In the era of rapid development of Internet of Things(IoT),numerous machine-to-machine technologies have been applied to the industrial domain.Due to the divergence of IoT solutions,the industry is faced with a need t...In the era of rapid development of Internet of Things(IoT),numerous machine-to-machine technologies have been applied to the industrial domain.Due to the divergence of IoT solutions,the industry is faced with a need to apply various technologies for automation and control.This fact leads to a demand for an establishing interworking mechanism which would allow smooth interoperability between heterogeneous devices.One of the major protocols widely used today in industrial electronic devices is Modbus.However,data generated by Modbus devices cannot be understood by IoT applications using different protocols,so it should be applied in a couple with an IoT service layer platform.oneM2M,a global IoT standard,can play the role of interconnecting various protocols,as it provides flexible tools suitable for building an interworking framework for industrial services.Therefore,in this paper,we propose an interworking architecture between devices working on the Modbus protocol and an IoT platform implemented based on oneM2M standards.In the proposed architecture,we introduce the way to model Modbus data as oneM2M resources,rules to map them to each other,procedures required to establish interoperable communication,and optimization methods for this architecture.We analyze our solution and provide an evaluation by implementing it based on a solar power management use case.The results demonstrate that our model is feasible and can be applied to real case scenarios.展开更多
With the systematization of cyber threats, the variety of intrusion tools and intrusion methods has greatly reduced the cost of attackers’ threats to network security. Due to a large number of colleges and universiti...With the systematization of cyber threats, the variety of intrusion tools and intrusion methods has greatly reduced the cost of attackers’ threats to network security. Due to a large number of colleges and universities, teachers and students are highly educated and the Internet access rate is nearly 100%. The social status makes the university network become the main target of threat. The traditional defense method cannot cope with the current complex network attacks. In order to solve this problem, the threat intelligence sharing platform based on various threat intelligence sharing standards is established, which STIX and TAXII It is a widely used sharing standard in various sharing platforms. This paper analyzes the existing standards of STIX and TAXII, improves the STIX and TAXII standards based on the analysis results, and proposes a new type of STIX and TAXII based on the improved results. The standard design scheme of threat intelligence sharing platform suitable for college network environment features. The experimental results show that the threat intelligence sharing platform designed in this paper can be effectively applied to the network environment of colleges and universities.展开更多
Research on the population in western world showed that,MSE(muscle-strengthening exercise)is beneficial to the treatment of mental disorders.However,the situation in Chinese adults is little known.For this reason,the ...Research on the population in western world showed that,MSE(muscle-strengthening exercise)is beneficial to the treatment of mental disorders.However,the situation in Chinese adults is little known.For this reason,the study is performed to understand the connection between depression and MSE among college and university students in China aged between 18 to 24.1793 college students have been recruited,and their average age is 20.67.A questionnaire has been developed and it is self-reported and designed to collect information about MSE and participants,including body mass index and sex and so on.Sleep and physical activity have been evaluated by introducing two scales,that is,Pittsburgh Sleep Quality Index and International Physical Activity Questionnaire-Short Form,respectively.Moreover,Patient Health Questionnaire-9 has been adopted to indicate the severity of depression of participants.The link between depression and MSE has been studied by introducing multilevel linear regression.Among all these study participants,just 24.87%of them met the MSE standards of World Health Organization,that is,more than 2 days every week.The average depression score was 6.80(±5.19).Greater num-ber of days for MSE shows negative association with the depression,with (beta=-0.17,95%CI:-0.31 to-0.03,p=0.015).Those students failing to meet MSE standards are more susceptible to the depression risk(beta=0.63,95%CI:0.09–0.19,p=0.027).The results show that,there is a relationship between MSE participation and relieved status of depression among young adults in China.Interventions designed to relieve depression can be developed on the basis of MSE.展开更多
