Acupuncture for erectile dysfunction:a randomized controlled trial

Objective To observe the clinical efficacy of acupuncture in treating erectile dysfunction (ED).Methods A total of 64 ED patients were randomly divided into an acupuncture group (32 cases,2 case dropped out) and a western medication group(32 cases,2 cases dropped out).

Effect of pretreatment of acupuncture on learning-memory ability and related protein of NLRP3 inflammasome in hippocampus in Alzheimer’s disease like rats

Objective To observe the effect of pretreatment of acupuncture on the expression of nucleotide-binding oligomerization domain-like receptor 3 (NLRP3),Caspase-1,interleukin 1 β(IL-1β) and the number of activated microglia (MG) in the hippocampus in Alzheimer’s disease (AD) like rats,so as to explore the mechanism of pretreatment of acupuncture in preventing and treating AD.Methods A total of 36 SD rats were randomly divided into a blank group,a model group and an electroacupuncture (EA) group,12 rats in each group.

Effects of electroacupuncture on NLRP3 inflammasome and pyroptosis protein GSDMD in uterine tissue in rats with primary dysmenorrhea

Objective To observe the effects of electroacupuncture(EA) on NLRP3 inflammasome and its downstream protein gastermin D(GSDMD)in rats with primary dysmenorrhea(PDM),and to explore the potential mechanism of EA on the treatment of PDM.Methods Forty healthy female SD rats without pregnancy were randomly divided into a control group.

Acupuncture combined with western medicine for CP/CPPS: a randomized controlled trial

Objective To compare the clinical efficacy differences among acupuncture combined with western medicine,acupuncture alone and western medicine alone for chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS).Methods Ninety patients were randomly assigned into a needle-medicine group,an

Electroacupuncture at Baliao points for erectile dysfunction after stroke:a randomized controlled trial

Objective To observe theclinical effect of electroacupuncture at Baliao points in patients with erectile dysfunction after stroke.Methods A total of 58 patients with erectile dysfunction after stroke were randomly divided into an observation group(29 cases,1 case dropped off,1 case discontinued)and a control group(29 cases,1 case dropped off).

Clinical observation on electroacupuncture at"four points of sacral region"on moderate to severe stress urinary incontinence after radical prostatectomy

Objective To compare the clinical therapeutic effect between electroacupuncture at"four points of sacral region"and transurethral Erbium laser in treatment of moderate to severe stress urinary incontinence after radical prostatectomy.Methods A total of 68 patients of moderate to severe stress urinary incontinence after radical prostatectomy were divided into an electroacupuncture group(34 cases)and an Erbium laser group(34 cases,3 cases dropped off)according to the settings.

Therapeutic effect of acupuncture combined with medication on chronic prostatitis of damp and heat stasis

Objective To observe the clinical therapeutic effect of electroacupuncture (EA) combined with tamsulosin hydrochloride sustained release capsule on chronic prostatitis (CP) of damp and heat stasis.Methods A total of 70 patients with CP of damp and heat stasis were randomized into an acupuncture plus medication group(35 cases, 4 cases dropped off) and a medication group(35 cases, 5 cases dropped off).

Acupotomy combined withmetformin hydrochloride tablet for type 2 diabetes mellitus and its effect on serum inflammatory factors

Objective To observe the clinical efficacy of acupotomy combined with metformin hydrochloride tablet for type 2 diabetes mellitus(T2DM)and its effect on serum levels of inflammatory factors.Methods A total of 68patientswithT2DMwererandomized intoan acupotomy group(34 cases,2 cases dropped out)and a western medication group(34 cases,2 cases dropped out).Metformin hydrochloride tablet was given orally in the western medication group,0.5-1 g each time,twice a day,for continuous 8 weeks.On the basis of the treatment in the western medication group,acupotomy was applied at bilateral Geshu(BL 17),Weiwanxiashu(EX-B 3),Ganshu(BL 18)in the acupotomy group,once a week for continuous 8 weeks.Before and after treatment,in the two groups,blood glucose(fasting blood glucose[FBC],2-hour plasma glucose[2 h PG]and glycosylated hemoglobin[HbAlc]),TCM syndrome score,blood lipids(total cholesterol[TC],triglyceride[TG],low density lipoprotein cholesterol[LDL-C]and high density lipoprotein cholesterol[HDL-C])。

