Participation, support and understanding of countries along the Belt and Road are requisites for promoting and implementing this major initiative. Indonesia, a major ASEAN economy, is crucial but Indonesia has a limit...Participation, support and understanding of countries along the Belt and Road are requisites for promoting and implementing this major initiative. Indonesia, a major ASEAN economy, is crucial but Indonesia has a limited perception of the B&R initiative. Although its government welcomes it and the ruling coalition cooperates positively, parts of the military and opposition are skeptical of China's intent. The B&R initiative is well-received among the Indonesian Chinese group, while Indonesian academic circles remain cautious and somewhat critical. From a Chinese viewpoint, easing negative or hostile emotions appropriately would be well-timed. China should settle the Natuna issue, adjust its publicity in Indonesia, use diplomacy, and promote Sino-Indonesia cultural exchange and communications. Chinese enterprises should focus on project quality and uphold social responsibilities. Short-term goals are reducing Indonesia's opposition and obstruction of B&R, while long-term goals are enhancing the recognition and likeability of the Initiative's worthwhile plans.展开更多
Introduction Throughout a woman’s life,several unique health characteristics are related to an increased risk of later disease morbidity and/or premature mortality(Fig.1).For instance,these include early age at menar...Introduction Throughout a woman’s life,several unique health characteristics are related to an increased risk of later disease morbidity and/or premature mortality(Fig.1).For instance,these include early age at menarche1,2(ie,“short,irregular or long menstrual cycles”)3,4,a history of infertility5,pregnancy loss6,several major pregnancy complications(eg,preeclampsia,gestational hypertension,gestational diabetes mellitus(GDM)and preterm delivery)7–9,and menopause characteristics(eg,long menopause transition period,early age at menopause,and the presence of vasomotor symptoms).展开更多
Over the past two decades,population-based studies employing semiautomatic computer-assisted programs have uncovered associations between retinal microvascular features and various systemic conditions.As the recogniti...Over the past two decades,population-based studies employing semiautomatic computer-assisted programs have uncovered associations between retinal microvascular features and various systemic conditions.As the recognition of retinal imaging in cardiometabolic health grows,there is increasing evidence supporting its application in women’s health,particularly during the reproductive age.This review aims to summarize the indications of retinal imaging in women’s health and intergenerational health,where suboptimal retinal imaging has been found to mirror pathological systemic changes,such as suboptimal hemodynamic circulation,inflammation,endothelial dysfunction,oxidative stress,and hypoxia in vivo.Findings from Singapore Growing Up in Singapore Towards Healthy Outcomes and Singapore Preconception Study of Long-Term Maternal and Child Outcomes cohorts have reported serial changes in retinal conventional microvascular features(e.g.,retinal arteriolar narrowing,retinal venular widening)and retinal geometric microvascular features(e.g.,sparse fractal dimension,enlarged branching angle,and increased curvature tortuosity)during the preconception and antenatal phases.These morphological abnormalities were found to be related to female fertility,maternal antenatal health conditions,postnatal maternal cardiometabolic health,and intergenerational health in the fetus.Given the compelling evidence of the ability to detect microvascular changes through noninvasive methods at an early stage,retinal imaging holds the potential to facilitate timely interventions,mitigate the progression of complications,and prevent adverse pregnancy outcomes.Looking ahead,the convergence of artificial intelligence and advanced imaging techniques heralds a promising era in women’s health research and clinical practice.展开更多
It is imperative that India and China regain past civilizational glory by showing sensitivity to each other's concerns and reaching goals through cooperation.
