基于自适应阻抗的构网型储能变流器控制策略研究

构网型储能变流器因具备调频调峰、削峰填谷及提高电力系统支撑等能力,已成为构建新型电力系统的重要设备之一。围绕构网型储能变流器接入电网时的稳定性展开研究。首先建立了构网型储能变流器接入电网时的数学模型,分析了在不同阻抗特性下对并网稳定性的影响。研究结果表明构网型储能变流器采用传统虚拟同步控制,当输出阻抗发生变化以及并离网切换时,容易引起系统振荡,不利于实现无缝切换。针对上述问题在传统虚拟同步控制的基础上加入了自适应阻抗控制,通过仿真验证,该控制策略可以实现不同电网工况下的阻抗适配以及并离网的无缝切换,有效提升了并网系统的稳定性。

Characteristics of PM_(2.5) pollution in Beijing after the improvement of air quality

Following the implementation of the strictest clean air policies to date in Beijing,the physicochemical characteristics and sources of PM_(2.5) have changed over the past few years.To improve pollution reduction policies and subsequent air quality further,it is necessary to explore the changes in PM_(2.5) over time.In this study,over one year(2017-2018)field study based on filter sampling(TH-150C;Wuhan Tianhong,China)was conducted in Fengtai District,Beijing,revealed that the annual average PM_(2.5) concentration(64.8±43.1μg/m^3)was significantly lower than in previous years and the highest PM_(2.5) concentration occurred in spring(84.4±59.9μg/m^3).Secondary nitrate was the largest source and accounted for 25.7%of the measured PM_(2.5).Vehicular emission,the second largest source(17.6%),deserves more attention when considering the increase in the number of motor vehicles and its contribution to gaseous pollutants.In addition,the contribution from coal combustion to PM_(2.5) decreased significantly.During weekends,the contribution from EC and NO3−increased whereas the contributions from SO4^2−,OM,and trace elements decreased,compared with weekdays.During the period of residential heating,PM_(2.5) mass decreased by 23.1%,compared with non-heating period,while the contributions from coal combustion and vehicular emission,and related species increased.With the aggravation of pollution,the contribution of vehicular emission and secondary sulfate increased and then decreased,while the contribution of NO3−and secondary nitrate continued to increase,and accounted for 34.0%and 57.5%of the PM_(2.5) during the heavily polluted days,respectively.

Rheological properties and concentration evolution of thickened tailings under the coupling effect of compression and shear

Cemented paste backfill(CPB)is a key technology for green mining in metal mines,in which tailings thickening comprises the primary link of CPB technology.However,difficult flocculation and substandard concentrations of thickened tailings often occur.The rheological properties and concentration evolution in the thickened tailings remain unclear.Moreover,traditional indoor thickening experiments have yet to quantitatively characterize their rheological properties.An experiment of flocculation condition optimization based on the Box-Behnken design(BBD)was performed in the study,and the two response values were investigated:concentration and the mean weighted chord length(MWCL)of flocs.Thus,optimal flocculation conditions were obtained.In addition,the rheological properties and concentration evolution of different flocculant dosages and ultrafine tailing contents under shear,compression,and compression-shear coupling experimental conditions were tested and compared.The results show that the shear yield stress under compression and compression-shear coupling increases with the growth of compressive yield stress,while the shear yield stress increases slightly under shear.The order of shear yield stress from low to high under different thickening conditions is shear,compression,and compression-shear coupling.Under compression and compression-shear coupling,the concentration first rapidly increases with the growth of compressive yield stress and then slowly increases,while concentration increases slightly under shear.The order of concentration from low to high under different thickening conditions is shear,compression,and compression-shear coupling.Finally,the evolution mechanism of the flocs and drainage channels during the thickening of the thickened tailings under different experimental conditions was revealed.

