There is a long ritual of acquired immunity using physical exercise, a balanced diet, and pharmaceutical medication to generate immunity against a particular disease insight into the human body. This paper has extensi...There is a long ritual of acquired immunity using physical exercise, a balanced diet, and pharmaceutical medication to generate immunity against a particular disease insight into the human body. This paper has extensively reviewed the impact of exercise, daily life practice, food selection, and several other issues to improve the immune system that combat infection. Studying the effect of exercise in varying degrees on the immunity system of humans is well developed and exhibit in this study. It investigates the prevention of pandemics due to herd immunity and finds the perfect amount of exercise to boost immunity to its maximum. Besides the life practice, it is also explored that vaccination can improve and optimize herd immunity.展开更多
Selective immunoglobulin A deficiency(SIgAD)is considered to be the most common human primary immune-deficiency disease in the world.However,the incidence in China is obviously lower than Caucasian races.The definitio...Selective immunoglobulin A deficiency(SIgAD)is considered to be the most common human primary immune-deficiency disease in the world.However,the incidence in China is obviously lower than Caucasian races.The definition of SIgAD has changed over time with the progress of people’s understanding.The scientific community did not reach a consensus on the definition until 1999.As a result,many previously reported cases need to be excluded under the current definition.SIgAD can lead to several spectra of diseases including infections and autoimmune diseases.We retrospectively summarized the SIgAD patients in Peking Union Medical College Hospital(PUMCH),and summarized the Chinese SIgAD reported in China and abroad in past 40 years.Fourty three SIgAD patients were confirmed in the study,in which 9 were healthy without clinical symptoms.Of the 34 patients with clinical symptoms,recurrent infections were found in 29(85.3%)patients;13(38.2%)patients were with autoimmune diseases;6(17.6%)cases had allergic symptoms;3 patients(8.8%)were with tumors,only one case(2.9%)had a family history.Compared with other countries,sIgAD patients in China showed similar symptoms,but the rate of recurrent infections and autoimmune diseases were higher than some other countries;most of the allergic symptoms are drug allergy,different with the allergic sequelae reported in other countries,such as asthma,rhinitis,food allergy and atopic dermatitis;and it is rare to have family history in Chinese patients.We also figured out that more female SIgAD patients tend to have more autoimmune diseases than men(P=0.039).展开更多
文摘There is a long ritual of acquired immunity using physical exercise, a balanced diet, and pharmaceutical medication to generate immunity against a particular disease insight into the human body. This paper has extensively reviewed the impact of exercise, daily life practice, food selection, and several other issues to improve the immune system that combat infection. Studying the effect of exercise in varying degrees on the immunity system of humans is well developed and exhibit in this study. It investigates the prevention of pandemics due to herd immunity and finds the perfect amount of exercise to boost immunity to its maximum. Besides the life practice, it is also explored that vaccination can improve and optimize herd immunity.
基金CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2M-1-008)The Capital Health Research and Development of Special(2016-2-40114)+1 种基金Public Welfare Scientific Research Project of China(201402012)Golden Brige Engineering Seed Found of Beijing Association for Science and Technology(JQ17032).
文摘Selective immunoglobulin A deficiency(SIgAD)is considered to be the most common human primary immune-deficiency disease in the world.However,the incidence in China is obviously lower than Caucasian races.The definition of SIgAD has changed over time with the progress of people’s understanding.The scientific community did not reach a consensus on the definition until 1999.As a result,many previously reported cases need to be excluded under the current definition.SIgAD can lead to several spectra of diseases including infections and autoimmune diseases.We retrospectively summarized the SIgAD patients in Peking Union Medical College Hospital(PUMCH),and summarized the Chinese SIgAD reported in China and abroad in past 40 years.Fourty three SIgAD patients were confirmed in the study,in which 9 were healthy without clinical symptoms.Of the 34 patients with clinical symptoms,recurrent infections were found in 29(85.3%)patients;13(38.2%)patients were with autoimmune diseases;6(17.6%)cases had allergic symptoms;3 patients(8.8%)were with tumors,only one case(2.9%)had a family history.Compared with other countries,sIgAD patients in China showed similar symptoms,but the rate of recurrent infections and autoimmune diseases were higher than some other countries;most of the allergic symptoms are drug allergy,different with the allergic sequelae reported in other countries,such as asthma,rhinitis,food allergy and atopic dermatitis;and it is rare to have family history in Chinese patients.We also figured out that more female SIgAD patients tend to have more autoimmune diseases than men(P=0.039).
