烧伤后引起低钙血症的原因分析及临床意义

烧伤后很多原因会引起较为顽固的低钙血症。而钙是人体内最重要的元素之一,是机体各项生理活动不可缺少的离子,参与一切生命活动过程,维系着细胞的正常生理功能。本文对钙的生理功能,缺钙的严重后果以及烧伤后低钙血症的病因进行分析总结,以求引起重视并提示临床需要进行综合性治疗。

Acute electrical injury: A systematic review

Objective: To review low-voltage, high-voltage and lightening electrical burns in adults and children, identify novel areas that are not recognized and improve treatments results and outcome. Methods: An extensive literature search on electrical burn injuries was performed using Ovid Medline, PubMed and Embase databases from 1976 to 2016. Studies related to electrical injury in the adult and children (< 15 years of age) population were included in our study. Fifty-one research papers and review articles were identified and included in this study. Results: Total occurrence of electrical injury among burn injuries ranged from 3.5% to 15.0%. Most of them were low voltage (73%) and one fourth were high voltage and percentage of lightening injuries were very low around 2%–4% of total cases of electrical injury. Mortality is somehow higher among high voltage electrical injuries and lightening. Most of complications of them were morbid in kidney, heart, extremities (including amputations) and nervous systems. Long-term psychological problems were reported with greater incidence rates in high-voltage injuries. Psychological and posttraumatic stress disorders were also reported. Mortality rates from electrical injuries were 2.6% in low voltage and 5.2% in high voltage. Conclusions: High-voltage injury leads to greater morbidity and mortality than low-voltage one. Lightening has mortality of about 32%, higher rates of complications and specialty long-term complications. Strict multi-specialty treatment and rehabilitations are required for proper treatment of electrical injuries.

Epidemiologic and clinical characteristics of severe burn patients: results of a retrospective multicenter study in China, 2011–2015

Background: Severe burns injury is a serious pathology, leading to teratogenicity and significant mortality, and it also has a long-term social impact. The aim of this article is to describe the hospitalized population with severe burns injuries in eight burn centers in China between 2011 and 2015 and to suggest future preventive strategies. Methods: This 5-year retrospective review included all patients with severe burns in a database at eight institutions. The data collected included gender, age, month distribution, etiology, location, presence of inhalation injury, total burn surface area, depth of the burn, the length of hospitalization, and mortality. SPSS 19.0 software was used to analyze the data. Results: A total of 1126 patients were included: 803 (71.3%) male patients and 323 (28.7%) female patients. Scalds were the most common cause of burns (476, 42.27%), followed by fire (457, 40.59%). The extremities were the most frequently affected areas, followed by the trunk. The median length of hospitalization was 30 (15, 52) days. The overall mortality rate was 14.21%. Conclusions: Although medical centers have devoted intensive resources to improving the survival rates of burn patients, expenditures for prevention and education programs are minimal. Our findings suggest that more attention should be paid to the importance of prevention and the reduction of injury severity. This study may contribute to the establishment of a nationwide burn database and the elaboration of strategies to prevent severe burns injury.

Concept analysis of coping with multiple sclerosis

Objective:The concept of coping with disease appears frequently in the literature;however,there is no precise definition of coping.The aim of this study is to clarify coping concept,and to identify its attributes,antecedents,and consequences in patients with multiple sclerosis.Methods:Rodgers'evolutionary method of concept analysis was used to clarify the concept of coping.A literature review was conducted with key terms‘multiple sclerosis’,‘coping’,‘adjustment’,and‘deal with’.After searching databases,1370 papers were found for the period 1995e2017.Finally,55 articles and texts were selected for analysis.Data analysis was carried out using thematic analysis.An independent researcher checked the process to ensure credibility and reduce personal bias.Results:Coping with multiple sclerosis is a multidimensional concept with three main attributes:maintenance of emotional balance,acceptance of the disease,and self-regulation.Social support,awareness toward the disease,attitude toward the disease,and religious-spiritual beliefs were found as antecedents.Health promotion,adherence to treatment regimen,independence in personal life and social relationships,and improvement of family relationships were found as consequences of these attributes.Conclusion:These findings not only add to the body of knowledge in health science,but also serve as an important motivation for further theory development and research in this context.Nurses and health professions can also benefit from a deeper understanding of coping concept in providing and planning healthcare for these patients.

Microorganism-derived biological macromolecules for tissue engineering

According to literature,certain microorganism productions mediate biological effects.However,their beneficial characteristics remain unclear.Nowadays,scientists concentrate on obtaining natural materials from live creatures as new sources to produce innovative smart biomaterials for increasing tissue reconstruction in tissue engineering and regenerative medicine.The present review aims to introduce microorganism-derived biological macromolecules,such as pullulan,alginate,dextran,curdlan,and hyaluronic acid,and their available sources for tissue engineering.Growing evidence indicates that these materials can be used as biological material in scaffolds to enhance regeneration in damaged tissues and contribute to cosmetic and dermatological applications.These natural-based materials are attractive in pharmaceutical,regenerative medicine,and biomedical applications.This study provides a detailed overview of natural-based biomaterials,their chemical and physical properties,and new directions for future research and therapeutic applications.