Though the lithium-ion battery is universally applied,the reliability of lithium-ion batteries remains a challenge due to various physicochemical reactions,electrode material degradation,and even thermal runaway.Accur...Though the lithium-ion battery is universally applied,the reliability of lithium-ion batteries remains a challenge due to various physicochemical reactions,electrode material degradation,and even thermal runaway.Accurate estimation and prediction of battery health conditions are crucial for battery safety management.In this paper,an end-cloud collaboration method is proposed to approach the track of battery degradation process,integrating end-side empirical model with cloud-side data-driven model.Based on ensemble learning methods,the data-driven model is constructed by three base models to obtain cloud-side highly accurate results.The double exponential decay model is utilized as an empirical model to output highly real-time prediction results.With Kalman filter,the prediction results of end-side empirical model can be periodically updated by highly accurate results of cloud-side data-driven model to obtain highly accurate and real-time results.Subsequently,the whole framework can give an accurate prediction and tracking of battery degradation,with the mean absolute error maintained below 2%.And the execution time on the end side can reach 261μs.The proposed end-cloud collaboration method has the potential to approach highly accurate and highly real-time estimation for battery health conditions during battery full life cycle in architecture of cyber hierarchy and interactional network.展开更多
Due to the inherent insecure nature of the Internet,it is crucial to ensure the secure transmission of image data over this network.Additionally,given the limitations of computers,it becomes evenmore important to empl...Due to the inherent insecure nature of the Internet,it is crucial to ensure the secure transmission of image data over this network.Additionally,given the limitations of computers,it becomes evenmore important to employ efficient and fast image encryption techniques.While 1D chaotic maps offer a practical approach to real-time image encryption,their limited flexibility and increased vulnerability restrict their practical application.In this research,we have utilized a 3DHindmarsh-Rosemodel to construct a secure cryptosystem.The randomness of the chaotic map is assessed through standard analysis.The proposed system enhances security by incorporating an increased number of system parameters and a wide range of chaotic parameters,as well as ensuring a uniformdistribution of chaotic signals across the entire value space.Additionally,a fast image encryption technique utilizing the new chaotic system is proposed.The novelty of the approach is confirmed through time complexity analysis.To further strengthen the resistance against cryptanalysis attacks and differential attacks,the SHA-256 algorithm is employed for secure key generation.Experimental results through a number of parameters demonstrate the strong cryptographic performance of the proposed image encryption approach,highlighting its exceptional suitability for secure communication.Moreover,the security of the proposed scheme has been compared with stateof-the-art image encryption schemes,and all comparison metrics indicate the superior performance of the proposed scheme.展开更多
Purpose:The aim of this study was to review,systematically,evidence concerning the link between the ACTN3 R577X polymorphism and the rates and severity of non-contact injuries and exercise-induced muscle damage in ath...Purpose:The aim of this study was to review,systematically,evidence concerning the link between the ACTN3 R577X polymorphism and the rates and severity of non-contact injuries and exercise-induced muscle damage in athletes and individuals enrolled in exercise training programs.Methods:A computerized literature search was performed in the electronic databases PubMed,Web of Science,and SPORTDiscus,from inception until November 2020.All included studies compared the epidemiological characteristics of non-contact injury between the different genotypes of the ACTN3 R577X polymorphism.Results:Our search identified 492 records.After the screening of titles,abstracts,and full texts,13 studies examining the association between the ACTN3 genotypes and the rate and severity of non-contact injury were included in the analysis.These studies were performed in 6 different countries(Spain,Japan,Brazil,China,the Republic of Korea,and Italy)and involved a total participant pool of 1093 participants.Of the studies,2 studies involved only women,5 studies involved only men,and 6 studies involved both men and women.All the studies included were classified as highquality studies(≥6 points in the Physiotherapy Evidence Database(PEDro)scale score).Overall,evidence suggests there is an association between the ACTN3 R577X genotype and non-contact injury in 12 investigations.Six studies observed a significant association between A CTN3 R577X polymorphism and exercise induced muscle damage:2 with non-contact ankle injury,3 with non-contact muscle injury,and 1 with overall non-contact injury.Conclusion:The present findings support the premise that possessing the ACTN3 XX genotype may predispose athletes to a higher probability of some non-contact injuries,such as muscle injury,ankle sprains,and higher levels of exercise-induced muscle damage.展开更多
