An immunomagnetic bead kit to separate and enrich salbutamol was prepared through the reaction between salbutamol and 4-aminobenzoic acid.The kit had a catch of 20 ng/ml to salbutamol in samples,and showed no cross re...An immunomagnetic bead kit to separate and enrich salbutamol was prepared through the reaction between salbutamol and 4-aminobenzoic acid.The kit had a catch of 20 ng/ml to salbutamol in samples,and showed no cross reaction with competitive drugs with structure and function similar to salbutamol: clenbuterol,ractopamine,phenylethanolamine A, bromchlorbuterol, brombuterol, terbutaline, hydroxymethyl salbutamol,cimaterol,tulobuterol,mapenterol,cimbuterol,clenpenterol,zilpaterol,penbutolol,clenproperol,mabuterol and clorprenaline.展开更多
[Objectives] This study was conducted to establish a method for rapid detection of Salmonella at the grassroots level, and a corresponding product was developed. [Methods] By analyzing the invA gene of Salmonella, two...[Objectives] This study was conducted to establish a method for rapid detection of Salmonella at the grassroots level, and a corresponding product was developed. [Methods] By analyzing the invA gene of Salmonella, two pairs of efficient, rapid and specific amplification primers were designed and screened for the six conserved domains of the gene, and the LAMP detection kit for Salmonella based on this method was produced. [Results] The method is simple, sensitive, rapid and specific. The minimum detection concentration is 10~2-10~3 CFU/ml. [Conclusions] It can be used in the self-inspection of food production enterprises and the on-site sampling inspection and rapid detection of large quantities of samples by grassroots food safety inspection and supervision departments.展开更多
Dear Editor,The ongoing threat of tick-borne diseases,especially the increasing rate of new infections caused by tick-borne viruses has drawn wide attention in recent years(Madison-Antenucci et al.,2020;Yang et al.,20...Dear Editor,The ongoing threat of tick-borne diseases,especially the increasing rate of new infections caused by tick-borne viruses has drawn wide attention in recent years(Madison-Antenucci et al.,2020;Yang et al.,2023).Therefore,there is a need to strengthen the surveillance of a wide range of viruses carried by ticks to prevent outbreaks of tick-borne diseases.展开更多
Plastic products widespread in natural water can be broken into smaller-sized microplastics(MPs,<5 mm)under light irradiation,thermal degradation and biodegradation,posing a serious threat to aquatic ecosystems and...Plastic products widespread in natural water can be broken into smaller-sized microplastics(MPs,<5 mm)under light irradiation,thermal degradation and biodegradation,posing a serious threat to aquatic ecosystems and human health.This perspective concludes that MPs can generate reactive oxygen species(ROS)through initiation,propagation and termination steps,which can attack the polymer resulting in the photoaging and breakdown of C–C and C–H bonds under ultraviolet(UV)irradiation.Free radical generation and weathering degree of MPs depend on their physicochemical properties and environmental conditions.In general,UV irradiation and co-existed MPs can significantly accelerate MP photoaging.With plentiful chromophores carbonyl,carboxyl and benzene rings,Dissolved organic matter(DOM)mainly absorbs photons(300–500 nm)and generates hydrated electrons,^(3)DOM^(*) and ROS,which may affect MP photoaging.However,whether DOM may transfer the electron and energy to MPs under UV irradiation,affect ROS generation of MPs and their photoaging pathway are inadequately studied.More studies are needed to elucidate MP photoaging pathways and mechanisms,consider the influence of stabilization capacity,photosensitization and photoionization of DOM as well as their competitive light absorption with MPs,which provides valuable insights into the environmental behavior and ecological risk of MPs in natural water.展开更多
A series of thermoplastic polyimide resins with a low coefficient of thermal expansion(CTE)were prepared by blending a rigid resin system 3,3’,4,4’-biphenyltetracarboxylic dianhydride(BPDA)/p-phenylenediamine(PDA)wi...A series of thermoplastic polyimide resins with a low coefficient of thermal expansion(CTE)were prepared by blending a rigid resin system 3,3’,4,4’-biphenyltetracarboxylic dianhydride(BPDA)/p-phenylenediamine(PDA)with a flexible resin system 4,4’-[isopropylidenebis(pphenyleneoxy)]diphthalic anhydride(BPADA)/PDA.The effects of the blending ratio on the macromolecular coil size,free volume,and CTE of the mixed system were studied.The mixing is carried out in the prepolymer poly(amide acid)(PAA)stage,which makes the two systems more compatible and is conducive to the formation of a semi-interpenetrating network structure between the rigid molecular chains and flexible molecular chains.The flexible structure of the BPADA/PDA system is used to ensure the melt processing performance.The rigid characteristics of the BPDA/PDA system can inhibit the movement of molecular chains and reduce the free volume fraction,thereby reducing the CTE value.When the rigid system content reaches 30%,the CTE can be reduced to 38 ppm/K.This method provides a new approach for studying low CTE thermoplastic polyimide resins.展开更多
基金Supported by Beijing Training Project for the Leading Talents in S&T(Z171100001117158)
文摘An immunomagnetic bead kit to separate and enrich salbutamol was prepared through the reaction between salbutamol and 4-aminobenzoic acid.The kit had a catch of 20 ng/ml to salbutamol in samples,and showed no cross reaction with competitive drugs with structure and function similar to salbutamol: clenbuterol,ractopamine,phenylethanolamine A, bromchlorbuterol, brombuterol, terbutaline, hydroxymethyl salbutamol,cimaterol,tulobuterol,mapenterol,cimbuterol,clenpenterol,zilpaterol,penbutolol,clenproperol,mabuterol and clorprenaline.
