The Chinese Journal of Cancer is indexed in Science CitationIndex(SCI) Expanded

On July 22,2014,the Chinese Journal of Cancer(CJC)received a notification from Thomson Reuters that the publications of our journal starting from 2012 have been accepted for coverage in Science Citation Index Expanded,available at the Web of Science,Core Collection,Biological Abstracts,and Biosis Previews.What this means in practical terms is that CJC will receive its first official impact factor(IF)in 2015.This is an important milestone in the history

Award for outstanding contributions to the Chinese Journal of Cancer

At the 4th Guangzhou International Symposium on Oncology,Rui-Hua Xu,Chao-Nan Qian,and Wei Zhang—the chairmen and editors of the Chinese Journal of Cancer—announced and presented awards to 14 authors in recognition of their outstanding contributions to the journal.

The final contest of 2015 Chinese Young Surgeon Contest-surgery for gastric cancer

The final contest of 2015 Chinese Young Surgeon Contest--surgery fur gastric cancer was successfully held in Beijing International Conference Center on 27th June, 2015. After the exciting contest among the 12 finalists, the first prize, Theodor Billroth Prize, was taken by Xian Shen from the First Affiliated Hospital of Wenzhou Medical University in Open Group, and Jian Zhang from Hangzhou First People＇s Hospital in Endoscope Group.

Chinese version of NCCN Clinical Practice Guidelines in Oncology officially authorized by NCCN

The publishing conference of the Chinese version of National Comprehensive Cancer Network （NCCN） Clinical Practice Guidelines in Oncology （hereinafter referred to as NCCN Guidelines） and the inaugural peer reviewer meeting of NCCN Clinical Practice Guidelines in Oncology： Digestive System Cancers （hereinafter referred to as NCCN Guidelines on Digestive System Cancers） were held in People＇s Medical Publishing House in January 28^th, 2016 （Figure 1）.

The 150 most important questions in cancer research and clinical oncology series: questions 6–14

To accelerate our endeavors to overcome cancer,Chinese Journal of Cancer has launched a program of publishing 150most important questions in cancer research and clinical oncology.In this article,nine more questions are presented as followed.Question 6.Why do nasopharyngeal carcinomas rarely metastasize to the brain?Question 7.Can distant spread of cancer cells be blocked by inhibiting the remodeling of high endothelial venules in the sentinel lymph node?Question 8.What sort of live-imaging techniques can be developed to directly observe the dynamic processes of metastasis?Question 9.How does chronic hepatitis prevent liver metastasis from colorectal cancer?Question 10.How many types of host cells contribute to forming the pre-metastatic niche in the lung favorable for metastasis?Question 11.Why do cancers rarely metastasize to the small bowel?Question 12.Why do glioblastomas rarely metastasize outside the central nervous system?Question 13.Despite increased understanding of the molecular genetic events leading to the development and progression of high-grade gliomas,these tumors are the most therapeutically refractory among all human cancers.What then would be the most effective therapeutic approaches to treat what in essence can be regarded as a whole brain malignancy,since even a surgical resection of greater than 99%of tumor tissues is invariably associated with recurrence?Question 14.The blood–brain barrier(BBB)effectively limits a wide variety of potential therapeutic agents from reaching glioma cells widely dispersed in the brain.What therapeutic approaches can be used to breach the BBB and allow therapeutic agents to seek out and kill these tumor cells?

The 150 most important questions in cancer research and clinical oncology series:questions 15-24

