Nowadays, dengue fever, a mosquito-borne tropical disease, has become widely distributed in Brazil. In order to prevent such disease, the population of Aedes aegypti mosquito has to be controlled. Then, the aim of thi...Nowadays, dengue fever, a mosquito-borne tropical disease, has become widely distributed in Brazil. In order to prevent such disease, the population of Aedes aegypti mosquito has to be controlled. Then, the aim of this study is to assess the toxicological effects of phenolic compounds against dengue mosquitos. Hence, the larvicidal activity and toxicity of phenolic compounds against Ae. aegypti larvae and A. salina, are evaluated, respectively. The phenolic compounds 2,6-diiodophenol and 4-chloro-2,6-diiodophenol have different toxicity and larvicidal activity. The compound 4-chloro-2,6-diiodophenol shows the highest toxicity for larvae of Ae. aegypti, exhibiting higher toxicity than 2,6-diiodophenol. Although less toxic than Temephos?(organophosphate), the phenolic compounds evaluated by this research, are proved to be effective against Ae. aegypti larvae. This study demonstrates the importance of controlling the dengue mosquito, considering toxicological aspects of phenolic compounds to prevent environmental impacts.展开更多
Acrocomia aculeata (Jacq.) Lodd. shows possibilities for pharmaceutical, food and chemical use. However, its application is limited due to the loss of its bioactive components. Microencapsulation may be an alternative...Acrocomia aculeata (Jacq.) Lodd. shows possibilities for pharmaceutical, food and chemical use. However, its application is limited due to the loss of its bioactive components. Microencapsulation may be an alternative to reduce such problems. A step-by-step optimization approach was used in this work for preservation of bioactive compounds. The applied technique to microencapsulate the Acrocomia aculeata oil was efficient, producing between 64% and 99% of microcapsules and 59% to 97% of encapsulated oil. In the experimental design, temperature was the parameter that significantly influenced the carotenoids of microcapsules. Complex coacervation helped to preserve carotenoids and the antioxidant activity, and an interaction between the temperature and the content was observed for such preservation.展开更多
基金the Brazilian funding agencies CAPES,CNPq/PROCAD 2008,and FUNDECT for financial and fellowship support.
文摘Nowadays, dengue fever, a mosquito-borne tropical disease, has become widely distributed in Brazil. In order to prevent such disease, the population of Aedes aegypti mosquito has to be controlled. Then, the aim of this study is to assess the toxicological effects of phenolic compounds against dengue mosquitos. Hence, the larvicidal activity and toxicity of phenolic compounds against Ae. aegypti larvae and A. salina, are evaluated, respectively. The phenolic compounds 2,6-diiodophenol and 4-chloro-2,6-diiodophenol have different toxicity and larvicidal activity. The compound 4-chloro-2,6-diiodophenol shows the highest toxicity for larvae of Ae. aegypti, exhibiting higher toxicity than 2,6-diiodophenol. Although less toxic than Temephos?(organophosphate), the phenolic compounds evaluated by this research, are proved to be effective against Ae. aegypti larvae. This study demonstrates the importance of controlling the dengue mosquito, considering toxicological aspects of phenolic compounds to prevent environmental impacts.
基金Brazilian Federal Agency for Support and Evaluation of Graduate Education―CAPES for the financial help
文摘Acrocomia aculeata (Jacq.) Lodd. shows possibilities for pharmaceutical, food and chemical use. However, its application is limited due to the loss of its bioactive components. Microencapsulation may be an alternative to reduce such problems. A step-by-step optimization approach was used in this work for preservation of bioactive compounds. The applied technique to microencapsulate the Acrocomia aculeata oil was efficient, producing between 64% and 99% of microcapsules and 59% to 97% of encapsulated oil. In the experimental design, temperature was the parameter that significantly influenced the carotenoids of microcapsules. Complex coacervation helped to preserve carotenoids and the antioxidant activity, and an interaction between the temperature and the content was observed for such preservation.
