Current Status of Traditional Chinese and Western Medicine Treatment of Diabetic Peripheral Vascular Disease

Diabetic peripheral vascular disease(PVD)is one of the common chronic complications of diabetes.The main clinical manifestations of PVD are numbness and coldness of the limbs,resting pain,intermittent claudication,and other symptoms.The combined treatment involving Chinese and Western medicine for PVD has various clinical methods and definite curative effects.It is worthy of in-depth clinical research and application.

Clinical Experience in the Treatment of Vulvovaginal Candida Disease with Integrated Traditional Chinese and Western Medicine

Summarizing two cases of vaginal candidiasis,cured by integrated traditional Chinese and western medicine in clinical work,it is found that the combination of traditional Chinese and western medicine has a significant effect on the treatment of this disease.The curative effect is outstanding,and the recurrence rate is significantly reduced,which can be used as a reference for gynecological medical workers.

Research Progress of Non-drug Therapy of Traditional Chinese Medicine in the Treatment of Obese Polycystic Ovary Syndrome

Polycystic ovarian syndrome(PCOS)as a relatively common clinical reproductive endocrine disease,the incidence is increasing year by year and the treatment is difficult,among which obese PCOS accounts for nearly 50%of the total.In recent years,non-drug therapy of traditional Chinese medicine(TCM)has been effective in the treatment of PCOS.This article summarizes the relevant literature in the past ten years from acupuncture,acupoint embedding,moxibustion,and auricular points,and observes the effects of TCM non-drug therapy on endocrine and glucose and lipid metabolism in obese PCOS patients.The impact of various indicators such as body mass index,body mass index,etc.,and discuss the problems in such treatments,as well as put forward suggestions to achieve the purpose of better guiding the clinical treatment of obese PCOS.

Understanding of Dry Eye Syndrome in Traditional Chinese Medicine

Explore the current status of Chinese medicine understanding and prevention and treatment of dry eye,so as to improve the efficacy of Chinese medicine in the diagnosis and treatment of dry eye.

Research Progress of Traditional Chinese Medicine in Treating Dysphagia After Stroke

Dysphagia is a common complication after stroke,which does not only affect the quality of life of patients,but also increase the risk of death.Traditional Chinese medicine(TCM)treatment has always played an important role in the clinical treatment of dysphagia after stroke,but its mechanism has not been fully elucidated.Literatures on the use of TCM for the disease in the recent 5 years have been reviewed,and the problems existing in the development and treatment of the disease are discussed in this article,in an attempt to provide new ideas for the treatment of the disease.This paper presents a summary of traditional Chinese medicine treatment for the disease in the past five years,including traditional Chinese medicine compound and acupuncture.

Study on Prevention and Treatment of Autophagy and Cervical HPV Infection by Traditional Chinese Medicine Based on Pathogenesis of "Syndrome of Dampness-heat Diffusing Downward"

Autophagy is a self-protection mechanism of the body,and also an important physiological process for cells to maintain internal environment stability.Studies have shown that the degree of autophagy damage is positively correlated with the expression of oncogenes,and the expression of oncogenes is closely related to cervical HPV infection,so the control of autophagy ability can interfere with cervical HPV virus infection.Traditional Chinese medicine believes that dampness-heat evil down,can damage and Chong Ren cell.The author believes that autophagy damage and the theory of dampness-heat injection in cervical HPV infection have similar pathogenic mechanism,and explores the prevention and treatment of autophagy and cervical HPV infection based on the theory of traditional Chinese medicine dampness-heat injection,in attempt to provide a new treatment for clinical prevention and treatment.

Research Progress of Treating Diabetic Nephropathy with Traditional Chinese Medicine

By collecting and sorting out the literature and journals on the clinical use of Chinese medicine in the treatment of diabetic nephropathy in recent years,it is concluded that Chinese medicine is effective in the treatment of DKD.Chinese medicine therapy has a unique role in the treatment of diabetic nephropathy.How to correct syndrome differentiation and treatment?Improving clinical effects is the research direction that all medical staff will work together in the future.