To accelerate our endeavors to overcome cancer,Chinese Journal of Cancer has launched a program of publishing 150most important questions in cancer research and clinical oncology.In this article,10 more questions are presented as follows.Question 15:Can tumor-induced erythrogenesis provide qualified red blood cells for carrying oxygen to distant organs?Question 16:Can we overcome tumor resistance to platinum-containing antineoplastic drugs by activating the sensitivity factors in the tumor?Question 17:How can a cancer cell stay dormant for years?Question 18:Why do cancer cells use distinct transcriptomic and proteomic programs to reach the same metastatic phenotype?Question 19:Why do some cancers regress spontaneously?Question 20:What are the regulatory mechanisms occurring in donor cells that determine selective sorting of biological content into vesicles and their biological consequences in recipient cells?Are the genetic transfer and exchange of biological messages between cells transient?Is the phenotypic manipulation of recipient cells temporary or prolonged and persistent?If extracellular vesicles possess immune-modulatory potential,how could they be exploited for immune interventions and cancer immunotherapy?Presumably the cargo of extracellular vesicles reflects the cells of their origin and can be used for cancer diagnosis,how could the uniform/stringent capture criteria be met universally for applying EVs in point-of-care diagnostics for cancer patients?Question 21:Can we use self-sampling technologies to monitor the tumor genetic alterations for more precise targeted therapy?Can we cure a heterogeneous tumor by sequentially targeting the driver molecules?Question 22:Can we postpone the onset of non-infection-related cancers?Question 23:How many types of cells can jointly form the tumor vasculature to provide blood supply for tumor progression?Question 24:How tumor cells transmit their epigenetic features to daughter cells and maintain the malignant phenotype?

The 150 most important questions in cancer research and clinical oncology series:Questions 25–30

To accelerate our endeavors to overcome cancer, Chinese Journal of Cancer has launched a program of publishing 150 most important questions in cancer research and clinical oncology. In this article, 6 more questions are presented as followed. Question 25: Does imprinting of immune responses to infections early in life predict future risk of childhood and adult cancers? Question 26: How to induce homogeneous tumor antigen expression in a heterogeneous tumor mass to enhance the efficacy of cancer immunotherapy? Question 27: Could we enhance the therapeutic effects of immunotherapy by targeting multiple tumor antigens simultaneously or sequentially? Question 28: Can immunotargeting to cytokines halt cancer metastasis? Question 29: How can we dynamically and less-invasively monitor the activity of CD8^+ T killer cells at tumor sites and draining lymph nodes? Question 30: How can the immune system destroy the niches for cancer initiation?

The 150 most important questions in cancer research and clinical oncology series:questions 76-85

Since the beginning of 2017, Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology to promote cancer research and accelerate collaborations. In this article, 10 questions are presented as followed. Question 76. How to develop effective therapeutics for cancer cachexia? Question 77.How can we develop preclinical animal models to recapitulate clinical situations of cancer patients for more effective anti-cancer drug development? Question 78. How can we develop novel effective therapeutics for pancreatic cancer and hepatocellular carcinoma? Question 79. What are the true beneficial mechanisms of antiangiogenic therapy in cancer patients? Question 80. How to approach the complex mechanisms of interplay among various cellular and molecular components in the tumor microenvironment? Question 81. Can tissue oxygenation improve the efficacy of conventional chemotherapy on cancer? Question 82. Can tissue oxygenation improve the efficacy of radiotherapy on digestive system tumors including liver cancer? Question 83. Can we integrate metabolic priming into multimodal management of liver cancer? Question 84. Has the limit of anti-androgen strategy in prostate cancer treatment been reached by the new generation of anti-androgen drugs? Question 85. Can we identify individuals with early-stage cancers via analyzing their clinical and non-clinical information collected from social media, shopping history, and clinical, pathological, and molecular traces?

The 150 most important questionsin cancer research and clinical oncology series:questions 40-49

Since the beginning of 2017,Chinese Journal of Cancer has published a series of important questions in cancer research and clinical oncology,which sparkle diverse thoughts,interesting communications,and potential collaborations among researchers all over the world.In this article,10 more questions are presented as followed.Question 40.Why do mice being used as tumorigenesis models raised in different places or different conditions possess different tumor formation rate? Question 41.How could we generate more effective anti-metastasis drugs? Question 42.What is the molecular mechanism underlying heterogeneity of cancer cachexia in patients with the same pathologic type? Question 43.Will patients with oligo-metastatic disease be curable by immunotherapy plus stereotactic body radiotherapy? Question 44.Can the Warburg effect regulation be targeted for cancer treatment? Question 45.Why do adenocarcinomas seldom occur in the small intestine? Question 46.Is Epstein-Barr virus infection a causal factor for nasal natural killer/T cell lymphoma formation? Question 47.Why will not all but very few human papillomavirusinfected patients eventually develop cervical cancer? Question 48.Why do cervical carcinomas induced by human papilloma virus have a low mutation rate in tumor suppressor genes? Question 49.Can viral infection trigger lung cancer relapse?

