Microalgae are unicellular photosynthetic organisms that have been recently attracted potential interests and have applications in food,nutraceuticals,pharmaceuticals,animal feed,cosmetics,and biofertilizers industry....Microalgae are unicellular photosynthetic organisms that have been recently attracted potential interests and have applications in food,nutraceuticals,pharmaceuticals,animal feed,cosmetics,and biofertilizers industry.Microalgae are rich in a variety of high-value bioactive compounds which have potential benefits on human health and can be used for the prevention and curing of many disease conditions.But scale-up and safety issues remain a major challenge in the commercialization of microalgal products in a cost-effective manner.However,techniques have been developed to overcome these challenges and successfully selling the products derived from microalgae as food,cosmetics and pharmaceutical industries.Microalgae are rich in many nutrients and can be used for the production of functional food and nutraceuticals,safety and regulatory issues are major concerns and extensive research is still needed to make microalgae a commercial success in the future.Many practical difficulties are involved in making the microalgal food industry commercially viable.The present review focuses on the industrial applications of microalgae and the challenges faced during commercial production.展开更多
Microalgae are considered a rich source of high-value metabolites with an array of nutraceutical and pharmaceutical applications.Diferent strategies have been developed for cultivating microalgae at large-scale photob...Microalgae are considered a rich source of high-value metabolites with an array of nutraceutical and pharmaceutical applications.Diferent strategies have been developed for cultivating microalgae at large-scale photobioreactors but high cost and low productivity are the major hurdles.Optimizing the composition of media for the cultivation of microalgae to induce biomass production and high-value metabolite accumulation has been considered as an important factor for sustainable product development.In this study,the efect of plant growth regulators together with basal microalgal cultivation medium on biomass,total lipid,and EPA production was studied using the Plackett–Burman model and Response surface methodology.The traditional one-factor-at-a-time optimization approach is laborious,time-consuming,and requires more experiments which makes the process and analysis more difcult.The Designed PB model was found to be signifcant for biomass(396 mg/L),lipid(254 mg/L),and EPA(5.6%)production with a P value<0.05.The major objective of this study is to formulate a medium for EPA production without compromising the growth properties.Further,we had formulated a new media using RSM to achieve the goal and the signifcant variables selected were NaNO_(3),NaH_(2)PO_(4),and IAA and was found to be signifcant with 16.72%EPA production with a biomass production of 893 mg/L with a P value<0.05.The formulated medium can be used in large-scale cultivation systems which can enhance biomass production as well as the omega 3 fatty acid production in marine microalgae Nannochloropsis oceanica.展开更多
文摘Microalgae are unicellular photosynthetic organisms that have been recently attracted potential interests and have applications in food,nutraceuticals,pharmaceuticals,animal feed,cosmetics,and biofertilizers industry.Microalgae are rich in a variety of high-value bioactive compounds which have potential benefits on human health and can be used for the prevention and curing of many disease conditions.But scale-up and safety issues remain a major challenge in the commercialization of microalgal products in a cost-effective manner.However,techniques have been developed to overcome these challenges and successfully selling the products derived from microalgae as food,cosmetics and pharmaceutical industries.Microalgae are rich in many nutrients and can be used for the production of functional food and nutraceuticals,safety and regulatory issues are major concerns and extensive research is still needed to make microalgae a commercial success in the future.Many practical difficulties are involved in making the microalgal food industry commercially viable.The present review focuses on the industrial applications of microalgae and the challenges faced during commercial production.
基金The work was supported by the grant from the Department of Science and Technology-SERB,Government of India through the Core Research Grant Project“CRG/2019/001913:Investigation on identifcation and biochemical validation of selenoproteins from Nannochloropsis oceanica CASA CC201 as functional food/feed supplements”to MA.We are thankful for the fnancial support from DST-INSPIRE fellowship of Department of Science and Technology,New Delhi for doctoral studies of AU.
文摘Microalgae are considered a rich source of high-value metabolites with an array of nutraceutical and pharmaceutical applications.Diferent strategies have been developed for cultivating microalgae at large-scale photobioreactors but high cost and low productivity are the major hurdles.Optimizing the composition of media for the cultivation of microalgae to induce biomass production and high-value metabolite accumulation has been considered as an important factor for sustainable product development.In this study,the efect of plant growth regulators together with basal microalgal cultivation medium on biomass,total lipid,and EPA production was studied using the Plackett–Burman model and Response surface methodology.The traditional one-factor-at-a-time optimization approach is laborious,time-consuming,and requires more experiments which makes the process and analysis more difcult.The Designed PB model was found to be signifcant for biomass(396 mg/L),lipid(254 mg/L),and EPA(5.6%)production with a P value<0.05.The major objective of this study is to formulate a medium for EPA production without compromising the growth properties.Further,we had formulated a new media using RSM to achieve the goal and the signifcant variables selected were NaNO_(3),NaH_(2)PO_(4),and IAA and was found to be signifcant with 16.72%EPA production with a biomass production of 893 mg/L with a P value<0.05.The formulated medium can be used in large-scale cultivation systems which can enhance biomass production as well as the omega 3 fatty acid production in marine microalgae Nannochloropsis oceanica.
