Cyclophilin A(CypA,encoded by PPIA)is a peptidyl-prolyl cis/trans isomerase(PPIase)that is expressed ubiquitously in all type of cells.CypA is the major cellular target for the immunosuppressive drug cyclosporin A(CsA...Cyclophilin A(CypA,encoded by PPIA)is a peptidyl-prolyl cis/trans isomerase(PPIase)that is expressed ubiquitously in all type of cells.CypA is the major cellular target for the immunosuppressive drug cyclosporin A(CsA)and is involved in protein folding,cell signaling,inflammation,and tumorigenesis.Recent work suggests that it展开更多
基金supported by grants from the National Natural Science Foundation of Chinathe Key Research Program of the Chinese Academy of Sciencesthe National Key Technology Support Program
文摘Cyclophilin A(CypA,encoded by PPIA)is a peptidyl-prolyl cis/trans isomerase(PPIase)that is expressed ubiquitously in all type of cells.CypA is the major cellular target for the immunosuppressive drug cyclosporin A(CsA)and is involved in protein folding,cell signaling,inflammation,and tumorigenesis.Recent work suggests that it
