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仰韶文化人类遗骸古DNA的初步研究 被引量:6
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作者 赖旭龙 杨淑娟 +6 位作者 唐先华 施苏华 李润权 杨洪 高强 李涛 盛桂莲 《地球科学(中国地质大学学报)》 EI CAS CSCD 北大核心 2004年第1期15-20,共6页
近 2 0年来 ,古DNA研究技术和方法已迅猛发展 .目前从古人类残骸中获取DNA序列 ,进而讨论人类的演化、亲缘关系和迁移成为分子人类学的一个重要方向 .本研究对采自陕西临潼仰韶文化 6 0 0 0多年前的姜寨遗址第一期和第二期文化层中的古... 近 2 0年来 ,古DNA研究技术和方法已迅猛发展 .目前从古人类残骸中获取DNA序列 ,进而讨论人类的演化、亲缘关系和迁移成为分子人类学的一个重要方向 .本研究对采自陕西临潼仰韶文化 6 0 0 0多年前的姜寨遗址第一期和第二期文化层中的古人类残骸进行古DNA提取、扩增和测序 ,获得了 16 9bp的线粒体高变控制区Ⅰ的古DNA片段 ,与现代西安人同源性序列有 2个位点的突变 .另外 ,通过在不同实验室进行重复性实验和系统发育分析等方法详细地论证了所获得的DNA序列的可靠性 .在所研究的 6个姜寨遗址样品中有 3个样品获得古DNA序列 ,古DNA的提取成功率为 5 0 % ,高于一般的古DNA研究材料的提取率 ,说明姜寨遗址的人类残骸是研究古DNA的理想材料 ,为今后从分子水平上研究姜寨遗址及其他同地区仰韶文化遗址的古人类墓葬及中国古人类分子演化关系奠定了基础 . 展开更多
关键词 考古 仰韶文化 姜寨遗址 古DNA 可靠性分析 人类遗骸
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Rectangularisation Issues in Health Economics &Insurance: Measures and Mitigations
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作者 S. Jayaprakash P. K. Dinakar +4 位作者 Michael Ha Zhengjun Jiang Uthit Siriwan Manning Li Chukwuemeka Okeagu 《Journal of Applied Mathematics and Physics》 2016年第7期1327-1335,共10页
Aim: Actuaries are financial engineers who construct arrays of risk models combining mathematical techniques in order to carry out required actuarial calculations, such as reserve valuation and pricing. The main purpo... Aim: Actuaries are financial engineers who construct arrays of risk models combining mathematical techniques in order to carry out required actuarial calculations, such as reserve valuation and pricing. The main purpose is to identify some reliable models which price risk factors embedded in insurance products. Health insurance products which are very different in nature from life insurance products must be examined and priced carefully. This paper discusses predominantly two risks. Excess claims ratio and Rectangularisation risks. Background: The first author, Dr. S. Jayaprakash was responsible for Enterprise Risk Management with MetLife India. He was earlier associated with Life Insurance Corporation of India & Oracle Financial Services. Dr. P. K. Dinakar, the second author, qualified as Fellow of the Institute of Actuaries of India, was Chief Actuary of MetLife India Insurance. He was earlier associated with Life Insurance Corporation of India & Birla Sunlife. The third author, Dr. Michael Ha, FSA, MAAA, CFA, CPA (Australia), FRM, PRM, LLM, was Vice President of Strategic Business Initiatives Units at ING Life Insurance in its Taiwan operation. He started his actuarial career at MetLife, Canada. Earlier, the first and third authors worked on a research paper titled “Modeling Policyholder Behavior through Insurance Resonant Marts for Pricing Options and Guarantees” [1] which was presented at the 5th World Congress on Engineering and Technology. The seven authors decided to collaborate on the current research paper for health insurance design and financing purposes. 展开更多
关键词 Claims Ratio VALUATION De-Risk Rectangularisation MORBIDITY
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