Background: Compared to the general population, people who are at a high risk of or experience severe mental illness (SMI) such as psychosis, are more likely to have low levels of physical activity, high levels of sed...Background: Compared to the general population, people who are at a high risk of or experience severe mental illness (SMI) such as psychosis, are more likely to have low levels of physical activity, high levels of sedentary behaviour, and sleep problems. Intervention: The Well-Track intervention comprises a wearable activity and sleep tracker (Fitbit);one session with mental health service staff providing physical activity and sleep hygiene advice;a brief motivational interview;completing a goal setting workbook;and one or two further engagement, feedback and discussion sessions. Participants: Twenty-four participants using an early intervention in psychosis (EIP) or at-risk mental state (ARMS) service completed an eight-week, three session intervention (14 males and 10 females), with an age range of 18 - 61, and average age of 27.75 years. Methods: An open-label patient cohort design with no control group. Pre-intervention, 4-week and 8-week intervention assessments using participant self-report measures: Patient Health Questionnaire (PHQ-9) (depression), Warwick–Edinburgh Mental Wellbeing Scale (WEMWBS), and Sleep Conditioning Index (SCI);and clinician measurement of body weight. Results: Mean scores showed a significant improvement in PHQ-9 from 9.29 (SD 5.89) to 5.58 (SD 3.68) at 4 weeks and to 5.83 (SD 4.40) at 8 weeks, with large effect sizes. For those who met a diagnosis of depression at baseline, at 4 week follow-up seven participants (26%) experienced remission and nine (33%) reliable improvement, and at 8 week follow-up four (21%) experienced remission and seven (37%) reliable improvement. WEMWBS scores significantly improved, from 44.04 (SD 9.44) to 48.54 (SD 8.71) at 4 weeks and to 48.67 (SD 8.76) at 8 weeks, with large effect sizes. Body weight did not change significantly, remaining unchanged at 4 weeks and reduced from a mean of 82.8 kg (baseline) to 80.15 kg at 8 weeks, a reduction of 2.65 kg. Conclusion: Well-Track was integrated into an EIP and ARMS service and was found to be beneficial in terms of wellbeing, depression, sleep, and preventing weight gain (either as a two or three engagement point intervention). Well-Track could be delivered through EIP and ARMS services to promote healthy lifestyle behaviours.展开更多
Within high-risk industries, efficient management of safety is an important element of organisational efforts to reduce accidents. Most organisations such as nuclear, aviation and oil and gas sectors have a safety man...Within high-risk industries, efficient management of safety is an important element of organisational efforts to reduce accidents. Most organisations such as nuclear, aviation and oil and gas sectors have a safety management system (SMS) which provides sequence of organisational procedure to identify hazards, mitigation of risk, measure performance, investigate incidents and maintain an on-going continuous improvement. However, experts believe that when such complex organisations complement safety management system with isomorphic lessons and organisational learning strategies to manage safety, there will be a high propensity to aggressively reduce risk and save cost. Undoubtedly, learning from accidents/incidents is one of many ways to manage safely in any given organisation. As a result, this paper is intended to ascertain if organisations use isomorphic lessons and organisational learning as strong feature of organisation’s practice capable of promoting stronger safety culture;and if lessons learned from other high-risk sectors can help inform risk-based decisions in organisations. Risk experts and by extension the nuclear sector, could have learned from past accident such as the Three Mile Island of 1979 and employ lessons learned to forestall future occurrences. Primary data was gathered via online, and research population are health and safety professionals from aviation, nuclear, and the oil and gas sectors. The sample size recruited are aviation (n = 59, 25%);nuclear (n = 124, 54%);and oil and gas (n = 49, 21%). Statistical Package for the Social Sciences (SPSS) software was used to analyse 232 responses used for this paper.展开更多
BACKGROUNDPeriod poverty is a global health and social issue that needs to be addressed.It has been reported that many females compromise their education,employment,and social commitments during their menstruation day...BACKGROUNDPeriod poverty is a global health and social issue that needs to be addressed.It has been reported that many females compromise their education,employment,and social commitments during their menstruation days due to a number of reasons,including lack of access to toilets or menstrual products.AIM To provide a comprehensive understanding on period poverty,including outcomes associated with menstruation.METHODS All observational and randomised clinical trials reporting menstruation challenges,menstrual poverty and menstrual products were included.Our search strategy included multiple electronic databases of PubMed,Web of Science,ScienceDirect,ProQuest and EMBASE.Studies published in a peer review journal in English between the 30th of April 1980 and the 30th of April 2022 were included.The Newcastle-Ottawa Scale was used to assess the risk of bias of the systematic included studies.Pooled odds ratios(ORs)together with 95%confidence intervals(CIs)are reported overall and for sub-groups.RESULTS A total of 80 studies were systematically selected,where 38 were included in the meta-analysis.Of the 38 studies,28 focused on children and young girls(i.e.,10-24 years old)and 10 included participants with a wider age range of 15-49 years.The prevalence of using disposable sanitary pads was 45%(95%CI:0.35-0.58).The prevalence of menstrual education pre-menarche was 68%(95%CI:0.56-0.82).The prevalence of good menstrual hygiene management(MHM)was 39%(95%CI:0.25-0.61).Women in rural areas(OR=0.30,95%CI:0.13-0.69)were 0.70 times less likely to have good MHM practices than those living in urban areas.CONCLUSION There was a lack of evidence,especially from low-and middle-income countries.Further research to better understand the scope and prevalence of period poverty should be considered.This will enable the development of improved policies to increase access to menstrual products and medical support where necessary.展开更多
Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts normal liver functionality. It is a pathological stage in several untreated chronic liver diseases such as the iron overl...Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts normal liver functionality. It is a pathological stage in several untreated chronic liver diseases such as the iron overload syndrome hereditary haemochromatosis, viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis and diabetes. Interestingly, regardless of the aetiology, iron-loading is frequently observed in chronic liver diseases. Excess iron can feed the Fenton reaction to generate unquenchable amounts of free radicals that cause grave cellular and tissue damage and thereby contribute to fibrosis. Moreover, excess iron can induce fibrosis-promoting signals in the parenchymal and non-parenchymal cells, which accelerate disease progression and exacerbate liver pathology. Fibrosis regression is achievable following treatment, but if untreated or unsuccessful, it can progress to the irreversible cirrhotic stage leading to organ failure and hepatocellular carcinoma, where resection or transplantation remain the only curative options. Therefore,understanding the role of iron in liver fibrosis is extremely essential as it can help in formulating iron-related diagnostic, prognostic and treatment strategies. These can be implemented in isolation or in combination with the current approaches to prepone detection, and halt or decelerate fibrosis progression before it reaches the irreparable stage. Thus, this review narrates the role of iron in liver fibrosis. It examines the underlying mechanisms by which excess iron can facilitate fibrotic responses. It describes the role of iron in various clinical pathologies and lastly,highlights the significance and potential of iron-related proteins in the diagnosis and therapeutics of liver fibrosis.展开更多
To achieve zero-defect production during computer numerical control(CNC)machining processes,it is imperative to develop effective diagnosis systems to detect anomalies efficiently.However,due to the dynamic conditions...To achieve zero-defect production during computer numerical control(CNC)machining processes,it is imperative to develop effective diagnosis systems to detect anomalies efficiently.However,due to the dynamic conditions of the machine and tooling during machining processes,the relevant diagnosis systems currently adopted in industries are incompetent.To address this issue,this paper presents a novel data-driven diagnosis system for anomalies.In this system,power data for condition monitoring are continuously collected during dynamic machining processes to support online diagnosis analysis.To facilitate the analysis,preprocessing mechanisms have been designed to de-noise,normalize,and align the monitored data.Important features are extracted from the monitored data and thresholds are defined to identify anomalies.Considering the dynamic conditions of the machine and tooling during machining processes,the thresholds used to identify anomalies can vary.Based on historical data,the values of thresholds are optimized using a fruit fly optimization(FFO)algorithm to achieve more accurate detection.Practical case studies were used to validate the system,thereby demonstrating the potential and effectiveness of the system for industrial applications.展开更多
Increased urbanisation,economic growth,and long-term climate variability have made both the UK and China more susceptible to urban and river flooding,putting people and property at increased risk.This paper presents a...Increased urbanisation,economic growth,and long-term climate variability have made both the UK and China more susceptible to urban and river flooding,putting people and property at increased risk.This paper presents a review of the current flooding challenges that are affecting the UK and China and the actions that each country is undertaking to tackle these problems.Particular emphases in this paper are laid on(1)learning from previous flooding events in the UK and China,and(2)which management methodologies are commonly used to reduce flood risk.The paper concludes with a strategic research plan suggested by the authors,together with proposed ways to overcome identified knowledge gaps in flood management.Recommendations briefly comprise the engagement of all stakeholders to ensure a proactive approach to land use planning,early warning systems,and water-sensitive urban design or redesign through more effective policy,multi-level flood models,and data driven models of water quantity and quality.展开更多