Research Progress of Combination of Traditional Chinese and Western Medicine in Treatment of Infertility in Older Women

The main cause of infertility in elderly women is poor ovarian function,decreased quality and number of oocytes,which ultimately leads to poor fertility.Low ovarian function is the most difficult point in the research of reproductive medicine and reproductive health.At present,the treatment of integrated traditional Chinese and Western medicine has gradually achieved results.Western medicine mainly regulates endocrine and assisted reproductive treatment by supplementing estrogen and progesterone,while traditional Chinese medicine(TCM)mainly focuses on invigorating the kidney,adding and subtracting according to the syndrome.The treatment effect of TCM or western medicine alone is not significant.Many clinical observations show that integrated TCM and western medicine focuses on the specialties of western medicine,which not only makes up for the insufficiency of the slow action of TCM,but also improves its clinical efficacy when combined with western medicine.Based on domestic and foreign research,this article summarizes the treatment of infertility in elderly women with integrated TCM and western medicine.

Study on the medication rule of herbs for uterine bleeding in ancient Chinese medicine

To explore the rule of medication in metrorrhagia treatment in ancient China.Based on the electronic publication“Chinese Medical Dictionary”,collect relevant literature on the treatment of metrorrhagia metrostaxis by various physicians in the Ming and Qing Dynasties(1368 C.E.–1644 C.E.),extract the effective prescriptions for the treatment of metrorrhagia metrostaxis,and evaluate the frequency of cluster statistical analysis including its effect,flavor and meridian tropism.A total of 199 prescriptions about metrorrhagia and 196 traditional Chinese medicines were included.The results shed light on how ancient Chinese doctors used herbs.During the Ming and Qing Dynasties,people recognized the pathogenesis of uterine bleeding and classified it using traditional Chinese medicine theories.Different herbs are given to different patients according to their clinical characteristics.This paper explains the classification of medicines in ancient China in English.A corresponding botanical name was used for each herb.

A Brief Analysis on the Characteristics of Chinese Medicine and Treatment for Cough Variant

Cough variant is a common disease of the respiratory system and can lead to a unique type of asthma.The disease has no obvious symptoms such as wheezing nor shortness of breath.Coughing is the main clinical symptom,as it causes airway hyper-responsiveness.Traditional Chinese medicine(TCM)has a unique understanding of this disease,and the effect is obvious after treatment,as it's based on symptom differentiation.This article takes the concept of“mild fluid retention”from“The Synopsis of the Golden Chamber”as an entry point,briefly describes the relationship between cough variant and mild fluid retention,as well as the diagnosis and treatment of Chinese medicine.

Research progress of modern pharmacological effects of Pueraria lobata and its compound clinical application

As a traditional Chinese medicine, Pueraria lobata has been widely recorded in Chinese herbal works of the past dynasties. Modern studies have found that its main chemical components are isoflavones, triterpenoids, saponins, etc., which have antipyretic, anti⁃inflammatory, anti⁃infection, blood pressure, blood sugar, blood lipid, and pharmacological effects such as improving reproductive function. Clinically, it is used in the treatment of diabetic diseases, gastrointestinal diseases, cardiovascular diseases, etc. in the form of traditional Chinese medicine compound prescriptions. This reseach aims to summarize related articles of Pueraria lobata in the past 5 years, focusing on its pharmacological effects and clinical application of the compound, and provide references for its further development and utilization.

Polycystic Ovary Syndrome-Related Infertility Based on the Theory of“Liver and Kidney Homology”

Polycystic ovary syndrome(PCOS)is an endocrine disorder caused by hypothalamic-pituitary-ovarian(HPO)axis dysfunction.In the field of gynecology and reproduction,PCOS has emerged as both a research hot spot and a challenging area of study.According to Chinese medicine,this disease is related to kidney deficiency,phlegm and dampness obstruction,blood stasis and interconnection,Chong pulse impassability,the lack of Ren pulse,and the loss of uterine nourishment,all of which affect the normal development and maturation of eggs as well as the duration at which menstrual blood stores.In this paper,based on the theoretical basis of“liver collects blood,regulates the flow of qi,and is the master of drainage,”we explore the rationality of the treatment of this disease from the perspective of“liver and kidney have the same origin”and the development of PCOS-related infertility in relation to dysfunctional internal organs.We also explore the feasibility of treatment from the perspective of“liver and kidney homology,”expand the ideas for treatment,as well as develop and innovate the application of organ identification in PCOS in relation to infertility.

