The eye is an important organ,it provides vision and it is an important component of our facial identity(1,2).There is an old saying“The eye is the window of the soul”,clear and bright eyes bring esthetic pleasure t...The eye is an important organ,it provides vision and it is an important component of our facial identity(1,2).There is an old saying“The eye is the window of the soul”,clear and bright eyes bring esthetic pleasure to people.Human eye is globular and consists of two main parts,the anterior and posterior segments(1,2).Although the posterior part of the eye is comfortably located in the orbit,they are delicate because its anterior segment including the cornea is exposed to the outside world,thus accessible to wear and tear.To protect and maintain the eye functions while reduce the disruptions from outside and inside the body,the eyes are equipped with defense mechanisms for both the anterior and posterior segments(1,2).展开更多
In traditional cancer therapy, including chemo and radiation therapy, the goal is always to kill as much cancer cells as possible. However, the truth is that it is difficult to kill 100% of the cancer cells for these ...In traditional cancer therapy, including chemo and radiation therapy, the goal is always to kill as much cancer cells as possible. However, the truth is that it is difficult to kill 100% of the cancer cells for these therapies and the remaining cells often leads to relapse. So the million-dollar question is, how to eliminate the majority of the remaining cancer cells so that the disease can be manageable in a clinical setting. Currently the best approach that is attracting much attention is cancer immune therapy and excit- ing developments in this field have led to cure in some cases that is unimaginable before [1]. There are two major parts to cancer immune therapy that need to work together to make the therapy successful. One is on the reversal of immune suppressive microen- vironment in cancer to allow the immune cells to target the tumor.展开更多
基金This work was primarily supported by the National Institute of Environmental Health Sciences(NIEHS)R01 ES016746 and ES022698 as well as U01 ES027237with leveraged support from the National Science Foundation(NSF)and the Environmental Protection Agency(EPA)under Cooperative Agreement Number DBI 0830117 and 1266377Additional support is from“Hundred Talents Program”of Chinese Academy of Sciences and National Natural Science Foundation of China(31570899).
文摘The eye is an important organ,it provides vision and it is an important component of our facial identity(1,2).There is an old saying“The eye is the window of the soul”,clear and bright eyes bring esthetic pleasure to people.Human eye is globular and consists of two main parts,the anterior and posterior segments(1,2).Although the posterior part of the eye is comfortably located in the orbit,they are delicate because its anterior segment including the cornea is exposed to the outside world,thus accessible to wear and tear.To protect and maintain the eye functions while reduce the disruptions from outside and inside the body,the eyes are equipped with defense mechanisms for both the anterior and posterior segments(1,2).
文摘In traditional cancer therapy, including chemo and radiation therapy, the goal is always to kill as much cancer cells as possible. However, the truth is that it is difficult to kill 100% of the cancer cells for these therapies and the remaining cells often leads to relapse. So the million-dollar question is, how to eliminate the majority of the remaining cancer cells so that the disease can be manageable in a clinical setting. Currently the best approach that is attracting much attention is cancer immune therapy and excit- ing developments in this field have led to cure in some cases that is unimaginable before [1]. There are two major parts to cancer immune therapy that need to work together to make the therapy successful. One is on the reversal of immune suppressive microen- vironment in cancer to allow the immune cells to target the tumor.