Association between Meeting 24-Hour Movement Guidelines and Psychological Features of Chinese Emerging Adults

Background:Emerging adulthood is a pivotal life stage,presenting significant psychological and social changes,such as decreased sociability,depression,and other mental health problems.Previous studies have associated these changes with an unhealthy lifestyle.The 24-h movement guidelines for healthy lifestyles have been developed to promote appropriate health behaviors and improve individual wellness.However,the relationship between adherence to the 24-h movement guidelines and different characteristics of Chinese emerging adults is yet to be explored.This cross-sectional study aimed to investigate the association between adherence to the 24-h movement guidelines and four characteristics(self-exploration,instability,possibilities,and responsibility)of Chinese emerging adults.Methods:Overall,1,510 Chinese emerging adults aged 18–29 years were included in this study.Each participant completed a self-administered questionnaire that included questions on adherence to the 24-h movement guidelines(physical activity,sedentary behavior,and sleep)and the inventory of dimensions of emerging adulthood.Multivariable logistic regression analysis was employed to investigate the associations between adherence to the 24-h movement guidelines and each of the four characteristics.Results:The proportion of participants who adhered to the 24-h movement guidelines was 31.72%.Multiple regression analysis revealed a significantly negative relationship between adhering to more guidelines and instability(β=−0.51,p<0.001).A statistically significant association was observed between instability and meeting only sedentary behavior(β=−1.27,95%confidence interval[CI]:[−2.32,−0.24],p=0.02),sedentary behavior+sleep(β=−1.30,95%CI:[−2.24,−0.35],p<0.01),and physical activity+sedentary behavior(β=−1.08,95%CI:[1.94,−0.21],p=0.02)guidelines.Further,positive and significant associations were observed between possibilities and meeting the guidelines for only physical activity(β=0.70,95%CI:[0.14,1.27),p=0.01),only sleep(β=0.61,95%CI:[0.01,1.21],p=0.04),physical activity+sedentary behavior(β=0.56,95%CI:[0.04,1.07),p=0.01),and physical activity+sleep(β=0.76,95%CI:[0.23,1.27],p=0.01).Conclusions:These findings suggest that adherence to the 24-h movement guidelines was associated with instability in Chinese emerging adults.Future studies are warranted to verify our findings to highlight the importance of maintaining a heath lifestyle to promote health in emerging adulthood.

招平断裂带大尹格庄矿区三维地质结构及断裂控矿规律

本文基于大尹格庄矿区264个钻孔资料,建立了矿区三维精细化地质模型,剖析了金矿床三维空间结构,指出了沿断裂构造深部找矿重点地段。三维可视化展现研究区浅部较为零散的矿体在深部连为一体,构成资源量超过200 t的超大型金矿床。对主要矿体开展品位、厚度及断裂构造形态变化的耦合关系表明,矿体存在沿走向、倾向等间距分布、侧伏和斜列分布规律,矿体富集区主要位于断裂沿倾向陡缓交替地段,进一步理清了断裂与金矿的耦合关系,显示了三维模型在深部找矿中的预测作用。

沙库巴曲缬沙坦钠联合左西孟旦治疗射血分数降低型心力衰竭有效性和安全性的Meta分析

目的:系统评价沙库巴曲缬沙坦钠联合左西孟旦治疗射血分数降低型心力衰竭(heart failure with reduced ejection fraction,HFrEF)的有效性与安全性。方法:计算机检索PubMed、The Cochrane Library、Embase、Web of science、中国生物医学文献服务系统、中国学术期刊全文数据库、维普中文科技期刊数据库和万方数据库。搜索沙库巴曲缬沙坦钠联合左西孟旦治疗HFrEF的相关随机对照试验,检索时限为建库至2023年12月。由两位研究者独自筛选文献、提取相关有效信息和纳入评价研究的偏移风险后,使用RevMan5.4.1分析工具进行Meta分析。结果:纳入12个研究,共计1234例患者。Meta分析结果显示:沙库巴曲缬沙坦钠联合左西孟旦组的NYHA心功能改善总有效率高于对照组(RR=4.46,95%CI:2.86~6.94,P<0.00001),LVEF高于对照组(MD=6.09,95%CI:5.57,6.60,P<0.00001),LVEDD低于对照组(MD=-3.90,95%CI:-4,75~3.06,P<0.00001),不良反应低于对照组(RR=0.39,95%CI:0.21~0.72,P=0.0.003)。结论:当前证据显示,沙库巴曲缬沙坦钠联合左西孟旦能改善NYHA心功能分级,提高射血分数及抑制心室重构,而未出现明显不良反应。