In the present paper, the isogeometric analysis(IGA) of free-form planar curved beams is formulated based on the nonlinear Timoshenko beam theory to investigate the large deformation of beams with variable curvature...In the present paper, the isogeometric analysis(IGA) of free-form planar curved beams is formulated based on the nonlinear Timoshenko beam theory to investigate the large deformation of beams with variable curvature. Based on the isoparametric concept, the shape functions of the field variables(displacement and rotation) in a finite element analysis are considered to be the same as the non-uniform rational basis spline(NURBS) basis functions defining the geometry. The validity of the presented formulation is tested in five case studies covering a wide range of engineering curved structures including from straight and constant curvature to variable curvature beams. The nonlinear deformation results obtained by the presented method are compared to well-established benchmark examples and also compared to the results of linear and nonlinear finite element analyses. As the nonlinear load-deflection behavior of Timoshenko beams is the main topic of this article, the results strongly show the applicability of the IGA method to the large deformation analysis of free-form curved beams. Finally, it is interesting to notice that, until very recently, the large deformations analysis of free-form Timoshenko curved beams has not been considered in IGA by researchers.展开更多
The major drawback associated with PEEK implants is their biologically inert surface,which caused unsatisfactory cellular response and poor adhesion between the implants and surrounding soft tissues against proper bon...The major drawback associated with PEEK implants is their biologically inert surface,which caused unsatisfactory cellular response and poor adhesion between the implants and surrounding soft tissues against proper bone growth.In this study,polyetheretherketone(PEEK)was incorporated with calcium hydroxyapatite(cHAp)to fabricate a PEEK-cHAp biocomposite,using the fused deposition modeling(FDM)method and a surface treatment strategy to create microporous architectures onto the filaments of PEEK lattice scaffold.Also,nanostructure and morphological tests of the PEEK-cHAp biocomposite were modeled and analyzed on the FDM-printed PEEK-cHAp biocomposite sample to evaluate its mechanical and thermal strengths as well as in vitro cytotoxicity via a scanning electron microscope(SEM).A technique was used innovatively to create and investigate the porous nanostructure of the PEEK with controlled pore size and distribution to promote cell penetration and biological integration of the PEEK-cHAp into the tissue.In vivo tests demonstrated that the surface-treated micropores facilitated the adhesion of newly regenerated soft tissues to form tight implant-tissue interfacial bonding between the cHAp and PEEK.The results of the cell culture depicted that PEEK-cHAp exhibited better cell proliferation attachment spreading and higher alkaline phosphatase activity than PEEK alone.Apatite islands formed on the PEEK-cHAp composite after immersion in simulated body fluid of Dulbecco’s modified Eagle medium(DMEM)for 14 days and grew continuously with more or extended periods.The microstructure treatment of the crystallinity of PEEK was comparatively and significantly different from the PEEK-cHAp sample,indicating a better treatment of PEEK-cHAp.The in vitro results obtained from the PEEK-cHAp biocomposite material showed its biodegradability and performance suitability for bone implants.This study has potential applications in the field of biomedical engineering to strengthen the conceptual knowledge of FDM and medical implants fabricated from PEEK-cHAp biocomposite materials.展开更多
The mechanical performances and water retention characteristics of clays,stabilised by partial substitution of cement with by-products and inclusion of a nanotechnology-based additive called RoadCem(RC),are studied in...The mechanical performances and water retention characteristics of clays,stabilised by partial substitution of cement with by-products and inclusion of a nanotechnology-based additive called RoadCem(RC),are studied in this research.The unconfined compression tests and one-dimensional oedometer swelling were performed after 7 d of curing to understand the influence of addition of 1%of RC material in the stabilised soils with the cement partially replaced by 49%,59%and 69%of ground granulated blast furnace slag(GBBS)or pulverised fuel ash(PFA).The moisture retention capacity of the stabilised clays was also explored using the soil-water retention curve(SWRC)from the measured suctions.Results confirmed an obvious effect of the use of RC with the obtained strength and swell properties of the stabilised clays suitable for road application at 50%replacement of cement.This outcome is associated with the in-depth and penetrating hydration of the cementitious materials by the RC and water which results in the production of needle-like matrix with interlocking filaments e a phenomenon referred to as the‘wrapping’effect.On the other hand,the SWRC used to describe the water holding capacity and corresponding swell mechanism of clays stabilised by a proportion of RC showed a satisfactory response.The moisture retention of the RC-modified clays was initially higher but reduced subsequently as the saturation level increased with decreasing suction.This phenomenon confirmed that clays stabilised by including the RC are water-proof in nature,thus ensuring reduced porosity and suction even at reduced water content.Overall,the stabilised clays with the combination of cement,GGBS and RC showed a better performance compared to those with the PFA included.展开更多
基金the support of the Korea Research Foundation with the funding of the Ministry of Science and Information and Communication Technology(No.2018-0-88457,development of translucent solar cells and Internet of Things technology for Solar Signage).
