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The 5 Hallmarks of Biomaterials Success: An Emphasis on Orthopaedics
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作者 Dustin L. Williams Brad M. Isaacson 《Advances in Bioscience and Biotechnology》 2014年第4期283-293,共11页
Over the past 200 years, there has been significant advancements in the fields of bioengineering and orthopaedics. Investigators, clinicians and manufactures are learning that the success of implant systems is not lim... Over the past 200 years, there has been significant advancements in the fields of bioengineering and orthopaedics. Investigators, clinicians and manufactures are learning that the success of implant systems is not limited to a single factor, but a combination of variables that must work in unison to provide stability and high survivorship. Innovations continue to advance these fields and include: biomimetic alterations, three-dimensional, patient-specific reconstructions and novel coatings to mitigate aseptic loosening or other pathologies. However, implant systems continue to fail in clinical practice since they do not adhere to key fundamental principles. Therefore, this article is intended to highlight 5 hallmarks of biomaterials that should be considered during design, surgery, and post-operative rehabilitation. 展开更多
关键词 BIOMATERIALS ORTHOPAEDICS IMPLANT Bone BIOFILM
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