<正>Autism is a complex neurobiological,developmental disorder that is typically diagnosed in childhood and often lasts throughout a person's life time. Autism is part of a group of disorders known as autis...<正>Autism is a complex neurobiological,developmental disorder that is typically diagnosed in childhood and often lasts throughout a person's life time. Autism is part of a group of disorders known as autism spectrum disorders (ASD) characterized by varying degrees of symptom severity and impact,ranging from mild or 'high-functioning' to quite severe or 'low-functioning.' The hallmark characteristics of autism include an impaired ability to communicate and relate to others socially. Autism is also associated with a restricted range of activities and repetitive behaviors,such as obsessively arranging objects or following very specific routines.ASD can usually be reliably diagnosed behaviorally by age 2,although new research is developing screening and diagnostic measures for children as young as 12-18 months of age. In 2007,the American Academy of Pedia-trics recommended screening of all children for ASD at 18 and 24 months of age. While there is no known cure,research indicates that early intervention in an appropriate educational setting for at least two years during the preschool years can result in significant improvements in language,cognitive ability,and social skills for many young children with autism spectrum disorders. Early detection and diagnosis is essential for maximizing the benefits of early intervention. As soon as autism is diagnosed,early intervention instruction should begin. Effective programs focus on developing communication,social,and cognitive skills[1].展开更多
This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multis...This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children.展开更多
文摘<正>Autism is a complex neurobiological,developmental disorder that is typically diagnosed in childhood and often lasts throughout a person's life time. Autism is part of a group of disorders known as autism spectrum disorders (ASD) characterized by varying degrees of symptom severity and impact,ranging from mild or 'high-functioning' to quite severe or 'low-functioning.' The hallmark characteristics of autism include an impaired ability to communicate and relate to others socially. Autism is also associated with a restricted range of activities and repetitive behaviors,such as obsessively arranging objects or following very specific routines.ASD can usually be reliably diagnosed behaviorally by age 2,although new research is developing screening and diagnostic measures for children as young as 12-18 months of age. In 2007,the American Academy of Pedia-trics recommended screening of all children for ASD at 18 and 24 months of age. While there is no known cure,research indicates that early intervention in an appropriate educational setting for at least two years during the preschool years can result in significant improvements in language,cognitive ability,and social skills for many young children with autism spectrum disorders. Early detection and diagnosis is essential for maximizing the benefits of early intervention. As soon as autism is diagnosed,early intervention instruction should begin. Effective programs focus on developing communication,social,and cognitive skills[1].
基金supported by the National Health Commission of the People’s Republic of China (201302002,Clinical Trial NCT02200679)。
文摘This study aimed to obtain the first national estimate of the prevalence of autism spectrum disorder(ASD) in Chinese children.We targeted the population of 6 to 12-year-old children for this prevalence study by multistage convenient cluster sampling.The Modified Chinese Autism Spectrum Rating Scale was used for the screening process.Of the target population of 142,086 children,88.5%(n=125,806) participated in the study.A total of 363 children were confirmed as having ASD.The observed ASD prevalence rate was 0.29%(95% CI:0.26%-0.32%) for the overall population.After adjustment for response rates,the estimated number of ASD cases was867 in the target population sample,thereby achieving an estimated prevalence of 0.70%(95% CI:0.64%-0.74%).The prevalence was significantly higher in boys than in girls(0.95%;95% CI:0.87%-1.02% versus 0.30%;95%CI:0.26%-0.34%;P <0.001).Of the 363 confirmed ASD cases,43.3% were newly diagnosed,and most of those(90.4%) were attending regular schools,and 68.8% of the children with ASD had at least one neuropsychiatric comorbidity.Our findings provide reliable data on the estimated ASD prevalence and comorbidities in Chinese children.