Effects of moxibustion at"Zusanli"(ST 36)on oxidative stress and intestinal flora in aging rats

Objective To observe the effects of moxibustion at"Zusanli"(ST 36)on oxidative stress and intestinal flora in subacute aging rats,and to explore the possible mechanism of moxibustion in delaying aging.Methods Thirty SD rats were randomly divided into a blank group,a model group and a Zusanli group,with 10 rats in each group.Subacute aging model was established by intraperitoneal injection of D-galactose at dosage of 500 mg/kg in the model group and the Zusanli group,once a day for 42 days.In the Zusanli group,moxibustion was applied at bilateral"Zusanli"(ST 36),once a day,3 moxa cones at each acupoint,for consecutive 28 days.After intervention,the serum levels of superoxide dismutase(SOD)and malondialdehyde(MDA)were detected by ELISA;the intestinal flora was detected by 16S rRNA sequencing technique in each group.

Antioxidative effect of wheat-grain moxibustion on cyclophosphamide-induced liver injury in mice based on Nrf2-Keap1 signaling pathway

Objective To observe the protective effect of wheat-grain moxibustion on cyclophosphamide (CTX)-induced liver injury in mice,and explore its mechanism based on the nuclear factor E2-related factor 2 (Nrf2)-Kelch-like ECH-associated protein 1 (Keap1) signaling pathway.

Intestinal microecology in rats with ulcerative colitis

Objective To study the abundance and diversity ofthe gut flora in rats with dextran sulfate sodium(DSS)-induced ulcerative colitis(UC)to provide new knowledge about the pathogenesis of this disease.Methods

Combined use of Shenmen (HT 7) and Sanyinjiao (SP 6) to improve the anxiety and depression in patients with insomnia:a randomized controlled trial

ObjectiveTo observe the effect of electroacupuncture (EA) at Shenmen (HT 7) and Sanyinjiao (SP 6)on anxiety and depression in patients with insomnia, and to explore the mechanism of its compatibility effect.Methods Ninety patients of insomnia were randomly divided into a combination group, a Shenmen group and a Sanyinjiao group, 30 cases in each group.

Effect of moxibustion on PI3K/Akt/mTOR signaling pathway in foot-pad synovium in rats with rheumatoid arthritis

Objective To observe the effect of moxibustion on phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin protein (PI3K/Akt/mTOR) signaling pathway in the foot-pad synovial tissue in rats with rheumatoid arthritis (RA),and to explore the mechanism of moxibustion for treating RA.

Effect of moxa-cone moxibustion at lung’s back-shu points and front-mu points on Th17/Treg balance in mice with asthma

Objective To observe the effect of moxa-cone moxibustion at lung’s back-shu points and froni-mu points on the expression of helper T lymphocyte 17 (Th 17)/regulatory T lymphocyte (Treg) in mice with asthma,and to explore the possible mechanism of moxa-cone moxibustion on asthma.Methods Sixty SPF-grade healthy male Balb/c mice were randomly divided into a normal group.

Effects of moxibustion of"biaoben acupoint combination"on heart rate variability,atrial natriuretic peptide in the model rats of IBS-D complicated with anxiety

Objective To compare the effects on the heart rate variability(HRV)and the expression of the atrial natriuretic peptide(ANP)in the model rats of irritable bowel syndrome with predominant diarrhea(IBS-D)rats complicated with anxiety between moxibustion of"biaoben acupoint combination"and that of"conventional acupoint combination".Methods Of 50 healthy SPF female SD rats,aged 3 months。