Background: The use of feed grade amino acids can reduce the cost of lactation feed. With changing genetics,increasing feed costs, and higher number of pigs weaned with heavier wean weights further evaluation of highe...Background: The use of feed grade amino acids can reduce the cost of lactation feed. With changing genetics,increasing feed costs, and higher number of pigs weaned with heavier wean weights further evaluation of higher inclusion levels of feed-grade amino acid in lactation diets than previously published is warranted. Two experiments(Exp.) were conducted to determine the optimal inclusion level of L-lysine HCl to be included in swine lactation diets while digestible lysine levels remain constant across dietary treatments and allowing feed grade amino acids to be added to the diet to maintain dietary ratios relative to lysine to maximize litter growth rate and sow reproductive performance. Furthermore, the studies were to evaluate minimal amino acid ratios relative to lysine that allows for optimal litter growth rate and sow reproductive performance.Results: Exp. 1: Increasing L-lysine HCl resulted in similar gilt feed intake, litter, and reproductive performance.Average litter gain from birth to weaning was 2.51, 2.49, 2.59, 2.43, and 2.65 kg/d when gilts were fed 0.00, 0.075,0.150, 0.225, and 0.30% L-lysine HCl, respectively. Exp. 2: The average litter gain from birth to weaning was 2.68,2.73, 2.67, 2.70, and 2.64 kg/d(P < 0.70) when sows were fed 0.1, 0.2, 0.3, 0.4, and 0.4% L-lysine HCl plus valine,respectively. No other differences among dietary treatments were observed.Conclusions: Collectively, these studies demonstrate corn-soybean meal based lactation diets formulated with a constant SID lysine content for all parities containing up to 0.40% L-lysine HCl with only supplemental feed grade threonine and a methionine source have no detrimental effect on litter growth rate and subsequent total born.展开更多
The compromised egg quality and leg abnormality during the end of the laying cycle(after 40 weeks)have been leading to poor animal welfare and substantial economic losses.Therefore,the effects of fermented calcium(Ca)...The compromised egg quality and leg abnormality during the end of the laying cycle(after 40 weeks)have been leading to poor animal welfare and substantial economic losses.Therefore,the effects of fermented calcium(Ca)butyrate,produced by fermentation by Clostridium butyricum,on production,eggshell quality,and tibial property of hens were explored.A total of 192 Hy-line brown laying hens at50-week-old were assigned to a basal diet or the basal diet with 300 mg/kg of the fermented Ca butyrate from 50 to 58 weeks of age.Each treatment had 6 replicates with 16 hens each.The diet supplemented with 300 mg/kg fermented Ca butyrate notably increased egg weight,ovarian follicle number,and eggshell strength(P=0.072)as compared to the basal diet,which were associated with cytokine secretion,toll-like receptor signaling pathways,and intestinal immunity based on the RNA-seq data from the granulosa.Dietary Ca butyrate inclusion decreased the expression of ileal tumor necrosis factor-alpha and serum pro-inflammatory cytokine concentration,as well as increased the content of serum immunoglobulin A when compared to the basal diet(both P<0.05).The birds that received fermented Ca butyrate diets exhibited higher villus height(P<0.05)and upregulated expression of tight junction proteins,whereas it did not alter the composition of cecal microbiota(P>0.05).In addition,the diet with fermented Ca butyrate reduced the number of osteoclasts in the proximal tibia and the level of C-terminal cross-linked telopeptide of type I collagen,a bone resorption marker(P<0.05),whereas it tended to increase the concentration of the procollagen type I N-terminal propeptide that reflects bone formation marker in serum.Moreover,the layers fed fermented Ca butyrate diets possessed higher(P<0.05)bone area and trabecular number of the proximal tibia,yield load,and ultimate load than those that consumed basal diets.Collectively,dietary fermented Ca butyrate supplementation in post-peak layer diets improved the ovarian function and tibia quality,which might be related to enhancing intestinal integrity and consequently decreasing inflammation mediated bone resorption.展开更多