The SCO summit aligns with India's worldview of"the world as a family,"as does the China-proposed Global Development Initiative,Global Security Initiative,and Global Civilization Initiative,all of which ...The SCO summit aligns with India's worldview of"the world as a family,"as does the China-proposed Global Development Initiative,Global Security Initiative,and Global Civilization Initiative,all of which mark steps toward a shared future for mankind.The Shanghai Cooperation Organization(SCO)is an important and inclusive organization immune to Cold War baggage.Enjoying observer status at the United Nations General Assembly(UNGA),the SCO has full members,observers,and dialogue partners whose development,geopolitical,and national security interests converge.展开更多
Integrated study of rock assemblage, tectonic setting, geochemical feature, fossil contained and isotopic geochronology on the metamorphic mixed bodies, exposed in the Jinshajiang suture zone, suggests that one inform...Integrated study of rock assemblage, tectonic setting, geochemical feature, fossil contained and isotopic geochronology on the metamorphic mixed bodies, exposed in the Jinshajiang suture zone, suggests that one informal lithostratigraphic unit, the Eaqing Complex, and three tectono-stratigraphic units, the Jinshajiang ophiolitic melange, the Gajinxueshan Group and the Zhongxinrong Group, can be recognized there. It is first pointed out that the redefined Eaqing Complex might represent the Meso- to Neo-Proterozoic remnant metamorphic basement or mi-crocontinental fragment in the Jinshajiang area. The original rocks of it should be older than (1627 ±192) Ma based on the geochronological study. The zircon U-Pb age of plagiogranites within the Jinshajiang ophiolitic assemblage is dated for the first time at (294 ± 3) Ma and (340 ± 3) Ma respectively. The Jinshajiang ophiolite is approximately equivalent to the Ailaoshan ophiolite in the formation age, covering the interval from the Late Devonian to the Carboniferous. Dating of U-Pb age from basalt interbeds indicates that the redefined Gajinxueshan Group and Zhongxinrong Group may be considered Carboniferous to Permian and latest Permian to Middle Triassic in age. In geotectonic terms the Jinshajiang suture zone is thought to be a back-arc basin in the eastern margin of the Paleo-Tethys. This back-arc basin started in the Late Devonian, and formed in the Devonian-Carboniferous. The collision event around the Permian/Triassic boundary to the Middle Triassic led to the closure of the back-arc basin and formation of suture.展开更多
Dear Editor,Worldwide,around 55 million people had prevalent dementia in 2019,which is expected to triple by 2050,especially in low-and middle-income countries[1].Lacking timely diagnosis and limited effective treatme...Dear Editor,Worldwide,around 55 million people had prevalent dementia in 2019,which is expected to triple by 2050,especially in low-and middle-income countries[1].Lacking timely diagnosis and limited effective treatment for dementia make identifying risk factors crucial for its early prevention,among which dietary factors have received increasing attention[1].Recently,accumulating evidence from population-based studies has linked the temporal patterns of energy intake(TPEI),usually defined as the temporal distribution of energy intake during a day,to mortality and metabolic diseases[2],such as diabetes and hypertension.In vitro and in vivo studies also revealed that meal timing could drive metabolic alterations and circadian regulation[3],and disrupted meal timing altered the peripheral circadian clocks in the hippocampus and consequently affected cognitive function[4].展开更多
文摘Participation, support and understanding of countries along the Belt and Road are requisites for promoting and implementing this major initiative. Indonesia, a major ASEAN economy, is crucial but Indonesia has a limited perception of the B&R initiative. Although its government welcomes it and the ruling coalition cooperates positively, parts of the military and opposition are skeptical of China's intent. The B&R initiative is well-received among the Indonesian Chinese group, while Indonesian academic circles remain cautious and somewhat critical. From a Chinese viewpoint, easing negative or hostile emotions appropriately would be well-timed. China should settle the Natuna issue, adjust its publicity in Indonesia, use diplomacy, and promote Sino-Indonesia cultural exchange and communications. Chinese enterprises should focus on project quality and uphold social responsibilities. Short-term goals are reducing Indonesia's opposition and obstruction of B&R, while long-term goals are enhancing the recognition and likeability of the Initiative's worthwhile plans.
文摘Introduction Throughout a woman’s life,several unique health characteristics are related to an increased risk of later disease morbidity and/or premature mortality(Fig.1).For instance,these include early age at menarche1,2(ie,“short,irregular or long menstrual cycles”)3,4,a history of infertility5,pregnancy loss6,several major pregnancy complications(eg,preeclampsia,gestational hypertension,gestational diabetes mellitus(GDM)and preterm delivery)7–9,and menopause characteristics(eg,long menopause transition period,early age at menopause,and the presence of vasomotor symptoms).
