Adsorption dynamics of double-stranded DNA on a graphene oxide surface with both large unoxidized and oxidized regions

The adsorption dynamics of double-stranded DNA(dsDNA)molecules on a graphene oxide(GO)surface are important for applications of DNA/GO functional structures in biosensors,biomedicine and materials science.In this work,molecular dynamics simulations were used to examine the adsorption of different length dsDNA molecules(from 4 bp to24 bp)on the GO surface.The dsDNA molecules could be adsorbed on the GO surface through the terminal bases and stand on the GO surface.For short dsDNA(4 bp)molecules,the double-helix structure was partially or totally broken and the adsorption dynamics was affected by the structural fluctuation of short dsDNA and the distribution of the oxidized groups on the GO surface.For long dsDNA molecules(from 8 bp to 24 bp)adsorption is stable.By nonlinear fitting of the contact angle between the axis of the dsDNA molecule and the GO surface,we found that a dsDNA molecule adsorbed on a GO surface has the chance of orienting parallel to the GO surface if the length of the dsDNA molecule is longer than 54 bp.We attributed this behavior to the flexibility of dsDNA molecules.With increasing length,the flexibility of dsDNA molecules also increases,and this increasing flexibility gives an adsorbed dsDNA molecule more chance of reaching the GO surface with the free terminal.This work provides a whole picture of adsorption of dsDNA molecules on the GO surface and should be of benefit for the design of DNA/GO based biosensors.

Reflection and refraction of waves in oscillatory media

This paper uses the two-dimensional Brusselator model to study reflection and refraction of chemical waves. It presents some boundary conditions of chemical waves, with which occurence of observed phenomena at interface as refraction and reflection of chemical waves can be interpreted. Moreover, the angle of reflection may be calculated by using the boundary conditions. It finds that reflection and refraction of chemical waves can occur simultaneously even if plane wave goes from a medium with higher speed to a medium with lower speed, provided the incident angle is larger than the critical angle.

Combination of multi-focus Raman spectroscopy and compressive sensing for parallel monitoring of single-cell dynamics

To overcome the low efficiency of conventional confocal Raman spectroscopy,many efforts have been devoted to parallelizing the Raman excitation and acquisition,in which the scattering from multiple foci is projected onto different locations on a spectrometer's CCD,along either its vertical,horizontal dimension,or even both.While the latter projection scheme relieves the limitation on the row numbers of the CCD,the spectra of multiple foci are recorded in one spectral channel,resulting in spectral overlapping.Here,we developed a method under a com-pressive sensing framework to demultiplex the superimposed spectra of multiple cells during their dynamic processes.Unlike the previous methods which ignore the information connection be-tween the spectra of the cells recorded at different time,the proposed method utilizes a prior that a cell's spectra acquired at different time have the same sparsity structure in their principal components.Rather than independently demultiplexing the mixed spectra at the individual time intervals,the method demultiplexes the whole spectral sequence acquired continuously during the dynamic process.By penalizing the sparsity combined from all time intervals,the collaborative optimization of the inversion problem gave more accurate recovery results.The performances of the method were substantiated by a 1D Raman tweezers array,which monitored the germination of multiple bacterial spores.The method can be extended to the monitoring of many living cells randomly scattering on a coverslip,and has a potential to improve the throughput by a few orders.

Influence of atomic force microscope(AFM) probe shape on adhesion force measured in humidity environment

In micro-manipulation, the adhesion force has very important influence on behaviors of micro-objects. Here, a theoretical study on the effects of humidity on the adhesion force is presented between atomic force microscope （AFM） tips and substrate. The analysis shows that the precise tip geometry plays a critical role on humidity depen- dence of the adhesion force, which is the dominant factor in manipulating micro-objects in AFM experiments. For a blunt （paraboloid） tip, the adhesion force versus humidity curves tends to the apparent contrast （peak-to-valley corrugation） with a broad range. This paper demonstrates that the abrupt change of the adhesion force has high correla- tion with probe curvatures, which is mediated by coordinates of solid-liquid-vapor contact lines （triple point） on the probe profiles. The study provides insights for further under- standing nanoscale adhesion forces and the way to choose probe shapes in manipulating micro-objects in AFM experiments.

