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Genome and epigenome editing identify CCR9 and SLC6A20 as target genes at the 3p21.31 locus associated with severe COVID-19
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作者 Yao Yao Fei Ye +4 位作者 Kailong Li Peng Xu Wenjie Tan Quansheng Feng Shuquan Rao 《Signal Transduction and Targeted Therapy》 SCIE CSCD 2021年第3期602-604,共3页
Dear Editor,The coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a major global health threat.Mortality is predominantly caused by severe respiratory f... Dear Editor,The coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is a major global health threat.Mortality is predominantly caused by severe respiratory failure related to interstitial pneumonia in both lungs and acute respiratory distress syndrome.Recently,genome-wide association studies(GWASs)have identified chromosome 3p21.31(sentinel variant:rsl 1385942)to be associated with both severe and general affected COVID-19 cases. 展开更多
关键词 acute RESPIRATORY DISTRESS
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