In a recent paper in Science,Bruchez et al.1 provide new insights how host cells can fight virus infection.They show that an MHC class II transactivator(CIITA)—which normally operates as part of the interferon(IFN)-s...In a recent paper in Science,Bruchez et al.1 provide new insights how host cells can fight virus infection.They show that an MHC class II transactivator(CIITA)—which normally operates as part of the interferon(IFN)-stimulated immune response—is also involved in an antiviral response,beyond its well-known function of antigen presentation.展开更多
基金supported by the“Excellence Initiative—Research University”program at the Nicolaus Copernicus UniversityK.P.is supported by the subsidy from the Polish Ministry of Science and Higher Education for the research on the SARS-CoV-2 and a grant from the National Science Center UMO-2017/27/B/NZ6/02488C.S.v.B.is supported by grant GM103554 from the National Institutes of Health.
文摘In a recent paper in Science,Bruchez et al.1 provide new insights how host cells can fight virus infection.They show that an MHC class II transactivator(CIITA)—which normally operates as part of the interferon(IFN)-stimulated immune response—is also involved in an antiviral response,beyond its well-known function of antigen presentation.
