Chronic inflammatory lung disease is a common ,health problem and often treated with potent antibiotics, anti-tuberculosis drugs, and antifungal agents. However, in case of medical therapy failure, surgical treatment ...Chronic inflammatory lung disease is a common ,health problem and often treated with potent antibiotics, anti-tuberculosis drugs, and antifungal agents. However, in case of medical therapy failure, surgical treatment has been often considered as an effective procedure. Indications for surgical procedure mainly include recurrent infection, acute suppurative complications including lung abscess and empyema, and often chronic, intermittent, or massive hemoptysis.1 Segmentectomy or lobectomy is considered as an ＂ideal＂ procedure when the disease is localized to one lung and single segment or lobe.展开更多
Hereditary complement deficiencies are usually associated with increased susceptibility to infections and/ or autoimmune diseases. Generally, they are rare： the majority have been detected in no more than a few dozen...Hereditary complement deficiencies are usually associated with increased susceptibility to infections and/ or autoimmune diseases. Generally, they are rare： the majority have been detected in no more than a few dozen individuals. However, due to lack of population-based studies, such cases are usually detected by chance, e.g., in severely ill persons and their family members. An exception is mannan-binding lectin （MBL） deficiency, affecting perhaps 5%-10% of the population. MBL, like collectin-10, -11 and the ficolins （M-, L-, H-）, is a pattern-recognition molecule, cooperating with MBL- associated serine proteases （MASPs） in the initiation of complement activation via the lectin pathway. In contrast, deficiency展开更多
文摘Chronic inflammatory lung disease is a common ,health problem and often treated with potent antibiotics, anti-tuberculosis drugs, and antifungal agents. However, in case of medical therapy failure, surgical treatment has been often considered as an effective procedure. Indications for surgical procedure mainly include recurrent infection, acute suppurative complications including lung abscess and empyema, and often chronic, intermittent, or massive hemoptysis.1 Segmentectomy or lobectomy is considered as an ＂ideal＂ procedure when the disease is localized to one lung and single segment or lobe.
文摘Hereditary complement deficiencies are usually associated with increased susceptibility to infections and/ or autoimmune diseases. Generally, they are rare： the majority have been detected in no more than a few dozen individuals. However, due to lack of population-based studies, such cases are usually detected by chance, e.g., in severely ill persons and their family members. An exception is mannan-binding lectin （MBL） deficiency, affecting perhaps 5%-10% of the population. MBL, like collectin-10, -11 and the ficolins （M-, L-, H-）, is a pattern-recognition molecule, cooperating with MBL- associated serine proteases （MASPs） in the initiation of complement activation via the lectin pathway. In contrast, deficiency
