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Apoptosis induced by norcantharidin in human tumor cells 被引量:31
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作者 Zhen Xiao Sun Qing Wen Ma +3 位作者 Tian De Zhao Yu Lin Wei Guang Sheng Wang Jia Shi Li 《World Journal of Gastroenterology》 SCIE CAS CSCD 2000年第2期263-265,共3页
INTRODUCTIONThe antitumor activity of norcantharidin (NCTD),the demethylated analogue of cantharidin,wasstudied in the early 1980s in China.NCTD has noside effects on urinary organs which cantharidin hasshown and is e... INTRODUCTIONThe antitumor activity of norcantharidin (NCTD),the demethylated analogue of cantharidin,wasstudied in the early 1980s in China.NCTD has noside effects on urinary organs which cantharidin hasshown and is easier to synthesize,and it can inhibitthe proliferation of several tumor cell lines as wellas transplanted tumors.Clinical trials with NCTD asa monotherapeutic agent indicated that NCTD hadbeneficial effects in patients with different kinds 展开更多
关键词 NORCANTHARIDIN ONCOPROTEIN Bcl-2 APOPTOSIS liver NEOPLASMS IMMUNOHISTOCHEMISTRY Western BLOT analysis
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