Patients with cancer are at increased risk of SARA-CoV-2 infection or developing severe COVID-19 cases due to malignancy or immunosuppressive therapy,but they are generally excluded from the target population for COVI...Patients with cancer are at increased risk of SARA-CoV-2 infection or developing severe COVID-19 cases due to malignancy or immunosuppressive therapy,but they are generally excluded from the target population for COVID-19 vaccination.In general,inactivated vaccines are safe and immunogenic for patients with cancer,but live attenuated vaccines are not recommended.The study suggested that the safety of the mRNA COVID-19 vaccine in patients with cancer is similar to that in healthy people,but immunogenicity is slightly weaker,and a booster dose may be needed.This paper aims to summarize the results of COVID-19 vaccine clinical studies conducted in patients with cancer worldwide and the relevant guidelines released by authorities,so as to provide evidence for promoting COVID-19 vaccination for patients with cancer.展开更多
文摘Patients with cancer are at increased risk of SARA-CoV-2 infection or developing severe COVID-19 cases due to malignancy or immunosuppressive therapy,but they are generally excluded from the target population for COVID-19 vaccination.In general,inactivated vaccines are safe and immunogenic for patients with cancer,but live attenuated vaccines are not recommended.The study suggested that the safety of the mRNA COVID-19 vaccine in patients with cancer is similar to that in healthy people,but immunogenicity is slightly weaker,and a booster dose may be needed.This paper aims to summarize the results of COVID-19 vaccine clinical studies conducted in patients with cancer worldwide and the relevant guidelines released by authorities,so as to provide evidence for promoting COVID-19 vaccination for patients with cancer.
