Dear Editor,Metabolically induced cancer heterogeneity creates a large source of novel potential targets towards an enhanced therapeutic window alone and in combination with classic chemo-and radiotherapy[1,2].This is...Dear Editor,Metabolically induced cancer heterogeneity creates a large source of novel potential targets towards an enhanced therapeutic window alone and in combination with classic chemo-and radiotherapy[1,2].This is of particular interest for non-small cell lung cancer(NSCLC),which accounts for more than 80%of all lung tumor types characterized by limited responses to current treatment options[3–5].展开更多
We describe a fiber optic hydrophone array system that could be used for underwater acoustic surveillance applications (e.g. military, counter terrorist, and customs authorities in protecting ports and harbors), off...We describe a fiber optic hydrophone array system that could be used for underwater acoustic surveillance applications (e.g. military, counter terrorist, and customs authorities in protecting ports and harbors), offshore production facilities or coastal approaches as well as various marine applications. In this paper, we propose a new approach to underwater sonar systems using the voltage-controlled liquid crystals and simple multiplexing method. The proposed method permits measurement of sound under water at multiple points along an optical fiber using the low cost components and standard single mode fiber, without complex interferometric measurement techniques, electronics or demodulation software.展开更多
基金supported by the Swiss National Science Foundation,Switzerland(grant 320030_176088 to Johannes Häberle)the Wolfermann-Nägeli-Stiftung,Switzerland(grant 2020/28 to Martin Pruschy).+2 种基金supported by the Research Council of Norway(NOR-OPENSCREEN 245922/F50)supported by The Fundación Ramón Areces(grant CIVP20A6610)supported by a grant from European Union’s Framework Program for Research and Innovation Horizon 2020(2014-2020)under Marie Skłodowska-Curie(Grant Agreements No.860245)(ITN THERADNET)to Marvin Kreuzer and Martin Pruschy.
文摘Dear Editor,Metabolically induced cancer heterogeneity creates a large source of novel potential targets towards an enhanced therapeutic window alone and in combination with classic chemo-and radiotherapy[1,2].This is of particular interest for non-small cell lung cancer(NSCLC),which accounts for more than 80%of all lung tumor types characterized by limited responses to current treatment options[3–5].
文摘We describe a fiber optic hydrophone array system that could be used for underwater acoustic surveillance applications (e.g. military, counter terrorist, and customs authorities in protecting ports and harbors), offshore production facilities or coastal approaches as well as various marine applications. In this paper, we propose a new approach to underwater sonar systems using the voltage-controlled liquid crystals and simple multiplexing method. The proposed method permits measurement of sound under water at multiple points along an optical fiber using the low cost components and standard single mode fiber, without complex interferometric measurement techniques, electronics or demodulation software.