The human genome contains around 20,000 protein-coding genes and a vast of transcriptional regulatory elements(ENCODE Project Consortium,2012;Roadmap Epigenomics Consortium et al.,2015;Stunnenberg and Hirst,2016).It s...The human genome contains around 20,000 protein-coding genes and a vast of transcriptional regulatory elements(ENCODE Project Consortium,2012;Roadmap Epigenomics Consortium et al.,2015;Stunnenberg and Hirst,2016).It still remains elusive how these regulatory elements regulate their target genes across genomic distances of millions of bases.展开更多
基金supported by the National Natural Science Foundation of China(31900432 to D.L.,31771402 to G.L.)the National Postdoctoral Program for Innovative Talents(BX20180113 to D.L.)+1 种基金China Postdoctoral Science Foundation(2018M640710 to D.L.)the Fundamental Research Funds for the Central Universities(2662018PY025 to G.C.)
文摘The human genome contains around 20,000 protein-coding genes and a vast of transcriptional regulatory elements(ENCODE Project Consortium,2012;Roadmap Epigenomics Consortium et al.,2015;Stunnenberg and Hirst,2016).It still remains elusive how these regulatory elements regulate their target genes across genomic distances of millions of bases.