文摘In the era of rapid development of Internet of Things(IoT),numerous machine-to-machine technologies have been applied to the industrial domain.Due to the divergence of IoT solutions,the industry is faced with a need to apply various technologies for automation and control.This fact leads to a demand for an establishing interworking mechanism which would allow smooth interoperability between heterogeneous devices.One of the major protocols widely used today in industrial electronic devices is Modbus.However,data generated by Modbus devices cannot be understood by IoT applications using different protocols,so it should be applied in a couple with an IoT service layer platform.oneM2M,a global IoT standard,can play the role of interconnecting various protocols,as it provides flexible tools suitable for building an interworking framework for industrial services.Therefore,in this paper,we propose an interworking architecture between devices working on the Modbus protocol and an IoT platform implemented based on oneM2M standards.In the proposed architecture,we introduce the way to model Modbus data as oneM2M resources,rules to map them to each other,procedures required to establish interoperable communication,and optimization methods for this architecture.We analyze our solution and provide an evaluation by implementing it based on a solar power management use case.The results demonstrate that our model is feasible and can be applied to real case scenarios.
文摘With the systematization of cyber threats, the variety of intrusion tools and intrusion methods has greatly reduced the cost of attackers’ threats to network security. Due to a large number of colleges and universities, teachers and students are highly educated and the Internet access rate is nearly 100%. The social status makes the university network become the main target of threat. The traditional defense method cannot cope with the current complex network attacks. In order to solve this problem, the threat intelligence sharing platform based on various threat intelligence sharing standards is established, which STIX and TAXII It is a widely used sharing standard in various sharing platforms. This paper analyzes the existing standards of STIX and TAXII, improves the STIX and TAXII standards based on the analysis results, and proposes a new type of STIX and TAXII based on the improved results. The standard design scheme of threat intelligence sharing platform suitable for college network environment features. The experimental results show that the threat intelligence sharing platform designed in this paper can be effectively applied to the network environment of colleges and universities.
基金funded by 2016 Hunan Province Social Science Key Project(Grant No.16ZDB015)2017 National Social Science Foundation of China(Grant No.21BTY032)+1 种基金2020 Hainan Province Tertiary School Research Project(Grant No.HNKY2020-53)2021 Hainan Province Philosophy and Social Development Project(Grant No.HNSK[ZC]21-173).
文摘Research on the population in western world showed that,MSE(muscle-strengthening exercise)is beneficial to the treatment of mental disorders.However,the situation in Chinese adults is little known.For this reason,the study is performed to understand the connection between depression and MSE among college and university students in China aged between 18 to 24.1793 college students have been recruited,and their average age is 20.67.A questionnaire has been developed and it is self-reported and designed to collect information about MSE and participants,including body mass index and sex and so on.Sleep and physical activity have been evaluated by introducing two scales,that is,Pittsburgh Sleep Quality Index and International Physical Activity Questionnaire-Short Form,respectively.Moreover,Patient Health Questionnaire-9 has been adopted to indicate the severity of depression of participants.The link between depression and MSE has been studied by introducing multilevel linear regression.Among all these study participants,just 24.87%of them met the MSE standards of World Health Organization,that is,more than 2 days every week.The average depression score was 6.80(±5.19).Greater num-ber of days for MSE shows negative association with the depression,with (beta=-0.17,95%CI:-0.31 to-0.03,p=0.015).Those students failing to meet MSE standards are more susceptible to the depression risk(beta=0.63,95%CI:0.09–0.19,p=0.027).The results show that,there is a relationship between MSE participation and relieved status of depression among young adults in China.Interventions designed to relieve depression can be developed on the basis of MSE.
