Acupotomy combined withmetformin hydrochloride tablet for type 2 diabetes mellitus and its effect on serum inflammatory factors

Objective To observe the clinical efficacy of acupotomy combined with metformin hydrochloride tablet for type 2 diabetes mellitus(T2DM)and its effect on serum levels of inflammatory factors.Methods A total of 68patientswithT2DMwererandomized intoan acupotomy group(34 cases,2 cases dropped out)and a western medication group(34 cases,2 cases dropped out).Metformin hydrochloride tablet was given orally in the western medication group,0.5-1 g each time,twice a day,for continuous 8 weeks.On the basis of the treatment in the western medication group,acupotomy was applied at bilateral Geshu(BL 17),Weiwanxiashu(EX-B 3),Ganshu(BL 18)in the acupotomy group,once a week for continuous 8 weeks.Before and after treatment,in the two groups,blood glucose(fasting blood glucose[FBC],2-hour plasma glucose[2 h PG]and glycosylated hemoglobin[HbAlc]),TCM syndrome score,blood lipids(total cholesterol[TC],triglyceride[TG],low density lipoprotein cholesterol[LDL-C]and high density lipoprotein cholesterol[HDL-C])。

Effects of moxibustion at"Zusanli"(ST 36)on oxidative stress and intestinal flora in aging rats

Objective To observe the effects of moxibustion at"Zusanli"(ST 36)on oxidative stress and intestinal flora in subacute aging rats,and to explore the possible mechanism of moxibustion in delaying aging.Methods Thirty SD rats were randomly divided into a blank group,a model group and a Zusanli group,with 10 rats in each group.Subacute aging model was established by intraperitoneal injection of D-galactose at dosage of 500 mg/kg in the model group and the Zusanli group,once a day for 42 days.In the Zusanli group,moxibustion was applied at bilateral"Zusanli"(ST 36),once a day,3 moxa cones at each acupoint,for consecutive 28 days.After intervention,the serum levels of superoxide dismutase(SOD)and malondialdehyde(MDA)were detected by ELISA;the intestinal flora was detected by 16S rRNA sequencing technique in each group.

Effects of moxibustion of"biaoben acupoint combination"on heart rate variability,atrial natriuretic peptide in the model rats of IBS-D complicated with anxiety

Objective To compare the effects on the heart rate variability(HRV)and the expression of the atrial natriuretic peptide(ANP)in the model rats of irritable bowel syndrome with predominant diarrhea(IBS-D)rats complicated with anxiety between moxibustion of"biaoben acupoint combination"and that of"conventional acupoint combination".Methods Of 50 healthy SPF female SD rats,aged 3 months。