Alzheimer’s disease(AD)is a chronic neurodegenerative disease,which is difficult to diagnose in its early stages.It is associated with aging and consists of a decline in cognitive functions,memory,and other mental ac...Alzheimer’s disease(AD)is a chronic neurodegenerative disease,which is difficult to diagnose in its early stages.It is associated with aging and consists of a decline in cognitive functions,memory,and other mental activities.Some pathophysiological markers are associated with AD progression and worsening,such as the deposition and intracellular accumulation of senile plaques containing amyloid-β(Aβ)peptides,and tau protein hyperphosphorylation,leading to the formation of neurofibrillary tangles.展开更多
The strategy of expert system for high performance liquid chromatography was discussed, the attentions are mainly placed on the knowledge base for selection of column system, separation modes and detection modes in th...The strategy of expert system for high performance liquid chromatography was discussed, the attentions are mainly placed on the knowledge base for selection of column system, separation modes and detection modes in the analysis of amino acids, peptides and proteins.展开更多
文摘Alzheimer’s disease(AD)is a chronic neurodegenerative disease,which is difficult to diagnose in its early stages.It is associated with aging and consists of a decline in cognitive functions,memory,and other mental activities.Some pathophysiological markers are associated with AD progression and worsening,such as the deposition and intracellular accumulation of senile plaques containing amyloid-β(Aβ)peptides,and tau protein hyperphosphorylation,leading to the formation of neurofibrillary tangles.
基金Project supported by the National Natural Science Foundation of China.
文摘The strategy of expert system for high performance liquid chromatography was discussed, the attentions are mainly placed on the knowledge base for selection of column system, separation modes and detection modes in the analysis of amino acids, peptides and proteins.
