Hand,foot,and mouth disease (HFMD) is an acute infection caused by enteroviruses that is commonly seen in children^([1]).High infectivity,large number of asymptomatic infections,complex transmission routes,and rapid s...Hand,foot,and mouth disease (HFMD) is an acute infection caused by enteroviruses that is commonly seen in children^([1]).High infectivity,large number of asymptomatic infections,complex transmission routes,and rapid spread make it difficult to control HFMD.Since 2008,China has reported> 23 million HFMD cases,including>0.15million severe cases^([2]).HFMD tops the list of notifiable infectious diseases in terms of case number and incidence rate,leading to a huge disease burden^([3]).Timely and accurate assessment of HFMD epidemics is essential for a holistic understanding of the outbreaks and for effective prevention and control strategies.Currently,there are no quantitative indicators to determine the duration and intensity of HFMD epidemics in Beijing.展开更多
Summary What is already known about this topic?Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)continues to evolve,the clinical manifestations resulting from different SARS-CoV-2 variants may demonstrate si...Summary What is already known about this topic?Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)continues to evolve,the clinical manifestations resulting from different SARS-CoV-2 variants may demonstrate significant variation.What is added by this report?We conducted a comparative analysis of the clinical features associated with SARS-CoV-2 Omicron subvariants BF.7.14 and BA.5.2.48 infections.The results of our study indicate that there are no substantial differences in clinical manifestations,duration of illness,healthcare-seeking behaviors,or treatment between these two subvariants.What are the implications for public health practice?Timely identification of alterations in the clinical spectrum is crucial for researchers and healthcare practitioners in order to enhance their comprehension of clinical manifestations,as well as the progression of SARS-CoV-2.Furthermore,this information is beneficial for policymakers in the process of revising and implementing appropriate countermeasures.展开更多
基金supported by National Key R&D Program of China [2021ZD0114103]Capital’s Funds for Health Improvement and Research [2022-1G-3014]+3 种基金High Level Public Health Technical Talent Training Plan [xuekegugan-01-019]High Level Public Health Technical Talent Training Plan [xuekedaitouren-01-03]Beijing Natural Science Foundation[7202073]Key research projects of Beijing Natural Science Foundation-Haidian District Joint Fund [L192012]。
文摘Hand,foot,and mouth disease (HFMD) is an acute infection caused by enteroviruses that is commonly seen in children^([1]).High infectivity,large number of asymptomatic infections,complex transmission routes,and rapid spread make it difficult to control HFMD.Since 2008,China has reported> 23 million HFMD cases,including>0.15million severe cases^([2]).HFMD tops the list of notifiable infectious diseases in terms of case number and incidence rate,leading to a huge disease burden^([3]).Timely and accurate assessment of HFMD epidemics is essential for a holistic understanding of the outbreaks and for effective prevention and control strategies.Currently,there are no quantitative indicators to determine the duration and intensity of HFMD epidemics in Beijing.
基金Supported by the National Key Research and Development Program of China(2021ZD0114103).
文摘Summary What is already known about this topic?Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)continues to evolve,the clinical manifestations resulting from different SARS-CoV-2 variants may demonstrate significant variation.What is added by this report?We conducted a comparative analysis of the clinical features associated with SARS-CoV-2 Omicron subvariants BF.7.14 and BA.5.2.48 infections.The results of our study indicate that there are no substantial differences in clinical manifestations,duration of illness,healthcare-seeking behaviors,or treatment between these two subvariants.What are the implications for public health practice?Timely identification of alterations in the clinical spectrum is crucial for researchers and healthcare practitioners in order to enhance their comprehension of clinical manifestations,as well as the progression of SARS-CoV-2.Furthermore,this information is beneficial for policymakers in the process of revising and implementing appropriate countermeasures.