基于可信执行环境的安全推理研究进展

近年来,以深度神经网络为代表的机器学习技术在自动驾驶、智能家居和语音助手等领域获得了广泛应用。在上述高实时要求场景下,多数服务商将模型部署在边缘设备以规避通信带来的网络时延与通信开销。然而,边缘设备不受服务商控制,所部署模型易遭受模型窃取、错误注入和成员推理等攻击,进而导致高价值模型失窃、推理结果操纵及私密数据泄露等严重后果,使服务商市场竞争力受到致命打击。为解决上述问题,众多学者致力于研究基于可信执行环境(TEE)的安全推理,在保证模型可用性条件下保护模型的参数机密性与推理完整性。文章首先介绍相关背景知识,给出安全推理的定义,并归纳其安全模型;然后对现有TEE安全推理的模型机密性保护方案与推理完整性保护方案进行了分类介绍和比较分析;最后展望了TEE安全推理的未来研究方向。

Enhancing Geological Understanding and Identifying Gold Anomalies in the Ailaoshan Orogen

The Ailaoshan Orogen in the southeastern Tibet Plateau,situated between the Yangtze and Simao blocks,underwent a complex structural,magmatic,and metamorphic evolution resulting in different tectonic subzones with varying structural lineaments and elemental concentrations.These elements can conceal or reduce anomalies due to the mutual effect between different anomaly areas.Dividing the whole zone into subzones based on tectonic settings,ore cluster areas,or sample catchment basins(Scb),geochemical and structural anomalies associated with gold(Au)mineralization have been identified utilizing mean plus twice standard deviations(Mean+2STD),factor analysis(FA),concentration-area(CA)modeling of stream sediment geochemical data,and lineament density in both the Ailaoshan Orogen and the individual subzones.The FA in the divided 98 Scbs with 6 Scbs containing Au deposits can roughly ascertain unknown rock types,identify specific element associations of known rocks and discern the porphyry or skarn-type Au mineralization.Compared with methods of Mean+2STD and C-A model of data in the whole orogen,which mistake the anomalies as background or act the background as anomalies,the combined methods of FA and C-A in the separate subzones or Scbs works well in regional metallogenic potential analysis.Mapping of lineament densities with a 10-km circle diameter is not suitable to locate Au deposits because of the delineated large areas of medium-high lineament density.In contrast,the use of circle diameters of 1.3 km or 1.7 km in the ore cluster scale delineates areas with a higher concentration of lineament density,consistent with the locations of known Au deposits.By analyzing the map of faults and Au anomalies,two potential prospecting targets,Scbs 1 and 63 with a sandstone as a potential host rock for Au,have been identified in the Ailaoshan Orogen.The use of combined methods in the divided subzones proved to be more effective in improving geological understanding and identifying mineralization anomalies associated with Au,rather than analyzing the entire large area.

