The Interdisciplinary Research of Big Data and Wireless Channel: A Cluster-Nuclei Based Channel Model

Recently,internet stimulates the explosive progress of knowledge discovery in big volume data resource,to dig the valuable and hidden rules by computing.Simultaneously,the wireless channel measurement data reveals big volume feature,considering the massive antennas,huge bandwidth and versatile application scenarios.This article firstly presents a comprehensive survey of channel measurement and modeling research for mobile communication,especially for 5th Generation(5G) and beyond.Considering the big data research progress,then a cluster-nuclei based model is proposed,which takes advantages of both the stochastical model and deterministic model.The novel model has low complexity with the limited number of cluster-nuclei while the cluster-nuclei has the physical mapping to real propagation objects.Combining the channel properties variation principles with antenna size,frequency,mobility and scenario dug from the channel data,the proposed model can be expanded in versatile application to support future mobile research.

Radiofrequency sensing systems based on emerging two-dimensional materials and devices

As one of the most promising platforms for wireless communication,radiofrequency(RF)electronics have been widely advocated for the development of sensing systems.In particular,monolayer and few-layer two-dimensional(2D)materials exhibiting extraordinary electrical properties not only can be integrated to improve the performance of RF circuits,but also to display exceptional sensing capabilities.This review provides an in-depth perspective of current trends and challenges in the application of 2D materials for RF biochemical sensing,including:(i)theoretical bases to achieve different sensing schemes;(ii)unique properties of 2D materials for reasoning their applications in RF sensing;(iii)developments in 2D RF sensors to facilitate the practice of biochemical sensors with ever-demanding sensitivities,as well as their potential uses in meeting the requirements and challenges of biochemical sensors in the Internet-of-Things era.

Effects of Intravenous Thrombolytic Therapy with Alteplase on Neurological Function,Coagulation Function and Serum Inflammatory Factors in Patients with Acute Cerebral Infarction

Objective:To investigate the effects of intravenous thrombolysis therapy with alteplase on neurological function,coagulation function and serum inflammatory factors in patients with acute cerebral infarction.Methods:A total of 96 patients with acute cerebral infarction admitted to our hospital from September 2017 to October 2019 were randomly divided into two groups,with 48 patients in each group.The control group(n=48)received routine treatment,and the observation group received intravenous thrombolysis therapy with alteplase on the basis of routine treatment.The neurological deficit score,prothrombin time(PT),activated partial thromboplastin time(APTT),tumor necrosis factor-a level(TNF-α),and high-sensitivity C-reactive protein(hs-CRP)were compared between the two groups after 15 days of treatment.Results:After treatment,NIHSS scores in both groups were lower than those before treatment;PT levels were increased,while APTT,TNF-αand hs-CRP levels were all decreased in both groups,and the changes in the observation group were greater than those in the control group,with statistically significant difference(P<0.05).Conclusions:Intravenous thrombolysis therapy with alteplase can improve the neurological function,coagulation function and serum levels of inflammatory factors in patients with acute cerebral infarction,which is worthy of clinical application.

Clinical Analysis of Cataract Surgery Complicated by Endophthalmitis

Purpose:.To assess the efficacy of vitrectomy combined with intravitreal injection in the treatment of endophthalmitis after phacoemulsification and IOL implantation. Methods:.Five patients.(5 eyes),.who had undergone conventional phacoemulsification combined with IOL implantation at another treatment facility,.presented with endophthalmitis. The subjects ranged in age from 41 to 79 years (65.8±0.5 years on average),.and three were male..All five cases received bacterial culture susceptibility testing..On the basis of the treatment of primary disease, 3 cases had anterior chamber irrigation,.and posterior vitrectomy followed by intravitreal injection of 1 mg vancomycin plus 2.25 mg ceftazidime. Results:.Four out of the five cases of endophthalmitis had a positive bacterial culture testing results.(two cases of staphylococcus epidermidis,.one case of enterococcus faecalis and one case of head-like staphylococcus),.and the remaining case had no bacterial growth..Four cases showed restored visual acuity,.clear vitreous cavity,.and no retinal detachment or other complications. Conclusion: Management of patients presenting with endophthalmitis subsequent to cataract surgery should include: prompt bacterial culture and drug sensitivity tests, and where appropriate, vitrectomy combined with intravitreal injection of vancomycin.

Clinical Study of Xingnaojing Injection Combined with Craniocerebral Hypothermia Apparatus in the Treatment of Acute Hemorrhagic Stroke

Objective:To investigate the clinical effect of Xingnaojing injection combined with craniocerebral hypothermia apparatus in the treatment of acute hemorrhagic stroke.Methods:Seventy-two patients with acute hemorrhagic stroke admitted to our hospital from March 2018 to September 2019 were randomly divided into two groups,with 36 cases in each group.The control group(n=36)was treated with craniocerebral hypothermia apparatus,and the observation group(n=36)was treated with Xingnaojing injection combined with craniocerebral hypothermia apparatus.The clinical efficacy,the National Institutes of Health Stroke Scale(NIHSS)score and the activity of daily living(MBI score)after 1 month of treatment were compared.Results:The effective rate of treatment in the observation group was higher than that in the control group(P<0.05);NIHSS score was decreased in both groups(P<0.05);MBI score was increased in both groups,and the change range of the observation group was greater than that of the control group,showing statistically significant differences(P<0.05).Conclusion:Xingnaojing injection combined with craniocerebral hypothermia apparatus can improve the clinical efficacy,the neurological impairment and activity of daily living in the treatment of acute hemorrhagic stroke,which is worthy of clinical application.