文摘Over the past two decades,population-based studies employing semiautomatic computer-assisted programs have uncovered associations between retinal microvascular features and various systemic conditions.As the recognition of retinal imaging in cardiometabolic health grows,there is increasing evidence supporting its application in women’s health,particularly during the reproductive age.This review aims to summarize the indications of retinal imaging in women’s health and intergenerational health,where suboptimal retinal imaging has been found to mirror pathological systemic changes,such as suboptimal hemodynamic circulation,inflammation,endothelial dysfunction,oxidative stress,and hypoxia in vivo.Findings from Singapore Growing Up in Singapore Towards Healthy Outcomes and Singapore Preconception Study of Long-Term Maternal and Child Outcomes cohorts have reported serial changes in retinal conventional microvascular features(e.g.,retinal arteriolar narrowing,retinal venular widening)and retinal geometric microvascular features(e.g.,sparse fractal dimension,enlarged branching angle,and increased curvature tortuosity)during the preconception and antenatal phases.These morphological abnormalities were found to be related to female fertility,maternal antenatal health conditions,postnatal maternal cardiometabolic health,and intergenerational health in the fetus.Given the compelling evidence of the ability to detect microvascular changes through noninvasive methods at an early stage,retinal imaging holds the potential to facilitate timely interventions,mitigate the progression of complications,and prevent adverse pregnancy outcomes.Looking ahead,the convergence of artificial intelligence and advanced imaging techniques heralds a promising era in women’s health research and clinical practice.
文摘It is imperative that India and China regain past civilizational glory by showing sensitivity to each other's concerns and reaching goals through cooperation.
文摘The SCO summit aligns with India's worldview of"the world as a family,"as does the China-proposed Global Development Initiative,Global Security Initiative,and Global Civilization Initiative,all of which mark steps toward a shared future for mankind.The Shanghai Cooperation Organization(SCO)is an important and inclusive organization immune to Cold War baggage.Enjoying observer status at the United Nations General Assembly(UNGA),the SCO has full members,observers,and dialogue partners whose development,geopolitical,and national security interests converge.
文摘Integrated study of rock assemblage, tectonic setting, geochemical feature, fossil contained and isotopic geochronology on the metamorphic mixed bodies, exposed in the Jinshajiang suture zone, suggests that one informal lithostratigraphic unit, the Eaqing Complex, and three tectono-stratigraphic units, the Jinshajiang ophiolitic melange, the Gajinxueshan Group and the Zhongxinrong Group, can be recognized there. It is first pointed out that the redefined Eaqing Complex might represent the Meso- to Neo-Proterozoic remnant metamorphic basement or mi-crocontinental fragment in the Jinshajiang area. The original rocks of it should be older than (1627 ±192) Ma based on the geochronological study. The zircon U-Pb age of plagiogranites within the Jinshajiang ophiolitic assemblage is dated for the first time at (294 ± 3) Ma and (340 ± 3) Ma respectively. The Jinshajiang ophiolite is approximately equivalent to the Ailaoshan ophiolite in the formation age, covering the interval from the Late Devonian to the Carboniferous. Dating of U-Pb age from basalt interbeds indicates that the redefined Gajinxueshan Group and Zhongxinrong Group may be considered Carboniferous to Permian and latest Permian to Middle Triassic in age. In geotectonic terms the Jinshajiang suture zone is thought to be a back-arc basin in the eastern margin of the Paleo-Tethys. This back-arc basin started in the Late Devonian, and formed in the Devonian-Carboniferous. The collision event around the Permian/Triassic boundary to the Middle Triassic led to the closure of the back-arc basin and formation of suture.
基金We also acknowledge the support from the Key Laboratory of Intelligent Preventive Medicine of Zhejiang Province(2020E10004)This work was supported by the National Natural Science Foundation of China(92057109 to M.L.)the Zhejiang University Global Partnership Fund(C.Y.).
文摘Dear Editor,Worldwide,around 55 million people had prevalent dementia in 2019,which is expected to triple by 2050,especially in low-and middle-income countries[1].Lacking timely diagnosis and limited effective treatment for dementia make identifying risk factors crucial for its early prevention,among which dietary factors have received increasing attention[1].Recently,accumulating evidence from population-based studies has linked the temporal patterns of energy intake(TPEI),usually defined as the temporal distribution of energy intake during a day,to mortality and metabolic diseases[2],such as diabetes and hypertension.In vitro and in vivo studies also revealed that meal timing could drive metabolic alterations and circadian regulation[3],and disrupted meal timing altered the peripheral circadian clocks in the hippocampus and consequently affected cognitive function[4].