A Review on Clinical Study on Treating Postoperative Constipation in Mixed Hemorrhoids with Traditional Chinese Medicine

Mixed hemorrhoids belong to a common disease in proctology.Surgery is the main clinical treatment,but postoperative constipation is prone to occur in patients,causing unnecessary physical pain to the patients.At the same time,it also affected uneventful recovery after the surgery.In diagnosis and treatment for the postoperative constipation in mixed hemorrhoids,TCM has its own features,such as oral administration of Chinese materia medica,acupuncture therapy,Chinese materia medica retention enema,acupoint catgut embedding,etc.,which have significant efficacy.However,there are also some problems,such as inconsistency of clinical syndrome differentiation,lack of large sample studies,and insufficient follow-up visits.In order to provide reference for clinical treatment in mixed hemorrhoids,this paper reviews academic studies on its postoperative constipation by traditional Chinese medicine in recent years.

Effect of curcumin on expressions of NF-κBp65,TNF-αand IL-8 in placental tissue of premature birth of infected mice

Objective:To observe the effect of curcumin on expressions of nuclear transcription factorkappa Bp65(NF-κBp65),TNF--α and IL-8 in placental tissue of premature birth of infected mice induced by lipopolysaccharide(LPS).Methods:A total of 60 C57BL/6 mice pregnant with 15 d were collected and randomly divided into control group,model group,treatment group and preventative group.LPS was repeatedly injected in abdominal cavity to construct infected premature birth model,while mice of control group were given with 100 mg/kg of vitamin C through abdominal cavity injection and mice of treatment group and preventative group were given curcumin of 100 mg/kg through abdominal cavity injection after modeling operation and before 1 d of modeling operation,respectively.A total of 5 mice of four groups respectively were executed by cervical dislocation after 6 h,12 h and 24 h after constructing model.Placental tissues were collected and the immunohistochemical mothod SABC of immunologic tissue was used to detect the expression of NF-d mice after 24 h was collected tκBp65,TNF-o detect the co-and IL-8 and peripheral blood of executencentrations of IL-8,malondialdehyde(MDA) and superoxide dismutase(SOD),meanwhile live birth rate of four groups was contrasted.Results:Staining intensity of NF-tissue of treatment group and preventative group was κBp65,TNF-significantly-αand IL-8 in placental higher than control group but lower than model group(P<0.05).Level of serum IL-8 and MDA of control group was significantly lower than the other three groups(P<0.05) and level of blood of SOD in model group was significantly lower than control group(P<0.05).Levels of serum IL-8 and MDA of treatment group and preventative group were significantly lower than model group(P<0.05) while level of SOD was significantly higher than model group(P<0.05).Live birth rate of treatment group and preventative group was significantly higher than model group(P<0.05).Conclusions:Curcumin can effectively prevent the active pathway of NF-t tissue of premature birth of infected mice,reduce the expression of TNF-κB in pregnanieve the damage of lipid peroxide of oxidative stress of LPS on mother-fetus-α and IL-8 and rel and further to achieve the objective of preventing and curing premature birth induced with infection.

Quantitative computed tomography analysis for stratifying the severity of Coronavirus Disease 2019

