This article was carried out to gather a collection of data extracted from several studies about the snake Lachesis muta muta(surucucu),encompassing in this information from the effects and properties of its venom,cas...This article was carried out to gather a collection of data extracted from several studies about the snake Lachesis muta muta(surucucu),encompassing in this information from the effects and properties of its venom,case report,treatment and even diagnosis.L.m.muta was addressed throughout the study by referring mainly to their venom,which in isolated fractions,as LHFI,LHFII,LmTX-I,among others,present several activities,among which stand out are:coagulant,hemorrhagic,proteolytic and neurotoxic.Besides,other studies involving its diagnosis,treatment,cytotoxicity,edema,inflammation,genotoxicity and mutagenicity have also been carried out.The bibliographic survey initially made,followed by the selection of collected data,was properly organized in the text using the narrative method,so that the findings could be chronologically distributed in a timeline.Therefore,it was possible to conclude that all these studies were and are of paramount importance to help understand the pathophysiology of envenoming by this snake,in addition to pointing out the Bothrops-Lachesis antivenom,opening a wide therapeutic window for numerous applications.展开更多
Context: Anesthetic tubes are always on the surgical table, for this reason, it's necessary to perform its disinfection, generally by chemicals. Aim: Was to analyze the effectiveness of tubes decontamination made b...Context: Anesthetic tubes are always on the surgical table, for this reason, it's necessary to perform its disinfection, generally by chemicals. Aim: Was to analyze the effectiveness of tubes decontamination made by disinfectant substances used in a clinical setting and to identify the microorganisms found on their surface. Materials and Methods: 14 anesthetic tubes were collected from dental clinic, on 5 groups. 01 plastic and 01 glass tubes that were not submitted to any disinfection process composed the control group and they had been sown in Agar Blood. Experimental groups underwent immersion and fixation with the proposed chemicals for 1 minute, laminar flow hood was used to seed it in Agar Blood and then it was transferred to incubator for 24 hours at 37℃. Tests were used to identify the main Gram positive pathogenic genera. Gram-negative pathogenic colonies isolated were seeded in biochemical means of identification. Results: It was possible to identify the presence of Staphylococcus coagulase negative, Staphylococcus aureus, Streptococcus viridans, Staphylococcus saprophyticus, Escherichia coli and Acinetobacter spp, as well as the effectiveness of chemical solutions proposed in this study. Conclusions: All chemical solutions proposed in this study were effective for the surface disinfection process of anesthetic tubes.展开更多
基金thank Fundação de AmparoàPesquisa do Estado de São Paulo(FAPESP,Grant No.2019/21147-6)for fellowship.
文摘This article was carried out to gather a collection of data extracted from several studies about the snake Lachesis muta muta(surucucu),encompassing in this information from the effects and properties of its venom,case report,treatment and even diagnosis.L.m.muta was addressed throughout the study by referring mainly to their venom,which in isolated fractions,as LHFI,LHFII,LmTX-I,among others,present several activities,among which stand out are:coagulant,hemorrhagic,proteolytic and neurotoxic.Besides,other studies involving its diagnosis,treatment,cytotoxicity,edema,inflammation,genotoxicity and mutagenicity have also been carried out.The bibliographic survey initially made,followed by the selection of collected data,was properly organized in the text using the narrative method,so that the findings could be chronologically distributed in a timeline.Therefore,it was possible to conclude that all these studies were and are of paramount importance to help understand the pathophysiology of envenoming by this snake,in addition to pointing out the Bothrops-Lachesis antivenom,opening a wide therapeutic window for numerous applications.
文摘Context: Anesthetic tubes are always on the surgical table, for this reason, it's necessary to perform its disinfection, generally by chemicals. Aim: Was to analyze the effectiveness of tubes decontamination made by disinfectant substances used in a clinical setting and to identify the microorganisms found on their surface. Materials and Methods: 14 anesthetic tubes were collected from dental clinic, on 5 groups. 01 plastic and 01 glass tubes that were not submitted to any disinfection process composed the control group and they had been sown in Agar Blood. Experimental groups underwent immersion and fixation with the proposed chemicals for 1 minute, laminar flow hood was used to seed it in Agar Blood and then it was transferred to incubator for 24 hours at 37℃. Tests were used to identify the main Gram positive pathogenic genera. Gram-negative pathogenic colonies isolated were seeded in biochemical means of identification. Results: It was possible to identify the presence of Staphylococcus coagulase negative, Staphylococcus aureus, Streptococcus viridans, Staphylococcus saprophyticus, Escherichia coli and Acinetobacter spp, as well as the effectiveness of chemical solutions proposed in this study. Conclusions: All chemical solutions proposed in this study were effective for the surface disinfection process of anesthetic tubes.