Light manipulation by dual channel storage in ultra-cold Rydberg medium

We investigate the light propagation dynamics in ultra-cold Rydberg medium with inverted-Y configuration based on the superatom theory.It is viable to store light information in two types of atomic spin coherence(trivial spin coherence and Rydberg spin coherence),which makes the system a prospective platform for versatile light manipulation.A normal feature is to realize efficient light storage with simultaneous resonant control fields applied.An intriguing feature is to split light into two beams with different intensities and statistical properties if the control fields are applied separately.The beam of light retrieved from the Rydberg spin coherence is severely attenuated and shows anti-bunching character accompanied by the cooperative optical nonlinearity.Moreover,generation and manipulation of beating signal are achievable by applying the non-resonant control fields.

Analysis of humidity-dependent adhesion between a probe tip and a surface

Adhesive forces commonly exhibit a monotonic increase or a maximum with increasing relative humidity. However, anomalous behavior has been reported. Here, a numerical model of adhesive forces, comprised mainly of capillary and van der Waals forces, between a tip and a surface is established. It is described by a power law that considers the geometry, the liquid bridge wetting radius, the contact angle, and the separation distance. Capillary forces （sum of surface tension and Laplace pressure） and van der Waals forces are calculated. The latter cannot be neglected in the adhesion even at high humidity. Decrease in adhesion with increasing relative humidity can be attributed to a blunt tip shape, which is validated by experimental data. Specifically, the decrease in adhesion is attributed primarily to a transition from a rounded to a blunt tip shape. Structuring objects at the micro- or nanoscale can either increase or decrease adhesion as a function of relative humidity. This has a wide range of applications in robotic manipulation and can provide a better understanding of adhesion mechanisms in atomic force microscopy in ambient air.

Wave Optics in Discrete Excitable Media

Refraction and reflection of planar waves in a discrete excitable medium is numerically investigated by using the Greenberg-Hasting model.It is fonnd that the medium is anisotropic because the speed of the planar wave depends on the excitability of the medium and the direction of wave propagation.The reflection,diffraction,refraction,double refraction and delayed refraction are observed by using the correct choice of model parameters.When the incident angle is larger than the critical angle,the reflection,which is a back refraction,takes place.The reflection angle changes with the incident angle.The refraction in certain situations obeys Shell's law.Also,our results demonstrate that the incident,refracted and reflected waves can have different periods.The reflected and refracted waves can disappear.

Ideal optomechanically induced transparency generation in a cavity optoelectromechanical system

The ideal optomechanically induced transparency effects of an output probe field are investigated in a cavity optoelectromechanical system,which is composed of an optical cavity,a charged mechanical resonator,and a charged object.Although the charged mechanical resonator damping rate is nonzero,the ideal optomechanically induced transparency can still appear due to the non-rotating wave approximation effect in the system.The location of optomechanically induced transparency dip can be controlled via the Coulomb coupling strength.In addition,we find that both the transparency window width and the maximum dispersion curve slope are closely related to the optical cavity decay rate.

High-Sensitivity Temperature Sensor Based on Polarization Maintaining Fiber Sagnac Loop

A high-sensitivity all-fiber temperature sensor based on a Sagnac interferometer is demonstrated by splicing a section of polarization maintaining fiber(PMF)between two sections of standard single mode fibers(SMFs).In this sensor,the SMF-PMF-SMF structure in the Sagnac loop is bent into a circle to enhance the sensitivity.The length and curvature of the PMF in the loop are investigated and can be optimized to further increase the temperature sensitivity of the sensor. Results show that the radius of the circle has an important effect upon temperature sensitivity due to the bend-induced birefringence variation of the PMF.The SMF-PMF-SMF structure bent into a circle with a radius of 30mm exhibits a high-sensitivity temperature of 1.73nm/℃.The sensor is provided with the advantages of easy fabrication,low-insertion loss,and high sensitivity,which may find potential applications in the field of high precision temperature measurement.

Perfect Optical Nonreciprocity with Mechanical Driving in a Three-Mode Optomechanical System

Nonreciprocal devices are indispensable for building quantum networks and ubiquitous in modern communication technology.Here, we study perfect optical nonreciprocity in a three-mode optomechanical system with mechanical driving.The scheme relies on the interference between optomechanical interaction and mechanical driving.We find perfect optical nonreciprocity can be achieved even though nonreciprocal phase difference is zero if we drive the system by a mechanical driving with a nonzero phase.We obtain the essential conditions for perfect optical nonreciprocity and analyze properties of the optical nonreciprocal transmission.These results can be used to control optical transmission in quantum information processing.