CHM Season's Greetings:Perspectives in 2014

Chinese HerbalMedicines （CHM） was initially founded in 2009. Our child is now five years old. We are grateful for the efforts of everyone who supports the journal. Since its foundation, the papers published in CHM have been indexed in many databases, including UPD, IC, CAS, CAB Abstracts, Global Health, EM and BASE. In September 2013, the Institute of Science and Technical Information of China announced that CHM had been selected as one of the Source Journals for Chinese Scientific and Technical Papers and Citations.

基于主元分析的传感器故障检测盲区预测

传感器故障极易发生但不易察觉,其测量数据是制冷空调系统安全运行和优化节能的必要条件。分析了以Q统计量为故障检测边界的基于主元分析的传感器故障检测流程,建立了一种预测传感器故障检测能力的指标——故障检测盲区,用于预测训练数据集中各个传感器的故障检测能力,从而分析、评价和优化建模用训练数据的质量。采用工程数据、实验数据分别开展算法验证,结果表明故障检测盲区能有效预测选定数据集的相关传感器的故障检测结果。

热喷铝技术在模块化工厂中的应用

简单介绍了热喷铝防腐技术在模块化工厂管廊结构中的应用,分析了施工过程中的一些关键因素,并对热喷铝技术的一些新发展和应用情况提出了见解。

营改增促进现代服务业高质量发展的效应分析

现代服务业在中国经济结构中的作用日益显著,通过税制改革促进现代服务业高质量发展成为社会各界共识。论题以营改增为自然实验构建双重差分模型,检验营改增对现代服务业的影响。结果显示:营改增政策促进了现代服务业的投资规模,使得企业快速成长,形成规模经济效应,从而提高企业的盈利能力。本结论的政策含义在于:通过税制改革,降低企业的营运成本,促进中国经济高质量发展。

Fasting for Laboratory Tests Poses a High Risk of Hypoglycemia in Patients with Diabetes: A Pilot Prevalence Study in Clinical Practice

Objective: Fasting for lipid profiles is a deeply-rooted tradition that is being revisited. In patients with diabetes, such fasting poses a risk of hypoglycemia, as observed in recent studies and case reports. This iatrogenic, overlooked, form of hypoglycemia has been referred to as Fasting-Evoked En-route Hypoglycemia in Diabetes (FEEHD). The objective of the study is to determine the prevalence of FEEHD in clinical practice. Methods: A two-page survey was administered to adults with diabetes on anti-diabetic medication(s). Patients were asked if they recalled having experienced hypoglycemia while fasting for laboratory tests (FEEHD) during the preceding 12 months. Results: Of 168 patients enrolled, 166 completed the survey, with a mean age of 55.3 (SD: 15.4) years. Seventy-nine (47.6%) were females. Of these 166 patients, 119 (71 %) had type 2 diabetes. Forty-five patients (27.1%) reported having experienced one or more FEEHD events. Notably, only 31.1% of the patients who experienced a FEEHD event informed their provider of the event, and only 40% of FEEHD events reportedly resulted in any subsequent provider-made medication change(s) to prevent future events. Conclusions: This is the first study of FEEHD prevalence in clinical practice, the results of which serve to increase awareness amongst clinicians about the occurrence of FEEHD. We believe that FEEHD appears to be overlooked by clinicians. The prevalence of FEEHD in clinical practice is strikingly high (27.1%). More concerning is the significant underreporting of FEEHD events by patients to their clinicians (31%). We hope this study will trigger further investigation to confirm these preliminary findings and modify practice guidelines.

Determination of Quality Markers is Basis for Establishing Quality Standard and Control of Chinese Herbal Medicines

The quality marker is a brand new concept not only for the quality assessment and control of TCMs but also for other herbal medicine systems which shares similar features of multiple components.It is also worth to mention that integration of traditional Chinese medicinal theory with such modern science as natural products chemistry,chromatographic analysis,network pharmacology,systems biology,is essential for the determination and validation of reasonable,scientific,and practical quality markers.

Quality Marker Concept Inspires the Quality Research of Traditional Chinese Medicines

Traditional Chinese medicines （TCMs） have been used in China for thousands of years for the treatment of various diseases, highly treated as the Chinese cultural heritage. It has played the pivotal role in maintaining the health of Chinese people and even the entire globe.

Medicinal Model Plants'Breaking the Traditional Medicine Research Methods

Model organisms are the important part of modem life sciences. Arabidopsis thaliana, Oryza sativa, and other model plants have been widely applied in the field of plant science and agronomy, while the international studies on traditional medicine lack the model organisms. Salvia miltiorrhiza, a perennial herb, is one Of the most commonly used medicines.

Quality study needs innovation

We are coming to the end of 2020. In 2020, we’ve seen our Party, government, doctors, and scientists use traditional Chinese medicine (TCM) products and medical technology in the treatment of the COVID-19 disease, but in new year of 2021, we face a new variant of the disease that requires a new vigilance, we need good drugs and vaccines to control and therapy of COVID-19.

Biopotency Assays, a Model with Integration Feature for Quality Control Research of CMM

As known,the development of quality control（QC）and quality assessment（QA）in the products of Chinese materia medica（CMM）is difficult and challenging.Some of the well-known analysis methods,such as IR,UV,HPLC,NMR GC-MS,and LC-MS have been applied in chemical components of the QC of CMMs and have gained significantimpact and advancement in modern analytical fields.

