Purpose: To evaluate Orbscan II (Bausch & Lomb,Orbtek Inc.,Salt Lake City,UT) corneal topography in individuals with myopia. Design: Retrospective,observational,consecutive,clinical case series. Participants: One ...Purpose: To evaluate Orbscan II (Bausch & Lomb,Orbtek Inc.,Salt Lake City,UT) corneal topography in individuals with myopia. Design: Retrospective,observational,consecutive,clinical case series. Participants: One hundred forty eyes of 70 persons with myopia. Methods: Manifest refraction results and the Orbscan II corneal topographic maps were reviewed retrospectively. Main Outcome Measures: Refractive powers and the following test indices produced by Orbscan II were analyzed: anterior elevation best-fit sphere (BFS),posterior elevation BFS,maximum posterior elevation (Max PE),radius of Max PE,maximum keratometry,minimum ker atometry,astigmatism,3-mm irregularity,3-mm mean power,3-mm astigmatism,5-mm irregularity,5-mm mean power,5-mm astigmatism,corneal diameter,pupil diameter,thinnest pachymetry,and anterior chamber depth. The correlations between right eyes and left eyes and between indices were explored. Results: Of the 140 eyes,the mean manifest refraction was-5.27± 2.19 diopters (D; range,-10.50 to 0.00 D),the mean Max PE was 28± 7 μ m,and the mean maximum keratometry was 44.5± 1.5 D. Correlation coefficient analyses of Orbscan II quantitative indices combined with pattern recognition showed that there were high degrees of correlations between the right and left eyes of each individual patient. Maximum posterior elevation,corneal irregularity,and thinnest pachymetry did not vary with the degree of maximum keratometry. Conclusions: This article provides a detailed description and analysis of Orbscan II corneal topography of a normal population with myopia. This helps in establishing normal standards in Orbscan II corneal topography that will aid in preoperative assessment in refractive surgery.展开更多
·AIM:To report a successful osteo-odonto keratoprosthesis(OOKP) procedure in a case of end stage of corneal blindness due to Stevens-Johnson syndrome (SJS).·METHODS:An interventional case report.·RESULT...·AIM:To report a successful osteo-odonto keratoprosthesis(OOKP) procedure in a case of end stage of corneal blindness due to Stevens-Johnson syndrome (SJS).·METHODS:An interventional case report.·RESULTS:We describe a 35-year-old Indian woman,a known case of SJS with bilateral dry eyes and corneal blindness (failed corneal graft with vascularised total corneal opacity in the right eye and non-healing corneal ulcer in the left eye).Vision was hand movement only in both eyes.The corneal ulcer healed with medical treatment resulting in vascularised total corneal opacity with no improvement in vision.OOKP was performed in the right eye and the vision was improved from hand movement to 6/6.The same vision was maintained in the right eye at the last follow-up 5 years after surgery.·CONCLUSION:OOKP provides good visual rehabilitation with long-term anatomically stable prosthesis in patients with end-stage of ocular surface disorders and corneal blindness secondary to SJS.·展开更多
Dear Editor,We present a case of a healthy 32-year-old man who developed bilateral corneal ulceration 3 wk after commencing dupilumab for atopic dermatitis. Dupilumab is a recently introduced systemic monoclonal antib...Dear Editor,We present a case of a healthy 32-year-old man who developed bilateral corneal ulceration 3 wk after commencing dupilumab for atopic dermatitis. Dupilumab is a recently introduced systemic monoclonal antibody used in the treatment of moderate-to-severe atopic dermatitis, showing efficacy in clinical trials;. Several publications have reported ocular surface complications associated with dupilumab.展开更多
文摘Purpose: To evaluate Orbscan II (Bausch & Lomb,Orbtek Inc.,Salt Lake City,UT) corneal topography in individuals with myopia. Design: Retrospective,observational,consecutive,clinical case series. Participants: One hundred forty eyes of 70 persons with myopia. Methods: Manifest refraction results and the Orbscan II corneal topographic maps were reviewed retrospectively. Main Outcome Measures: Refractive powers and the following test indices produced by Orbscan II were analyzed: anterior elevation best-fit sphere (BFS),posterior elevation BFS,maximum posterior elevation (Max PE),radius of Max PE,maximum keratometry,minimum ker atometry,astigmatism,3-mm irregularity,3-mm mean power,3-mm astigmatism,5-mm irregularity,5-mm mean power,5-mm astigmatism,corneal diameter,pupil diameter,thinnest pachymetry,and anterior chamber depth. The correlations between right eyes and left eyes and between indices were explored. Results: Of the 140 eyes,the mean manifest refraction was-5.27± 2.19 diopters (D; range,-10.50 to 0.00 D),the mean Max PE was 28± 7 μ m,and the mean maximum keratometry was 44.5± 1.5 D. Correlation coefficient analyses of Orbscan II quantitative indices combined with pattern recognition showed that there were high degrees of correlations between the right and left eyes of each individual patient. Maximum posterior elevation,corneal irregularity,and thinnest pachymetry did not vary with the degree of maximum keratometry. Conclusions: This article provides a detailed description and analysis of Orbscan II corneal topography of a normal population with myopia. This helps in establishing normal standards in Orbscan II corneal topography that will aid in preoperative assessment in refractive surgery.
文摘·AIM:To report a successful osteo-odonto keratoprosthesis(OOKP) procedure in a case of end stage of corneal blindness due to Stevens-Johnson syndrome (SJS).·METHODS:An interventional case report.·RESULTS:We describe a 35-year-old Indian woman,a known case of SJS with bilateral dry eyes and corneal blindness (failed corneal graft with vascularised total corneal opacity in the right eye and non-healing corneal ulcer in the left eye).Vision was hand movement only in both eyes.The corneal ulcer healed with medical treatment resulting in vascularised total corneal opacity with no improvement in vision.OOKP was performed in the right eye and the vision was improved from hand movement to 6/6.The same vision was maintained in the right eye at the last follow-up 5 years after surgery.·CONCLUSION:OOKP provides good visual rehabilitation with long-term anatomically stable prosthesis in patients with end-stage of ocular surface disorders and corneal blindness secondary to SJS.·
文摘Dear Editor,We present a case of a healthy 32-year-old man who developed bilateral corneal ulceration 3 wk after commencing dupilumab for atopic dermatitis. Dupilumab is a recently introduced systemic monoclonal antibody used in the treatment of moderate-to-severe atopic dermatitis, showing efficacy in clinical trials;. Several publications have reported ocular surface complications associated with dupilumab.