Core–Shell Microfiber Encapsulation Enables Glycerol‑Free Cryopreservation of RBCs with High Hematocrit

Cryopreservation of red blood cells(RBCs)provides great potential benefits for providing transfusion timely in emergencies.High concentrations of glycerol(20%or 40%)are used for RBC cryopreservation in current clinical practice,which results in cytotoxicity and osmotic injuries that must be carefully controlled.However,existing studies on the low-glycerol cryopreservation of RBCs still suffer from the bottleneck of low hematocrit levels,which require relatively large storage space and an extra concentration process before transfusion,making it inconvenient(time-consuming,and also may cause injury and sample lose)for clinical applications.To this end,we develop a novel method for the glycerol-free cryopreservation of human RBCs with a high final hematocrit by using trehalose as the sole cryoprotectant to dehydrate RBCs and using core–shell alginate hydrogel microfibers to enhance heat transfer during cryopreservation.Different from previous studies,we achieve the cryopreservation of human RBCs at high hematocrit(>40%)with high recovery(up to 95%).Additionally,the washed RBCs post-cryopreserved are proved to maintain their morphology,mechanics,and functional properties.This may provide a nontoxic,high-efficiency,and glycerol-free approach for RBC cryopreservation,along with potential clinical transfusion benefits.

Transfer force perception skills to robot‐assisted laminectomy via imitation learning from human demonstrations

A comparative study of two force perception skill learning approaches for robot‐assisted spinal surgery,the impedance model method and the imitation learning(IL)method,is presented.The impedance model method develops separate models for the surgeon and patient,incorporating spring‐damper and bone‐grinding models.Expert surgeons'feature parameters are collected and mapped using support vector regression and image navi-gation techniques.The imitation learning approach utilises long short‐term memory networks(LSTM)and addresses accurate data labelling challenges with custom models.Experimental results demonstrate skill recognition rates of 63.61%-74.62%for the impedance model approach,relying on manual feature extraction.Conversely,the imitation learning approach achieves a force perception recognition rate of 91.06%,outperforming the impedance model on curved bone surfaces.The findings demonstrate the potential of imitation learning to enhance skill acquisition in robot‐assisted spinal surgery by eliminating the laborious process of manual feature extraction.

Genomic characterization of peritoneal lavage cytology-positive gastric cancer

Objective: Positive peritoneal lavege cytology(CY1) gastric cancer is featured by dismal prognosis, with high risks of peritoneal metastasis. However, there is a lack of evidence on pathogenic mechanism and signature of CY1and there is a continuous debate on CY1 therapy. Therefore, exploring the mechanism of CY1 is crucial for treatment strategies and targets for CY1 gastric cancer.Methods: In order to figure out specific driver genes and marker genes of CY1 gastric cancer, and ultimately offer clues for potential marker and risk assessment of CY1, 17 cytology-positive gastric cancer patients and 31matched cytology-negative gastric cancer patients were enrolled in this study. The enrollment criteria were based on the results of diagnostic laparoscopy staging and cytology inspection of exfoliated cells. Whole exome sequencing was then performed on tumor samples to evaluate genomic characterization of cytology-positive gastric cancer.Results: Least absolute shrinkage and selection operator(LASSO) algorithm identified 43 cytology-positive marker genes, while Mut Sig CV identified 42 cytology-positive specific driver genes. CD3G and CDKL2 were both driver and marker genes of CY1. Regarding mutational signatures, driver gene mutation and tumor subclone architecture, no significant differences were observed between CY1 and negative peritoneal lavege cytology(CY0).Conclusions: There might not be distinct differences between CY1 and CY0, and CY1 might represent the progression of CY0 gastric cancer rather than constituting an independent subtype. This genomic analysis will thus provide key molecular insights into CY1, which may have a direct effect on treatment recommendations for CY1and CY0 patients, and provides opportunities for genome-guided clinical trials and drug development.

