Liver transplantation(LT)is fully established in conventional clinical care for patients with hepatocellular carcinoma(HCC).The long-term survival of transplanted patients competes with the survival offered by surgica...Liver transplantation(LT)is fully established in conventional clinical care for patients with hepatocellular carcinoma(HCC).The long-term survival of transplanted patients competes with the survival offered by surgical resection and this sets the scene for a debate for which a consensus answer based in evidence is not available.Resection outcomes have steadily improved due a refined selection of patients and the availability of other effective options such as ablation or locoregional approach(chemoembolization or radioembolization)has allowed to avoid its indication as a last effective resource for desperate cases.Same evolution has taken place for LT as it was early shown that if the tumor burden was reduced the survival results would be encouraging(1).展开更多
文摘Liver transplantation(LT)is fully established in conventional clinical care for patients with hepatocellular carcinoma(HCC).The long-term survival of transplanted patients competes with the survival offered by surgical resection and this sets the scene for a debate for which a consensus answer based in evidence is not available.Resection outcomes have steadily improved due a refined selection of patients and the availability of other effective options such as ablation or locoregional approach(chemoembolization or radioembolization)has allowed to avoid its indication as a last effective resource for desperate cases.Same evolution has taken place for LT as it was early shown that if the tumor burden was reduced the survival results would be encouraging(1).