying a reference for selection of transferred embryos...Objective To analyze the effect of the numbers of transferred good-quality embryos on pregnancy outcomes in in vitro fertilization-embryo transfer （IVF-ET）, supplying a reference for selection of transferred embryos.Methods Five hundreds and one infertile patients who underwent IVF-ET were retrospectively analyzed. All cycles were divided into 3 groups by the number of transferred good-quality embryos （group A： two good-quality embryos, group B： one good-quality embryo, group C： no good-quality embryo）, with no significant difference in general condition such as age, infertility duration and infertility types. The pregnancy outcomes were compared and analyzed among the three groups.Results 1） Live-birth rate was improved with increasing good-quality transferred embryo numbers. Groups A （70.3%） and B （69.8%） had no significant difference （P=0. 409）, whereas it was significantly greater in groups A and B than in group C （57. 7%） （P=0.009, P=0.036）. 2） The loss of single gestational sacs rate, which have no significant difference among 3 groups （P=0.221, P=0.539, P=0.226）, reduced with increasing good-quality transferred embryos numbers. 3） Biochemical pregnancy abortion rate in groups A （10.9%） and B （10.1%） was significantly lower than that in group C （18.3%）（P=0.049, P=0.049）. 4） There was no significant difference among 3 groups in ectopic pregnancy rate （P=0.174, P=0.129, P=0.404）. 5）Multiple-birth rate was improved with increasing good-quality transferred embryos numbers, it was significantly greater in group A （31.6%） than in group C （15.0%）（P=0.020）, while groups B and A had no significant difference （P=0.489, P=0.126）.Conclusion Two good-quality transferred embryos have no significantly difference to 1 good-quality embryo in all pregnancy outcomes. In clinic treatment, we can select 1 good-quality embryo and 1 poor-quality embryo when patients only have few goodquality embryos. Meanwhile, a good-quality embryo can improve live-birth rate and multiple pregnancy rate simultaneously. In order to meet a better assisted reproductive technology （ART） outcome, we need to seek a balance between pregnancy rate and multiple pregnancy rate.展开更多
文摘Objective To analyze the effect of the numbers of transferred good-quality embryos on pregnancy outcomes in in vitro fertilization-embryo transfer （IVF-ET）, supplying a reference for selection of transferred embryos.Methods Five hundreds and one infertile patients who underwent IVF-ET were retrospectively analyzed. All cycles were divided into 3 groups by the number of transferred good-quality embryos （group A： two good-quality embryos, group B： one good-quality embryo, group C： no good-quality embryo）, with no significant difference in general condition such as age, infertility duration and infertility types. The pregnancy outcomes were compared and analyzed among the three groups.Results 1） Live-birth rate was improved with increasing good-quality transferred embryo numbers. Groups A （70.3%） and B （69.8%） had no significant difference （P=0. 409）, whereas it was significantly greater in groups A and B than in group C （57. 7%） （P=0.009, P=0.036）. 2） The loss of single gestational sacs rate, which have no significant difference among 3 groups （P=0.221, P=0.539, P=0.226）, reduced with increasing good-quality transferred embryos numbers. 3） Biochemical pregnancy abortion rate in groups A （10.9%） and B （10.1%） was significantly lower than that in group C （18.3%）（P=0.049, P=0.049）. 4） There was no significant difference among 3 groups in ectopic pregnancy rate （P=0.174, P=0.129, P=0.404）. 5）Multiple-birth rate was improved with increasing good-quality transferred embryos numbers, it was significantly greater in group A （31.6%） than in group C （15.0%）（P=0.020）, while groups B and A had no significant difference （P=0.489, P=0.126）.Conclusion Two good-quality transferred embryos have no significantly difference to 1 good-quality embryo in all pregnancy outcomes. In clinic treatment, we can select 1 good-quality embryo and 1 poor-quality embryo when patients only have few goodquality embryos. Meanwhile, a good-quality embryo can improve live-birth rate and multiple pregnancy rate simultaneously. In order to meet a better assisted reproductive technology （ART） outcome, we need to seek a balance between pregnancy rate and multiple pregnancy rate.