The 150 most important questions in cancer research and clinical oncology series:questions 31-39

To accelerate our endeavors to overcome cancer,Chinese Journal of Cancer has launched a program of publishing 150 most important questions in cancer research and clinical oncology.In this article,9 more questions are presented as follows.Question 31:How does aging process inhibit the formation of sarcoma? Question 32:Is intratumoral morphological heterogeneity the consequence of tumor genomic instability or the cause of aggressive tumor behavior?Can we identify more aggressive tumors by computationally analyzing the morphological heterogeneity of the tumor tissues? Question 33:How to pre-surgically differentiate irradiation-induced ulceration from cancerous ulceration? Question 34:Why is epidermal growth factor receptor(EGFR) 19 Del-positive tumor more sensitive to targeted therapy than EGFR 21 L858R-positive tumor in patients with non-small cell lung cancer? Question 35:Can an EpsteinBarr virus vaccine be developed to reduce the incidence of EBV-related malignancies? Question 36:What is the unique feature in sarcoma vasculature that causes the intrinsic resistance of sarcoma against anti-angiogenic therapy?Question 37:How many ways can sarcoma cells protect themselves from the attacks of cytotoxic drugs? Question 38:How stable does the tumor heterogeneity remain along with cytotoxic chemotherapy? Question 39:How to generate a prognostic classifier for diffuse low-grade gliomas by integrating genetic and epigenetic signatures with histological features?

New book Gastric Cancer first launched on the 10^(th) CGCC

The 10th Chinese Gastric Cancer Congress （CGCC） and the 3rd Sunlight Great Wall Cancer Academic Conference, hosted by Chinese Anti-Cancer Association and Beijing Cancer Hospital, was held in Beijing International Conference Center on June 27-28th, 2015. The congress has continued the theme of ＂Standardization, Fusion,

中国癌症研究英文杂志(SCI收录)开通在线投审稿系统

中国癌症研究英文杂志（Chinese Journal of Cancer Research）（ISSN1000-9604,CN11-2591/R）是中国科协主管、中国抗癌协会主办、北京大学临床肿瘤学院（北京市肿瘤防治研究所暨北京肿瘤医院）承办的全英文肿瘤学期刊。本刊被国内外各主要数据库收录，是中国科技核心期刊。

文献管理软件在期刊论文中的应用调查与输出结果分析

【目的】调查文献管理软件在期刊论文中的使用情况,分析文献管理软件处理后的输出结果。【方法】选取英文期刊Chinese Journal of Cancer以及中文期刊《中山大学学报(医学科学版)》和《实用医学杂志》论文,查看是否使用文献管理软件,并分析使用何种软件。对使用EndNote和NoteExpress的论文逐篇按照《中山大学学报(医学科学版)》的文献著录格式,人工核对软件输出结果,提取注意事项。【结果】从上述三种杂志中共收集244篇包含参考文献的已发表论文,其中使用文献管理软件的比例分别为50.0%,35.4%和14.7%。74篇论文使用了文献管理软件,占样本总数的比例为30.3%,其中43篇使用EndNote软件,25篇使用NoteExpress软件。使用两种软件的论文中,英文文献均远多于中文文献,使用EndNote处理的英文文献与中文文献的比例约为10…1,而使用NoteExpress处理的英文文献与中文文献的比例为5…1。未发现国内外作者使用文献管理软件的比例有明显不同。所有论文中的英文文献和中文文献经过软件处理后的输出结果基本符合文献的著录要求,尤其是EndNote输出英文文献的结果。但是,所有论文中的英文文献和中文文献经过软件处理后,输出结果仍然存在格式问题甚至内容错误。【结论】国内医学学术期刊论文中使用文献管理软件的比例偏低,使用文献管理软件的论文的英文文献比例较高。建议国内期刊在稿约时或在网站上增加相关说明条目,建议作者使用参考文献管理软件。虽然软件输出结果较为满意,但是编辑仍然需要再次全面核对把关。