Effect of swimming training on the nerve injury, nerve cytokine expression and related signaling pathway in rats with cerebral infarction

Objective:To study the effect of swimming training on the nerve injury, nerve cytokine expression and related signaling pathway in rats with cerebral infarction.Methods: SD male rats were selected as the experimental animals and randomly divided into control group, cerebral infarction group and intervention group, control group received sham operation, cerebral infarction group were made into cerebral infarction models through suture method, and intervention group were made into cerebral infarction models through suture method and received swimming training. 21 d after intervention, serum was collected to determine the contents of nerve injury indexes and nerve cytokines, and brain tissue was collected to determine the expression levels of nerve apoptosis molecules, nerve cytokines and signaling pathway molecules.Results: Brain tissue CytC, Bax, Caspase-3, TLR4, NF-kB, MyD88, JAK2 and STAT3 contents as well as serum NSE and S100B contents of cerebral infarction group were significantly higher than those of control group while NGF, BDNF and NT-3 contents in the brain tissue and serum were significantly lower than those of control group;brain tissue CytC, Bax, Caspase-3, TLR4, NF-kB, MyD88, JAK2 and STAT3 contents as well as serum NSE and S100B contents of intervention group were significantly lower than those of cerebral infarction group while NGF, BDNF and NT-3 contents in the brain tissue and serum were significantly higher than those of cerebral infarction group.Conclusion:Swimming training can improve the neural function of rats with cerebral infarction, and inhibiting neuron apoptosis and improving neuron nutrition are the molecular mechanisms for swimming training to promote the neural functional recovery.

Critical audit matters and stock price crash risk

Using manually collected data on the number and category of critical audit matters(CAMs)in the period 2016–2017,we investigate the hitherto unexplored questions of whether CAMs affect firm-specific crash risk,how CAMs influence crash risk in the Chinese capital market,and recognize CAMs that contain incremental information.Our findings are as follows:(1)Crash risk decreases after implementing the new audit standard requiring the disclosure of CAMs;(2)CAMs release negative information and change the capital market information environment;(3)only corporateidiosyncratic CAMs contain incremental information;(4)crash risk is mitigated only by CAMs disclosed by companies with a high shareholding of institutional investors.The main conclusion of our study is a positive assessment of the new audit standard and of CAMs in terms of protecting the interests of investors and strengthening the stability of the capital market to provide a new perspective for supervising the implementation of the new audit standard.

The Chinese Society of Clinical Oncology(CSCO)clinical guidelines for the diagnosis and treatment of nasopharyngeal carcinoma

Nasopharyngeal carcinoma(NPC)is a malignant epithelial tumor originating in the nasopharynx and has a high incidence in Southeast Asia and North Africa.To develop these comprehensive guidelines for the diagnosis and management of NPC,the Chinese Society of Clinical Oncology(CSCO)arranged a multi-disciplinary team comprising of experts from all sub-specialties of NPC to write,discuss,and revise the guidelines.Based on the findings of evidencebased medicine in China and abroad,domestic experts have iteratively developed these guidelines to provide proper management of NPC.Overall,the guidelines describe the screening,clinical and pathological diagnosis,staging and risk assessment,therapies,and follow-up of NPC,which aim to improve the management of NPC.

An Asymmetric Natural Nanofiber with Rapid Temperature Responsive Detachability Inspired by Andrias davidianus for Full‑Thickness Skin Wound Healing

Wound dressing management is critical in healthcare,and frequent dressing changes for full-thickness skin wounds can hinder healing.Nanofiber dressings that resemble the extracellular matrix,have gained popularity in wound repair,however,it is challenging to explore how to frequently change it without affecting healing processing and avoiding secondary damage.Here,we developed a self-adhesive and detachable nanofiber dressing inspired by Andrias davidianus.Our asymmetric nanofiber dressing exhibits strong adhesion(26 kPa),to the wound at high temperature(approximately 25°C)to the wound surface and can be easily detached(4 kPa)at low temperature(below 8°C),enabling painless dressing changes that minimize secondary injuries.The dressing comprises an outer layer of polylactic acid which provides mechanical property,support,and pollution resistance,with an inner layer of nanofibrous membrane,composed of gelatin and Andrias davidianus skin secretions,which promotes cellular migration,enhances wound healing and possesses inherent antimicrobial properties.Furthermore,the all-natural nanofiber dressings can be prepared on a large scale and offer favorable biocompatibility to meet the basic requirements of wound dressings.These findings demonstrate the potential applicability of our multilayer nanofiber dressing for advancing wound healing practices.