Hot debates exist regarding whether patients who had an acute large vessel occlusion stroke(LVOS)can skip tissue plasminogen activator(tPA)and go directly to thrombectomy in comprehensive stroke centres.Three head-to-...Hot debates exist regarding whether patients who had an acute large vessel occlusion stroke(LVOS)can skip tissue plasminogen activator(tPA)and go directly to thrombectomy in comprehensive stroke centres.Three head-to-head randomised clinical trials(RCTs)of direct endovascular treatment(dEVT)versus bridge therapy(BT)with intravenous alteplase have been recently completed in the Asian population.The DIRECT-MT(Direct Intraarterial Thrombectomy in Order to Revascularize Acute Ischemic Stroke Patients with Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals:a Multicenter Randomized Clinical Trial)Study randomly enrolled 656 patients who had an acute ischaemic stroke with anterior circulation LVOS across 41 large teaching hospitals in China to receive BT or dEVT within 4.5 hours after symptom onset.展开更多
文摘Hot debates exist regarding whether patients who had an acute large vessel occlusion stroke(LVOS)can skip tissue plasminogen activator(tPA)and go directly to thrombectomy in comprehensive stroke centres.Three head-to-head randomised clinical trials(RCTs)of direct endovascular treatment(dEVT)versus bridge therapy(BT)with intravenous alteplase have been recently completed in the Asian population.The DIRECT-MT(Direct Intraarterial Thrombectomy in Order to Revascularize Acute Ischemic Stroke Patients with Large Vessel Occlusion Efficiently in Chinese Tertiary Hospitals:a Multicenter Randomized Clinical Trial)Study randomly enrolled 656 patients who had an acute ischaemic stroke with anterior circulation LVOS across 41 large teaching hospitals in China to receive BT or dEVT within 4.5 hours after symptom onset.
