[Cp^(*)Co(CO)l_(2)]effectively catalyzes pyridyl-directed C-H allylation of arenes with allylic amines in the presence of AgOAc and CF_(3)COOAg.The reaction features ortho-position monoallylation of 2-pyridylarenes,gi...[Cp^(*)Co(CO)l_(2)]effectively catalyzes pyridyl-directed C-H allylation of arenes with allylic amines in the presence of AgOAc and CF_(3)COOAg.The reaction features ortho-position monoallylation of 2-pyridylarenes,giving the allylated arenes in moderate to high yields.A range of functional groups including OMe,Me,Ph,F,Cl,Br,CF_(3),C(0)Me,COOEt,and COOH groups are tolerated.Pyrim-idyl-directed C-H allylation of arenes were also performed under the same conditions.Reaction of 2-phenylpyrimidine,2-(4-methoxyphenyl)pyrimidine/and 2-(3-fluorophenyl)pyrimidine leads to a mixture of ortho-position mono-and bisallylation products.Reaction of other 2-(substituted aryl)pyrimidines resulted in ortho-position monoallylation products.展开更多
基金the National Natural Science Foundation of China(No.21372212)the National Basic Research Program of China(No.2015CB856600)is greatly acknowledged.
文摘[Cp^(*)Co(CO)l_(2)]effectively catalyzes pyridyl-directed C-H allylation of arenes with allylic amines in the presence of AgOAc and CF_(3)COOAg.The reaction features ortho-position monoallylation of 2-pyridylarenes,giving the allylated arenes in moderate to high yields.A range of functional groups including OMe,Me,Ph,F,Cl,Br,CF_(3),C(0)Me,COOEt,and COOH groups are tolerated.Pyrim-idyl-directed C-H allylation of arenes were also performed under the same conditions.Reaction of 2-phenylpyrimidine,2-(4-methoxyphenyl)pyrimidine/and 2-(3-fluorophenyl)pyrimidine leads to a mixture of ortho-position mono-and bisallylation products.Reaction of other 2-(substituted aryl)pyrimidines resulted in ortho-position monoallylation products.