To examine the feasibility of using a computer tool for stratifying the severity of Coronavirus Disease 2019(COVID-19)based on computed tomography(CT)images.We retrospectively examined 44 confirmed COVID-19 cases.All cases were evaluated separately by radiologists(visually)and through an in-house computer software.The degree of lesions was visually scored by the radiologist,as follows,for each of the 5 lung lobes:0,no lesion present;1,<1/3 involvement;2,>1/3 and<2/3 involvement;and 3,>2/3 involvement.Lesion density was assessed based on the proportion of ground-glass opacity(GGO),consolidation and fibrosis of the lesions.The parameters obtained using the computer tool included lung volume(mL),lesion volume(mL),lesion percentage(%),and mean lesion density(HU)of the whole lung,right lung,left lung,and each lobe.The scores obtained by the radiologists and quantitative results generated by the computer software were tested for correlation.A Chi-square test was used to test the consistency of radiologist-and computer-derived lesion percentage in the right/left lung,upper/lower lobe,and each of the 5 lobes.The results showed a strong to moderate correlation between lesion percentage scores obtained by radiologists and the computer software(r ranged from 0.7679 to 0.8373,P<0.05),and a moderate correlation between the proportion of GGO and mean lesion density(r=-0.5894,P<0.05),and proportion of consolidation and mean lesion density(r=0.6282,P<0.05).Computer-aided quantification showed a statistical significant higher lesion percentage for lower lobes than that assessed by the radiologists(x^2=8.160,P=0.004).Our experiments demonstrated that the computer tool could reliably and accurately assess the severity and distribution of pneumonia on CT scans.

Effect of sinomenine stellate ganglion block on chronic myocardial ischemia in rats

Objective:To investigate the protective effect of sinomenine stellate ganglion block(SGB)on chronic myocardial ischemia and its related mechanism.Methods:SD male and female rats(180~200g)were randomly divided into four groups:blank group,model group,lidocaine group,lidocaine+sinomenine group.The rats in blank group were fed with normal standard diet without modeling,and the other rats were fed with high-fat diet.After 8 weeks of feeding,the rats in high-fat diet group were significantly different from those in blank control group.Then they were randomly divided into 3 groups,10 rats in model group were injected with 0.9%NaCl into right stellate ganglion(RSG)After 2 weeks of continuous injection,pituitrin injection was continuously injected into sublingual vein of rats for 3 days,once every 24 hours;lidocaine group rats were injected with 0.24 mL 1%lidocaine injection in RSG,the rest was the same as model group;lidocaine+sinomenine group rats were injected with 0.24 mL 1%lidocaine injection+0.095 mL sinomenine hydrochloride+2.9 mL 0.8 mL 0.8 mL in RSG,the rest was the same as model group.At the end of the eighth week of the experiment,the rats in the high-fat diet feeding group and the standard ordinary diet feeding group were given the medicine after there was significant difference in blood lipid;before the third injection of pituitrin,the ECG changes of the rats in each group were observed;the general situation of the rats before and after the administration was observed;after the experiment,the blood of the rats in each group was taken from the abdominal aorta,and the serum oxidative stress indexes,such as total superoxide dismutase(SOD)and malondialdehyde,were detected(MDA,IL-6 and cTnI were measured.Results:compared with the blank group,the ECG of the model group changed significantly(P<0.01),the cTnI value increased significantly(P<0.01),indicating that the rat myocardial ischemia model was successfully established;compared with the model group,the SOD level of lidocaine group and lidocaine+sinomenine group increased significantly(P<0.05,P<0.01),the MDA level decreased significantly(P<0.05,P<0.01),IL-6 decreased significantly(P<0.05,P<0.01)05,P<0.01).Conclusion:sinomenine SGB has protective effect on rats with chronic myocardial ischemia,which is related to anti oxidative stress and inhibition of inflammatory reaction.

Moxibustion plus acupuncture improves the efficacy and quality of life of patients with polycystic ovary syndrome: A randomized controlled trial

