Purpose: To investigate intraocular pressure (IOP) and ocular haemodynamics fo llowing small incision cataract surgery. Methods: Systemic and ocular haemodynam ics, and IOP, were measured pre-operatively and 1 month p...Purpose: To investigate intraocular pressure (IOP) and ocular haemodynamics fo llowing small incision cataract surgery. Methods: Systemic and ocular haemodynam ics, and IOP, were measured pre-operatively and 1 month post-operatively, in 2 5 eyes of 25 patients (mean age 72.6±7.9 years) scheduled for small incision ca taract surgery and intraocular lens implantation; these values were compared to an untreated age-matched healthy group (n=25, mean age 72.3±5.0 years). For ea ch eye, the Ocular Blood Flow Analyser (OBFA, Paradigm Inc., UT, USA) was used t o obtain measurements of IOP, pulsatile ocular blood flow (POBF), pulse volume ( PV), ocular pulse amplitude (PA), and pulse rate (PR). Systemic blood pressure m easurements were obtained at each visit. Pre-and post-operative values for the cataract group were compared using repeated measures analysis of variance, and compared to the normal group using analysis of variance. Results: Pre-operative ly, IOP was significantly higher in the cataract group compared to the age-matc hed normal control group (P < 0.001). Cataract surgery resulted in a significant 16.7%reduction in IOP (P=0.001). Consequently, the post-operative IOP in the cataract group was similar to that of the normal group (P > 0.05). Both pre-and post-operative POBF and PV values for the cataract groupwere significantly low er than for the normal age-matched group (P < 0.0125). Small incision cataract surgery led to an 8.3%post-operative increase in POBF (P=0.0118) and 15.5%inc rease in PV (P < 0.001). No changes in PA or PR were evident. Conclusion: These data suggest that cataract patients exhibit higher IOP and reduced ocular perfus ion characteristics compared to an age-matched normal healthy group. Following cataract surgery, IOP reduced and ocular pulsatility improved.展开更多
Aims: A pilot study of the safety and efficacy of deep sclerectomy with a chromic suture implant (DSCI) for open angle glaucoma. Methods: This prospective trial involved 23 eyes of 16 consecutive patients with uncontr...Aims: A pilot study of the safety and efficacy of deep sclerectomy with a chromic suture implant (DSCI) for open angle glaucoma. Methods: This prospective trial involved 23 eyes of 16 consecutive patients with uncontrolled open angle glaucoma. The DSCI procedure involved radial suturing of a 2mm piece of 1/0 chromic suture as an implant. Intraocular pressure (IOP) measurements and eye examinations were performed preoperatively and regularly postoperatively for up to 66 months. Results: The mean follow-up period was 36.3 (SD 19.9)-months. The mean preoperative IOPwas 26.3 (SD 8.5)mmHg. Themean postoperative IOPwas 14.1 (SD 2.8)mmHg atmonth 12, and 16.5 (SD 2.3)mmHg at 36 months. Complete success rate, defined as an IOPlower than 21mmHg without medication was 77%of eyes at 36 months. Qualified success rate, defined as an IOPl ower than 21mmHg with medication, was 100%at 36 months. Paired t-test andWilcoxon test analysis of preoperative vs postoperative IOPat 36 months indicated a significant reduction in IOP, Intraoperative complications included rupture of the trabecular meshwork in seven eyes. Exclusion of these patients from the results analysis revealed a mean follow-up of 37.1 months (SD 9), preoperative mean IOPwas 25.9mmHg (SD 4.1), 12-month mean IOPwas 13.4mmHg (SD 2.8), and 36-month mean IOP16.6mmHg (SD 2.1). Early postoperative complications included hyphaema in two eyes and dislocation of implant in one eye. One eye developed a central retinal vein occlusion and cataract progression occurred in one eye. The mean postoperative duration of use of topical dexamethasone was 5.4 months (SD 2). Conclusions: DSCI using a chromic suture implant provides good control of IOPat medium-term follow-upwith fewpostoperative complications. Prolonged use of postoperative anti-inflammatory medication was necessary.展开更多
文摘Purpose: To investigate intraocular pressure (IOP) and ocular haemodynamics fo llowing small incision cataract surgery. Methods: Systemic and ocular haemodynam ics, and IOP, were measured pre-operatively and 1 month post-operatively, in 2 5 eyes of 25 patients (mean age 72.6±7.9 years) scheduled for small incision ca taract surgery and intraocular lens implantation; these values were compared to an untreated age-matched healthy group (n=25, mean age 72.3±5.0 years). For ea ch eye, the Ocular Blood Flow Analyser (OBFA, Paradigm Inc., UT, USA) was used t o obtain measurements of IOP, pulsatile ocular blood flow (POBF), pulse volume ( PV), ocular pulse amplitude (PA), and pulse rate (PR). Systemic blood pressure m easurements were obtained at each visit. Pre-and post-operative values for the cataract group were compared using repeated measures analysis of variance, and compared to the normal group using analysis of variance. Results: Pre-operative ly, IOP was significantly higher in the cataract group compared to the age-matc hed normal control group (P < 0.001). Cataract surgery resulted in a significant 16.7%reduction in IOP (P=0.001). Consequently, the post-operative IOP in the cataract group was similar to that of the normal group (P > 0.05). Both pre-and post-operative POBF and PV values for the cataract groupwere significantly low er than for the normal age-matched group (P < 0.0125). Small incision cataract surgery led to an 8.3%post-operative increase in POBF (P=0.0118) and 15.5%inc rease in PV (P < 0.001). No changes in PA or PR were evident. Conclusion: These data suggest that cataract patients exhibit higher IOP and reduced ocular perfus ion characteristics compared to an age-matched normal healthy group. Following cataract surgery, IOP reduced and ocular pulsatility improved.
文摘Aims: A pilot study of the safety and efficacy of deep sclerectomy with a chromic suture implant (DSCI) for open angle glaucoma. Methods: This prospective trial involved 23 eyes of 16 consecutive patients with uncontrolled open angle glaucoma. The DSCI procedure involved radial suturing of a 2mm piece of 1/0 chromic suture as an implant. Intraocular pressure (IOP) measurements and eye examinations were performed preoperatively and regularly postoperatively for up to 66 months. Results: The mean follow-up period was 36.3 (SD 19.9)-months. The mean preoperative IOPwas 26.3 (SD 8.5)mmHg. Themean postoperative IOPwas 14.1 (SD 2.8)mmHg atmonth 12, and 16.5 (SD 2.3)mmHg at 36 months. Complete success rate, defined as an IOPlower than 21mmHg without medication was 77%of eyes at 36 months. Qualified success rate, defined as an IOPl ower than 21mmHg with medication, was 100%at 36 months. Paired t-test andWilcoxon test analysis of preoperative vs postoperative IOPat 36 months indicated a significant reduction in IOP, Intraoperative complications included rupture of the trabecular meshwork in seven eyes. Exclusion of these patients from the results analysis revealed a mean follow-up of 37.1 months (SD 9), preoperative mean IOPwas 25.9mmHg (SD 4.1), 12-month mean IOPwas 13.4mmHg (SD 2.8), and 36-month mean IOP16.6mmHg (SD 2.1). Early postoperative complications included hyphaema in two eyes and dislocation of implant in one eye. One eye developed a central retinal vein occlusion and cataract progression occurred in one eye. The mean postoperative duration of use of topical dexamethasone was 5.4 months (SD 2). Conclusions: DSCI using a chromic suture implant provides good control of IOPat medium-term follow-upwith fewpostoperative complications. Prolonged use of postoperative anti-inflammatory medication was necessary.