Experimental constraints on the formation of oxychlorine species by UV irradiation and mechanical pulverization on the lunar surface

Perchlorate and chlorate are present in various extraterrestrial celestial bodies throughout the solar system,such as Mars,the moon,and asteroids.To date,the origin mechanisms of perchlorate and chlorate on the Martian surface have been well-established;however,relatively little attention has been cast to airless bodies.Here,we experimentally investigated the potential oxidation mechanisms of chloride to chlorate and perchlorate,such as ultraviolet irradiation under H_(2)O-and O_(2)-free conditions and mechanical pulverization processes.Individual minerals,olivine,pyroxene,ilmenite,magnetite,TiO_(2)and anhydrous ferric sulfate,and lunar regolith simulants(low Ti,CLRS-1;high-Ti,CLRS-2)and their metallic iron(Fe^( 0))bearing counterparts were examined.We found that pulverization of dry matrix material-halite mixtures,even in the presence of O_(2),does not necessarily lead to perchlorate and chlorate formation without involving water.Under photocatalytic and H_(2)O and O_(2)-free conditions,olivine and pyroxene can produce oxychlorine(ClO_(x)^(−))species,although the yields were orders of magnitude lower than those under Martian-relevant conditions.Nanophase-Fe^(0)particles in the lunar regolith and the common photocatalyst TiO_(2)can facilitate the ClO_(x)^(−)formation,but their yields were lower than those with olivine.The oxides ilmenite and magnetite did not efficiently contribute to ClO_(x)^(−)production.Our results highlight the critical role of H_(2)O in the oxidation chloride to chlorate and perchlorate,and provide essential insights into the environmental influence on the formation of oxychlorine species on different celestial bodies.

A glycine-rich nuclear effector VdCE51 of Verticillium dahliae suppresses plant immune responses by inhibiting the accumulation of GhTRXH2

Verticillium dahliae is an important soil-borne fungal pathogen that causes great yield losses in many cash crops.Effectors of this fungus are known to regulate plant immunity but the mechanism much remains unclear.A glycine-rich nuclear effector,VdCE51,was able to suppress immune responses in tobacco against Botrytis cinerea and Sclerotinia sclerotiorum.This effector was a required factor for full virulence of V.dahliae,and its nuclear localization was a requisite for suppressing plant immunity.The thioredoxin GhTRXH2,identified as a positive regulator of plant immunity,was a host target of VdCE51.Our findings show a virulence regulating mechanism whereby the secreted nuclear effector VdCE51 interferes with the transcription of PR genes,and the SA signaling pathway by inhibiting the accumulation of GhTRXH2,thus suppressing plant immunity.

Independent prognostic value of lipocalin-2 in congenital heart disease-associated pulmonary artery hypertension

BACKGROUND Timely and accurate evaluation of the patient's pulmonary arterial pressure(PAP)is of great significance for the treatment of congenital heart disease.Currently,there is no non-invasive gold standard method for evaluating PAP.AIM To assess the prognostic value of lipocalin-2(LCN2)in relation to PAP in patients with congenital heart disease associated with pulmonary artery hypertension.METHODS We conducted a retrospective analysis of 69 pediatric patients diagnosed with ventricular septal defects.The patients’clinical and laboratory data were collected.The serum LCN2 concentrations were compared between the pulmonary arterial hypertension(PAH)group and the nonPAH group.The correlation of LCN2 concentration with PAH classification was evaluated using binary logistic regression analysis.The receiver operating characteristic(ROC)curve was used to evaluate the diagnostic potential of LCN2 for PAH.RESULTS Serum LCN2 concentration significantly correlated with patients’mean PAP(r=0.544,P<0.001),but not correlated with creatinine(P=0.446)or blood urea nitrogen(P=0.747).LCN2 levels were significantly correlated with PAH in both univariate[odds ratio(OR)1.107,95%CI:1.033-1.185,P=0.004)]and multivariate regression analysis(OR 1.150,95%CI:1.027-1.288,P=0.015).ROC curve analysis revealed an area under the curve of 0.783 for LCN2.At the cutoff value of 19.42 ng/mL,the sensitivity and specificity of LCN2 for diagnosing PAH is 90.19%and 55.56%,respectively.LCN2 concentration also significantly correlated with the post-repair mean PAP in patients with congenital heart disease(r=0.532,P=0.009).CONCLUSION LCN2 is emerging as a candidate biomarker for assessing PAP in patients with congenital heart disease.Its high sensitivity in diagnosing PAH makes it a valuable tool in patient management.

