Shortly after birth, a five-week-old female infant developed smal l bliste rs and erythema that followed the lines of Blaschko on the upper and lower extre mities as well as the abdomen. Histological examination confi...Shortly after birth, a five-week-old female infant developed smal l bliste rs and erythema that followed the lines of Blaschko on the upper and lower extre mities as well as the abdomen. Histological examination confirmed the clinical p resumptive diagnosis of incontinentia pigmenti. We discuss the clinical features , diagnosis, and the molecular genetic basis of this rare inherited skin disorde r.展开更多
A9-year-old female developed facial papules and pustules since fo ur years . Clinically, perioral dermatitis was suspected. Different topical therapy regim ens and systemic antibiotics had been unsuccessful and a skin...A9-year-old female developed facial papules and pustules since fo ur years . Clinically, perioral dermatitis was suspected. Different topical therapy regim ens and systemic antibiotics had been unsuccessful and a skin biopsy showed gran ulomatous (lupoid) rosacea. Only systemic antibiotic treatment with minocyclin l ed to healing of the skin lesions. While granulomatous rosacea-like dermatitis is more frequently diagnosed in adults, it is only rarely encountered in childr en where, in most of the cases, it represents a therapeutic challenge.展开更多
文摘Shortly after birth, a five-week-old female infant developed smal l bliste rs and erythema that followed the lines of Blaschko on the upper and lower extre mities as well as the abdomen. Histological examination confirmed the clinical p resumptive diagnosis of incontinentia pigmenti. We discuss the clinical features , diagnosis, and the molecular genetic basis of this rare inherited skin disorde r.
文摘A9-year-old female developed facial papules and pustules since fo ur years . Clinically, perioral dermatitis was suspected. Different topical therapy regim ens and systemic antibiotics had been unsuccessful and a skin biopsy showed gran ulomatous (lupoid) rosacea. Only systemic antibiotic treatment with minocyclin l ed to healing of the skin lesions. While granulomatous rosacea-like dermatitis is more frequently diagnosed in adults, it is only rarely encountered in childr en where, in most of the cases, it represents a therapeutic challenge.