基金PICAjinomoto HeartlandNovus International listed in the author section fully financially supported this study
文摘Background: The use of feed grade amino acids can reduce the cost of lactation feed. With changing genetics,increasing feed costs, and higher number of pigs weaned with heavier wean weights further evaluation of higher inclusion levels of feed-grade amino acid in lactation diets than previously published is warranted. Two experiments(Exp.) were conducted to determine the optimal inclusion level of L-lysine HCl to be included in swine lactation diets while digestible lysine levels remain constant across dietary treatments and allowing feed grade amino acids to be added to the diet to maintain dietary ratios relative to lysine to maximize litter growth rate and sow reproductive performance. Furthermore, the studies were to evaluate minimal amino acid ratios relative to lysine that allows for optimal litter growth rate and sow reproductive performance.Results: Exp. 1: Increasing L-lysine HCl resulted in similar gilt feed intake, litter, and reproductive performance.Average litter gain from birth to weaning was 2.51, 2.49, 2.59, 2.43, and 2.65 kg/d when gilts were fed 0.00, 0.075,0.150, 0.225, and 0.30% L-lysine HCl, respectively. Exp. 2: The average litter gain from birth to weaning was 2.68,2.73, 2.67, 2.70, and 2.64 kg/d(P < 0.70) when sows were fed 0.1, 0.2, 0.3, 0.4, and 0.4% L-lysine HCl plus valine,respectively. No other differences among dietary treatments were observed.Conclusions: Collectively, these studies demonstrate corn-soybean meal based lactation diets formulated with a constant SID lysine content for all parities containing up to 0.40% L-lysine HCl with only supplemental feed grade threonine and a methionine source have no detrimental effect on litter growth rate and subsequent total born.
基金financially supported by the National Natural Science Foundation of China(31772622)the special fund for young talent in Henan Agricultural University(30501324)
文摘The compromised egg quality and leg abnormality during the end of the laying cycle(after 40 weeks)have been leading to poor animal welfare and substantial economic losses.Therefore,the effects of fermented calcium(Ca)butyrate,produced by fermentation by Clostridium butyricum,on production,eggshell quality,and tibial property of hens were explored.A total of 192 Hy-line brown laying hens at50-week-old were assigned to a basal diet or the basal diet with 300 mg/kg of the fermented Ca butyrate from 50 to 58 weeks of age.Each treatment had 6 replicates with 16 hens each.The diet supplemented with 300 mg/kg fermented Ca butyrate notably increased egg weight,ovarian follicle number,and eggshell strength(P=0.072)as compared to the basal diet,which were associated with cytokine secretion,toll-like receptor signaling pathways,and intestinal immunity based on the RNA-seq data from the granulosa.Dietary Ca butyrate inclusion decreased the expression of ileal tumor necrosis factor-alpha and serum pro-inflammatory cytokine concentration,as well as increased the content of serum immunoglobulin A when compared to the basal diet(both P<0.05).The birds that received fermented Ca butyrate diets exhibited higher villus height(P<0.05)and upregulated expression of tight junction proteins,whereas it did not alter the composition of cecal microbiota(P>0.05).In addition,the diet with fermented Ca butyrate reduced the number of osteoclasts in the proximal tibia and the level of C-terminal cross-linked telopeptide of type I collagen,a bone resorption marker(P<0.05),whereas it tended to increase the concentration of the procollagen type I N-terminal propeptide that reflects bone formation marker in serum.Moreover,the layers fed fermented Ca butyrate diets possessed higher(P<0.05)bone area and trabecular number of the proximal tibia,yield load,and ultimate load than those that consumed basal diets.Collectively,dietary fermented Ca butyrate supplementation in post-peak layer diets improved the ovarian function and tibia quality,which might be related to enhancing intestinal integrity and consequently decreasing inflammation mediated bone resorption.