Machine learning assisted prediction for hydrogen production of advanced photovoltaic technologies

The photovoltaic(PV)water electrolysis method currently stands as the most promising approach for green hydrogen production.The rapid iteration of photovoltaic technologies has significantly affected on the technical and economic evaluation for photovoltaic hydrogen production.In this work,the photovoltaic hydrogen production of three most advanced silicon photovoltaic technologies is systematically compared for the first time under the climatic conditions of the Kucha region.All-weather stable hydrogen production control system with optimal charging and discharging strategies is constructed to realize stable and efficient hydrogen energy production.Seven machine learning(ML)algorithms are used to forecast the performance in power generation and hydrogen production of a 100 MW photovoltaic hydrogen production and energy storage(PH-S)system throughout its operational life.The long short-term memory(LSTM)algorithm exhibits the best performance,achieving mean absolute error(MAE)of 0.0415,root mean square error(RMSE)of 0.0891,and coefficient of determination(R2)of 0.8402.In terms of cost-effectiveness,heterojunction with intrinsic thin layer(HJT)PV technology achieves the lowest levelized cost of electricity(LCOE)and hydrogen(LCOH)at 0.025$/kWh and 6.95$/kg,respectively.According to the sensitivity analysis,when the cost of proton exchange membrane electrolysis(PEMEC)reduced 50%,the LCOH for PH-S system decreased 21.40%.This study provides valuable insights for the practical implementation of large-scale photovoltaic hydrogen production and cost reduction in PH-S systems.

四川盆地磨溪地区灯四段风化壳岩溶储层特征

近年来,四川盆地磨溪地区灯四段的油气勘探取得了重大突破,为研究磨溪22井区灯四上亚段优质岩溶储层特征及分布规律,开展了岩心分析、物性测试、地震资料解释、测井分析和有利岩溶储层发育区预测等工作。结果表明:①岩溶储层的岩性主要为藻云岩类、砂屑云岩类和结晶云岩类,储集空间主要为溶蚀孔、溶洞和裂缝;②溶蚀作用包括同生期大气淡水的溶蚀作用、埋藏期深部热液溶蚀作用和有机酸的溶蚀作用、表生期大气淡水的溶蚀作用;③表生期的溶蚀作用控制了优质储层的分布,多发育于垂直渗流带附近和水平潜流带上部区域,平面上优质储层的分布受控于沉积相带和古地貌特征,以丘滩相和溶丘斜坡较好。该研究成果为磨溪地区下一步勘探指明了方向。

不同硫含量石油焦中低温煅烧性能及脱硫机理研究

在实验室煅烧炉内对三种不同品种石油焦进行了700~1100℃阶段热处理,并对煅烧后的石油焦真密度、粉末电阻率、Lc值、气孔率等进行了检测分析,同时将煅烧后的石油焦颗粒进行了扫描电镜分析。通过分析研究发现,随着煅烧温度的增加,低硫、中硫、高硫石油焦TG和DTG曲线、煅烧后的性能、脱硫率、碳晶格的生长、气孔率等区别明显,这可为生产使用这三种类型硫含量的石油焦提供试验依据。