‘Food and medicine continuum’–Why we should promote cross-cultural communication between the global East and West

It is estimated that by 2030 one sixth of the global population will be aged over 60(WHO,2021).Aging leads to functional decline,which triggers many chronic diseases and geriatrics.It is reported that the elderly often suffer from geriatric syndromes such as frailty,sarcopenia,weight loss and dementia(Sanford et al.,2020);for those aged over 85,conditions of hearing and vision loss,decline in immune function,cardiovascular diseases,osteoporosis and dementia are in high prevalence(Jaul&Barron,2017).Therefore,aging has been an important risk for chronic diseases and geriatrics globally.

Plant Tissue Culture and Biosynthesis Provide a Fast Way to Produce Active Constituents of Traditional Chinese Medicines

The plant kingdom has provided literally thousands of natural products with widely diverse chemical structures and a vast array of biological activities.Many of them have seen subsequent application in discovery of new druids and the pharmaceutical industry and clinical therapeutic application.

Chinmedomics Builds a Bridge from Traditional to Modern Research of Traditional Chinese Medicine

＂Omics＂ is a new research field of integrative systems biology and bioinformatics.In the post genomic era,the core scientific problem is to study the relationship between different ＂omics＂ and functions based on bioinformatics.How to apply the omics method and technology to understand the complexity of traditional Chinese medicines（TCM）is one of the hot spots in the recent decade in China.

Instruction for Authors

Chinese Herbal Medicines（CHM）is an official international journal sponsored by Tianjin Institute of Pharmaceutical Research and Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences.The purpose of CHM is to provide a forum for the studies on Chinese herbal medicines,phytomedicines,and natural products as well.

Instruction for Authors

Chinese Herbal Medicines（CHM）is an official international journal sponsored by Tianjin Institute of Pharmaceutical Research and Institute of Medicinal Plant Development,Chinese Academy of Medical Sciences.The purpose of CHM is to provide a forum for the studies on Chinese herbal medicines,phytomedicines,

Looking forward to the Future to Meet the Challenge: Research for Rhizosphere Microbes and Mocrobiome of Medicinal Plants

Molecular biology covers a wide scope of problems related to molecular and cell biology including structural and functional genomics, transcriptomics, proteomics, bio- informatics, and biomedicines. Molecular biology is the study of molecular underpinnings of the processes of replication, transcription, translation, and cell function. The central dogma of molecular biology where genetic material is transcribed into RNA and then translated into proteins, despite being oversimplified, still provides a good starting point for understanding the field. The picture has been revised in light of emerging novel roles for RNA. Increasingly many other areas of biology focus on molecules, either directly or indirectly studying the interactions in their own right. The techniques and methods of molecular biology, such as molecular cloning, polymerase chain reaction, gel electrophoresis, macromolecule blotting and probing, microarray and so on, have been applied in biomedicine and herbal medicines.

Herbal Medicine Belongs to Not Only the Nationality, But Also the World

On the view point of herb research in the world traditional medicines, Digeda is used to vary the plants originated from different species and families, such as India Digeda （Hurghada） is Swertie chirayita （Buch. -Ham.）, Nepal Digeda （Hurghada） is Swertia cliete. Tibetan Digeda （Geda） are Saxifrage umbellulate Hook. f. ＆Thoms. and 5axifraga umbelluleta Hook. f. ＆Thoms. var. pectinata （C. Marq. ＆ Airy-Shaw） J. T. Pan. Alatan Digeda （Hurghada） is Saxifrage unguiculata Engl. Menken Digeda （Hurghada） now differs greatly. In Mongolia, Mongolian doctors use Parnassia palustris as the Digeda; Gisborne to Hurghada （Sandinista） are Swertia erythrosticta and Gentiana Ioureirii. Temuco uses Swertia pseudochineis as Digeda （Baghdad）. In Inner Mongolia Autonomous Region of China, Mongolian medicine Digeda is mainly originated from the three kinds of medicinal plants in Gentianaceae, Swertie pseudochinensis Hara, Gentianopsis barbata Froel Ma, and Lomatogonium rotetwn （L.） Friesex Nym. Additionally, in Inner Mongolia and Tibetan Autonomous Regions of China, the used Digeda is different from Inner Mongolia fork Medicine, Parnassia palustris and P. orepohila, Tibetan fork medicine is different from G. gilvostriata Flat Lei, G. barbara and G. paludosa. Halenia sibirica is recorded in Inner Mongolian Medicine 5tanderds. Therefore, herbal medicine Digede belongs to not only the nationality, but also the world.

Scientific and Practical Bio-analysis Method is Basic for TCM Pharmacokinetic Study

Traditional Chinese medicine （TCM） has an ancient history and unique system, including theory, methodology, prescription, formulation and medicines. There are differences between TCM and chemical drugs. For TCM, the multiple components in vivo are possibly to be detected; the number of components is relatively restricted; they could represent the therapeutic effect of the parent recipe; the concentrations and pharmacokinetics （PK） could affected by the combination of traditional medicines in recipe; the effects of new bioactive compounds （metabolites） related with those of their recipe; and the PK can be affected by body state in TCM treatment significantly. Therefore, the difficulty and challenge are far greater in PK study of TCMs than the chemical drugs.

Ethical Guideline to Authors,Editors,and Reviewers

Drug products are specific goods with safety and effectiveness in medical health case.All of researchers（authors）,reviewers,and editors must abide by medical ethical obligation,and also must deter to the ethical obligation for publication.

Systems Biology Strategy in Chinese Materia Medica Research

Current pharmaceutical research has realized that the conventional principles in drug discovery might have some oversights. These included that many drugs were previously believed to bind exclusively to a single target, actually interact with multiple targets, and only in such way it could take effect （Dar et al, 2012）.