基金financially supported by the National Natural Science Foundation of China(No.52102470)。
文摘Though the lithium-ion battery is universally applied,the reliability of lithium-ion batteries remains a challenge due to various physicochemical reactions,electrode material degradation,and even thermal runaway.Accurate estimation and prediction of battery health conditions are crucial for battery safety management.In this paper,an end-cloud collaboration method is proposed to approach the track of battery degradation process,integrating end-side empirical model with cloud-side data-driven model.Based on ensemble learning methods,the data-driven model is constructed by three base models to obtain cloud-side highly accurate results.The double exponential decay model is utilized as an empirical model to output highly real-time prediction results.With Kalman filter,the prediction results of end-side empirical model can be periodically updated by highly accurate results of cloud-side data-driven model to obtain highly accurate and real-time results.Subsequently,the whole framework can give an accurate prediction and tracking of battery degradation,with the mean absolute error maintained below 2%.And the execution time on the end side can reach 261μs.The proposed end-cloud collaboration method has the potential to approach highly accurate and highly real-time estimation for battery health conditions during battery full life cycle in architecture of cyber hierarchy and interactional network.
基金the Deanship of Scientific Research at Najran University for funding this work under the Research Groups Funding Program Grant Code(NU/RG/SERC/12/3).
文摘Due to the inherent insecure nature of the Internet,it is crucial to ensure the secure transmission of image data over this network.Additionally,given the limitations of computers,it becomes evenmore important to employ efficient and fast image encryption techniques.While 1D chaotic maps offer a practical approach to real-time image encryption,their limited flexibility and increased vulnerability restrict their practical application.In this research,we have utilized a 3DHindmarsh-Rosemodel to construct a secure cryptosystem.The randomness of the chaotic map is assessed through standard analysis.The proposed system enhances security by incorporating an increased number of system parameters and a wide range of chaotic parameters,as well as ensuring a uniformdistribution of chaotic signals across the entire value space.Additionally,a fast image encryption technique utilizing the new chaotic system is proposed.The novelty of the approach is confirmed through time complexity analysis.To further strengthen the resistance against cryptanalysis attacks and differential attacks,the SHA-256 algorithm is employed for secure key generation.Experimental results through a number of parameters demonstrate the strong cryptographic performance of the proposed image encryption approach,highlighting its exceptional suitability for secure communication.Moreover,the security of the proposed scheme has been compared with stateof-the-art image encryption schemes,and all comparison metrics indicate the superior performance of the proposed scheme.
文摘Purpose:The aim of this study was to review,systematically,evidence concerning the link between the ACTN3 R577X polymorphism and the rates and severity of non-contact injuries and exercise-induced muscle damage in athletes and individuals enrolled in exercise training programs.Methods:A computerized literature search was performed in the electronic databases PubMed,Web of Science,and SPORTDiscus,from inception until November 2020.All included studies compared the epidemiological characteristics of non-contact injury between the different genotypes of the ACTN3 R577X polymorphism.Results:Our search identified 492 records.After the screening of titles,abstracts,and full texts,13 studies examining the association between the ACTN3 genotypes and the rate and severity of non-contact injury were included in the analysis.These studies were performed in 6 different countries(Spain,Japan,Brazil,China,the Republic of Korea,and Italy)and involved a total participant pool of 1093 participants.Of the studies,2 studies involved only women,5 studies involved only men,and 6 studies involved both men and women.All the studies included were classified as highquality studies(≥6 points in the Physiotherapy Evidence Database(PEDro)scale score).Overall,evidence suggests there is an association between the ACTN3 R577X genotype and non-contact injury in 12 investigations.Six studies observed a significant association between A CTN3 R577X polymorphism and exercise induced muscle damage:2 with non-contact ankle injury,3 with non-contact muscle injury,and 1 with overall non-contact injury.Conclusion:The present findings support the premise that possessing the ACTN3 XX genotype may predispose athletes to a higher probability of some non-contact injuries,such as muscle injury,ankle sprains,and higher levels of exercise-induced muscle damage.
