Developmental and epileptic encephalopathies(DEEs)are neurological disorders generally involving medically intractable seizures and a diverse array of comorbid neuropsychiatric delays and deficits that may severely af...Developmental and epileptic encephalopathies(DEEs)are neurological disorders generally involving medically intractable seizures and a diverse array of comorbid neuropsychiatric delays and deficits that may severely affect cognition,mood,sleep,social behavior,movement control,learning,and/or memory.Dravet syndrome(DS),also known as Severe Myoclonic Epilepsy of Infancy.展开更多
Learning and memory are fundamental brain functions affected by dietary and environmental factors. Magnesium is essential for maintaining normal body and brain functions. Here,
A miniature two-photon microscope circumvents previous limitations of this technology and now allows imaging of activity not only in the soma but also in the dendrites and spines of neurons in freely moving animals en...A miniature two-photon microscope circumvents previous limitations of this technology and now allows imaging of activity not only in the soma but also in the dendrites and spines of neurons in freely moving animals engaged in a wide spectrum of behaviors.Conventional brain imaging in animal models with multiphoton microscopy usually requires that the animal has its head fixed to a very large table microscope,which severely limits the types of behaviors that can be studied.展开更多
基金supported by Dravet Syndrome Foundation,NIH/NINDS R01-NS112500.
文摘Developmental and epileptic encephalopathies(DEEs)are neurological disorders generally involving medically intractable seizures and a diverse array of comorbid neuropsychiatric delays and deficits that may severely affect cognition,mood,sleep,social behavior,movement control,learning,and/or memory.Dravet syndrome(DS),also known as Severe Myoclonic Epilepsy of Infancy.
文摘Learning and memory are fundamental brain functions affected by dietary and environmental factors. Magnesium is essential for maintaining normal body and brain functions. Here,
文摘A miniature two-photon microscope circumvents previous limitations of this technology and now allows imaging of activity not only in the soma but also in the dendrites and spines of neurons in freely moving animals engaged in a wide spectrum of behaviors.Conventional brain imaging in animal models with multiphoton microscopy usually requires that the animal has its head fixed to a very large table microscope,which severely limits the types of behaviors that can be studied.