Objective:To observe the effect of moxibustion combined with acupuncture on the efficacy and quality of life of spleen-kidney-yang-deficiency patients with polycystic ovary syndrome(PCOS).Materials and Methods:A total of 90 patients with PCOS of spleen-kidney yang deficiency type from January 2020 to March 2021 were selected and randomly divided into three groups,30 patients each in the moxibustion group,acupuncture group,and moxibustion combined with acupuncture group(combined group).The changes of body mass index(BMI),waist-to-hip ratio(WHR),fasting insulin(FINS),fasting plasma glucose(FPG),homeostasis model assessment-insulin resistance index(HOMA-IR),follicle-stimulating hormone(FSH),luteinizing hormone(LH),testosterone(T),triglycerides(TG),total cholesterol(TC),traditional Chinese medicine(TCM)clinical symptom score,efficacy,and quality of life score in the three groups were observed before and 3 months after treatment.Results:After treatment,(1)compared with the moxibustion and acupuncture groups,the combined group was more effective in reducing BMI(F=5.274,P<0.05)and WHR(F=8.246,P<0.05)in PCOS patients;(2)FINS,FPG,and HOMA-IR were reduced in all three groups,and the reduction in these three indicators was more pronounced in combined group(FINS:F=5.637,P<0.05,FPG:F=4.915,P<0.05,HOMA-IR:F=3.817,P<0.05);(3)The FSH,LH,and T levels of patients in the combined group were better than those in the remaining two groups(FSH:F=4,163,P<0.05,LH:F=5.098,P<0.05,T:F=7.038,P<0.05);(4)The TG and TC of patients in the combined group were lower than those in the remaining two groups(TG:F=4.806,P<0.05,TC:F=3.828,P<0.05);(5)The TCM clinical symptom score of the combined group was significantly lower than those of the moxibustion and acupuncture groups(F=4.547,P<0.05);(6)The quality of life of patients in the combined group improved more significantly than the moxibustion and acupuncture groups(F=6.239,P<0.05);(7)The total effective rate of the combined group was higher than that of the moxibustion and acupuncture groups(χ2=6.947,P=0.031).Conclusion:The combination of moxibustion and acupuncture can effectively reduce the BMI and WHR of PCOS patients,improve the endocrine function,sex hormone level,TCM symptoms and quality of life of patients,and has significant efficacy and high safety,which is worthy of wide clinical application.

Effect of Percutaneous Radiofrequency Ablation and Surgical Resection on Treating of Primary Small Liver Cancer: A Meta-Analysis

Objective:To analyze the clinical effect of primary small liver cancer under radiofrequency ablation(RFA)and surgical resection(SR)treatment,and to explore the best application timing of the two treatment methods.Methods:Randomly controlled clinical trials(RCT)of percutaneous radiofrequency ablation and surgical resection for the treatment of small liver cancer in various databases were searched according to the established search strategy,and Meta data was analyzed based on RevMan5.3 software provided by Cochrane collaborative organization.Results:A total of 10 articles were included in this study,including 1396 patients,699 in the RFA group and 697 in the SR group.Meta-analysis results showed that the two groups had no statistical difference in overall survival rate at 1 and 3 years,1-year disease-free survival rate,and 1-year recurrence rate(P>0.05).The 3-year disease-free survival rate of the RFA group was lower than that of the SR group,and the 3-year recurrence rate was higher than that of the SR group.The higher postoperative complication rate tended to the SR group,and the differences were statistically significant.(P<0.05).Conclusion:For short-term efficacy,radiofrequency ablation and surgical resection show consistency;for long-term efficacy,surgical resection is more effective.

Research Progress of Osteoporosis Based on the Theory of"Homology of Liver and Kidney"

Osteoporosis is a systemic chronic metabolic bone disease,mainly in the elderly and postmenopausal women.At present,most of the clinical treatment is western medicine,but the curative effect is not very significant.In the treatment of osteoporosis,traditional Chinese medicine(TCM)is mainly based on the overall concept of TCM.This article briefly analyzes osteoporosis from the theory of"liver and kidney homology,"discusses the research on osteoporosis in TCM,and hopes to provide reference for the clinical treatment and research of osteoporosis.

Analysis of Famous TCM Doctor Zan Qiang's Experience in the Treatment of Perimenopausal Osteoporosis

The purpose of this study was to analyze the clinical experience of Zan Qiang,a famous doctor of Traditional Chinese Medicine in Shaanxi province,in the treatment of perimenopausal osteoporosis.Zan believed that the main etiology and pathogenesis of perimenopausal osteoporosis were "deficiency of kidney essence,decreased marrow and bone",deficiency of liver and kidney"and"stasis caused by deficiency".Although it is a chronic physiological disease,and the pathological process is irreversible,the treatment groups of"tonifying kidney and filling essence","tonifying liver and tonifying kidney"and "tonifying deficiency and promoting blood circulation" can significantly improve the symptoms of patients,slow down the progress of the disease and improve the quality of life of patients.