Caprini评估模型筛选老年重症肺炎深静脉血栓的有效性

目的分析老年重症肺炎合并深静脉血栓(deep venous thrombosis,DVT)的临床特点,回顾性验证Caprini风险评估模型筛选老年重症肺炎静脉血栓栓塞症的有效性。方法采用病例对照研究设计,收集2015年度本院内科年龄≥65岁,重症肺炎合并DVT患者50例为病例组,采用随机数字表法与病例组2:1比例随机选取同时期的老年重症肺炎无DVT患者100例为对照组。回顾性收集患者临床表现、实验室检查、治疗等相关资料,采用Caprini评估量表对两组患者进行评分及VTE危险度分级。比较两组临床表现、凝血功能、炎性指标,采用多因素logistic回归分析重症肺炎患者DVT风险因素,及VTE危险度分级与重症肺炎患者VTE发病风险的关系。结果两组临床表现中,DVT组卧床、下肢水肿及中心静脉置管的人数明显高于对照组(P<0.05),凝血指标显示DVT组D二聚体值(1718±140)mg/L显著高于对照组(923±76)mg/L(P<0.05),炎性指标显示DVT组的C反应蛋白值(87.75±6.78)mg/L显著高于对照组(56.29±4.43)mg/L(P<0.05),对照组血红蛋白值(117±26)g/L显著高于DVT组(105±22)g/L(P<0.05),且对照组的抗凝治疗率明显高于DVT组(P<0.05)。回归分析显示下肢水肿、中心静脉置管、D二聚体值与血栓发生显著相关(P<0.05)。DVT组Caprini评分均值(8.92±2.72)显著高于对照组(7.16±2.15)(P<0.05)。极高危组和高危组对比,随着评分等级的增加患者发生VTE的风险明显增加,评分≥9分的极高危患者发生VTE的风险是高危组的3.313倍(P<0.05)。结论老年重症肺炎患者下肢水肿、中心静脉置管及D二聚体值与血栓发生显著相关。Caprini风险分级能够有效的预测重症肺炎患者血栓发生的风险,值得临床推广。

涡轮转子凹槽叶尖泄漏流动气动热力特征

为探索总结凹槽叶尖泄漏流动气动热力特征,利用实验和数值模拟方法,对叶尖凹槽内部旋涡相互作用机理和叶顶流动换热与泄漏流能量再分布等问题进行研究,并对凹槽叶尖参数化设计方法进行探讨。结果表明:搭建的考虑多因素实验台和可视化泄漏流动测量方案可以精确地捕捉到叶顶区域的流动结构;刮削涡在凹槽中起到"气动篦齿"作用,其形态特征的变化直接影响凹槽叶尖对泄漏流动的控制效果;高温泄漏流流体对叶片表面的冲击是叶尖热负荷提高的主要原因;合理选择叶尖气动参数和凹槽的几何参数可以有效控制刮削涡形态,最终提升叶尖气动热力性能。

聚醚醚酮棒与钛棒在后路腰椎椎间融合中的有限元分析

背景:聚醚醚酮棒是一种新型的半刚性固定材料,但是其在后路腰椎椎间融合术中的生物力学性能仍不清楚。目的:对比聚醚醚酮棒与钛棒在后路腰椎椎间融合过程中的生物力学性能,尝试回答聚醚醚酮棒是否有潜力成为钛棒的替代品,尤其在前柱支撑不充分的情况下。方法:利用有限元方法构建完整的人腰椎(L)模型,并进一步构建4个后路腰椎椎间融合模型:①聚醚醚酮棒+cage;②钛棒+cage;③聚醚醚酮棒+纯植骨;④钛棒+纯植骨。比较不同模型中节段活动度、相关结构应力以及应变。结果与结论:①所有手术模型在限制L节段活动度方面无明显差异;②与钛棒相比,聚醚醚酮棒增加了椎间植骨的平均应变、增加了终板以及cage的峰值应力,同时降低了螺钉以及骨-螺钉界面的峰值应力;聚醚醚酮棒的峰值应力与屈服应力之比为6%-26%,高于钛棒的3%-12%;③在L节段上,聚醚醚酮棒仅轻微地降低了节段活动度与椎间盘峰值应力;④因此与钛棒相比,聚醚醚酮棒可能降低假关节、螺钉断裂与松动的风险,但是也可能导致终板塌陷、cage损坏以及棒断裂的风险更高;聚醚醚酮棒在延缓邻近节段退变中可能较钛棒有微弱的优势;在不使用cage而仅采用骨移植物进行椎间融合时,聚醚醚酮棒也许是一个可供选择的方案。