The current corona-2 pandemic has stimulated wide research for hydroxychloroquine(Quine)therapy and lately,prophylaxis.To optimize prophylaxis proper methods of use are explained.The focus is on tools of assessment an...The current corona-2 pandemic has stimulated wide research for hydroxychloroquine(Quine)therapy and lately,prophylaxis.To optimize prophylaxis proper methods of use are explained.The focus is on tools of assessment and robust comparison;defining infection objectively;loading and maintenance dose designing based on pharmaco-viro-kinetics;confirming Quine threshold-levels and its sufficiency;and Quine side-effects vigilance/amelioration.Attention to statistics to study valid endpoints of goals in appropriately-sized population is essential.Mass interactive quine dose auto designer software is built to simplify,optimize and help collaboration of complex Quine dosing system.A similar chloroquine software can be built.展开更多
文摘The current corona-2 pandemic has stimulated wide research for hydroxychloroquine(Quine)therapy and lately,prophylaxis.To optimize prophylaxis proper methods of use are explained.The focus is on tools of assessment and robust comparison;defining infection objectively;loading and maintenance dose designing based on pharmaco-viro-kinetics;confirming Quine threshold-levels and its sufficiency;and Quine side-effects vigilance/amelioration.Attention to statistics to study valid endpoints of goals in appropriately-sized population is essential.Mass interactive quine dose auto designer software is built to simplify,optimize and help collaboration of complex Quine dosing system.A similar chloroquine software can be built.