基金Supported by Guangxi Key R&D Program(GK AB16380271)
文摘[Objectives] This study was conducted to establish a method for rapid detection of Salmonella at the grassroots level, and a corresponding product was developed. [Methods] By analyzing the invA gene of Salmonella, two pairs of efficient, rapid and specific amplification primers were designed and screened for the six conserved domains of the gene, and the LAMP detection kit for Salmonella based on this method was produced. [Results] The method is simple, sensitive, rapid and specific. The minimum detection concentration is 10~2-10~3 CFU/ml. [Conclusions] It can be used in the self-inspection of food production enterprises and the on-site sampling inspection and rapid detection of large quantities of samples by grassroots food safety inspection and supervision departments.
文摘Dear Editor,The ongoing threat of tick-borne diseases,especially the increasing rate of new infections caused by tick-borne viruses has drawn wide attention in recent years(Madison-Antenucci et al.,2020;Yang et al.,2023).Therefore,there is a need to strengthen the surveillance of a wide range of viruses carried by ticks to prevent outbreaks of tick-borne diseases.
基金supported by the Fund for National Key R&D Program of China(No.2021YFC3200401)the National Natural Science Foundation of China(Nos.52170024,21677015,22006031).
文摘Plastic products widespread in natural water can be broken into smaller-sized microplastics(MPs,<5 mm)under light irradiation,thermal degradation and biodegradation,posing a serious threat to aquatic ecosystems and human health.This perspective concludes that MPs can generate reactive oxygen species(ROS)through initiation,propagation and termination steps,which can attack the polymer resulting in the photoaging and breakdown of C–C and C–H bonds under ultraviolet(UV)irradiation.Free radical generation and weathering degree of MPs depend on their physicochemical properties and environmental conditions.In general,UV irradiation and co-existed MPs can significantly accelerate MP photoaging.With plentiful chromophores carbonyl,carboxyl and benzene rings,Dissolved organic matter(DOM)mainly absorbs photons(300–500 nm)and generates hydrated electrons,^(3)DOM^(*) and ROS,which may affect MP photoaging.However,whether DOM may transfer the electron and energy to MPs under UV irradiation,affect ROS generation of MPs and their photoaging pathway are inadequately studied.More studies are needed to elucidate MP photoaging pathways and mechanisms,consider the influence of stabilization capacity,photosensitization and photoionization of DOM as well as their competitive light absorption with MPs,which provides valuable insights into the environmental behavior and ecological risk of MPs in natural water.
基金financially supported by the National Natural Science Foundation of China(No.51773007)the Fundamental Research Funds for the Central Universities(No.XK1802-2)。
文摘A series of thermoplastic polyimide resins with a low coefficient of thermal expansion(CTE)were prepared by blending a rigid resin system 3,3’,4,4’-biphenyltetracarboxylic dianhydride(BPDA)/p-phenylenediamine(PDA)with a flexible resin system 4,4’-[isopropylidenebis(pphenyleneoxy)]diphthalic anhydride(BPADA)/PDA.The effects of the blending ratio on the macromolecular coil size,free volume,and CTE of the mixed system were studied.The mixing is carried out in the prepolymer poly(amide acid)(PAA)stage,which makes the two systems more compatible and is conducive to the formation of a semi-interpenetrating network structure between the rigid molecular chains and flexible molecular chains.The flexible structure of the BPADA/PDA system is used to ensure the melt processing performance.The rigid characteristics of the BPDA/PDA system can inhibit the movement of molecular chains and reduce the free volume fraction,thereby reducing the CTE value.When the rigid system content reaches 30%,the CTE can be reduced to 38 ppm/K.This method provides a new approach for studying low CTE thermoplastic polyimide resins.