文摘Background: Compared to the general population, people who are at a high risk of or experience severe mental illness (SMI) such as psychosis, are more likely to have low levels of physical activity, high levels of sedentary behaviour, and sleep problems. Intervention: The Well-Track intervention comprises a wearable activity and sleep tracker (Fitbit);one session with mental health service staff providing physical activity and sleep hygiene advice;a brief motivational interview;completing a goal setting workbook;and one or two further engagement, feedback and discussion sessions. Participants: Twenty-four participants using an early intervention in psychosis (EIP) or at-risk mental state (ARMS) service completed an eight-week, three session intervention (14 males and 10 females), with an age range of 18 - 61, and average age of 27.75 years. Methods: An open-label patient cohort design with no control group. Pre-intervention, 4-week and 8-week intervention assessments using participant self-report measures: Patient Health Questionnaire (PHQ-9) (depression), Warwick–Edinburgh Mental Wellbeing Scale (WEMWBS), and Sleep Conditioning Index (SCI);and clinician measurement of body weight. Results: Mean scores showed a significant improvement in PHQ-9 from 9.29 (SD 5.89) to 5.58 (SD 3.68) at 4 weeks and to 5.83 (SD 4.40) at 8 weeks, with large effect sizes. For those who met a diagnosis of depression at baseline, at 4 week follow-up seven participants (26%) experienced remission and nine (33%) reliable improvement, and at 8 week follow-up four (21%) experienced remission and seven (37%) reliable improvement. WEMWBS scores significantly improved, from 44.04 (SD 9.44) to 48.54 (SD 8.71) at 4 weeks and to 48.67 (SD 8.76) at 8 weeks, with large effect sizes. Body weight did not change significantly, remaining unchanged at 4 weeks and reduced from a mean of 82.8 kg (baseline) to 80.15 kg at 8 weeks, a reduction of 2.65 kg. Conclusion: Well-Track was integrated into an EIP and ARMS service and was found to be beneficial in terms of wellbeing, depression, sleep, and preventing weight gain (either as a two or three engagement point intervention). Well-Track could be delivered through EIP and ARMS services to promote healthy lifestyle behaviours.
文摘Within high-risk industries, efficient management of safety is an important element of organisational efforts to reduce accidents. Most organisations such as nuclear, aviation and oil and gas sectors have a safety management system (SMS) which provides sequence of organisational procedure to identify hazards, mitigation of risk, measure performance, investigate incidents and maintain an on-going continuous improvement. However, experts believe that when such complex organisations complement safety management system with isomorphic lessons and organisational learning strategies to manage safety, there will be a high propensity to aggressively reduce risk and save cost. Undoubtedly, learning from accidents/incidents is one of many ways to manage safely in any given organisation. As a result, this paper is intended to ascertain if organisations use isomorphic lessons and organisational learning as strong feature of organisation’s practice capable of promoting stronger safety culture;and if lessons learned from other high-risk sectors can help inform risk-based decisions in organisations. Risk experts and by extension the nuclear sector, could have learned from past accident such as the Three Mile Island of 1979 and employ lessons learned to forestall future occurrences. Primary data was gathered via online, and research population are health and safety professionals from aviation, nuclear, and the oil and gas sectors. The sample size recruited are aviation (n = 59, 25%);nuclear (n = 124, 54%);and oil and gas (n = 49, 21%). Statistical Package for the Social Sciences (SPSS) software was used to analyse 232 responses used for this paper.
文摘BACKGROUNDPeriod poverty is a global health and social issue that needs to be addressed.It has been reported that many females compromise their education,employment,and social commitments during their menstruation days due to a number of reasons,including lack of access to toilets or menstrual products.AIM To provide a comprehensive understanding on period poverty,including outcomes associated with menstruation.METHODS All observational and randomised clinical trials reporting menstruation challenges,menstrual poverty and menstrual products were included.Our search strategy included multiple electronic databases of PubMed,Web of Science,ScienceDirect,ProQuest and EMBASE.Studies published in a peer review journal in English between the 30th of April 1980 and the 30th of April 2022 were included.The Newcastle-Ottawa Scale was used to assess the risk of bias of the systematic included studies.Pooled odds ratios(ORs)together with 95%confidence intervals(CIs)are reported overall and for sub-groups.RESULTS A total of 80 studies were systematically selected,where 38 were included in the meta-analysis.Of the 38 studies,28 focused on children and young girls(i.e.,10-24 years old)and 10 included participants with a wider age range of 15-49 years.The prevalence of using disposable sanitary pads was 45%(95%CI:0.35-0.58).The prevalence of menstrual education pre-menarche was 68%(95%CI:0.56-0.82).The prevalence of good menstrual hygiene management(MHM)was 39%(95%CI:0.25-0.61).Women in rural areas(OR=0.30,95%CI:0.13-0.69)were 0.70 times less likely to have good MHM practices than those living in urban areas.CONCLUSION There was a lack of evidence,especially from low-and middle-income countries.Further research to better understand the scope and prevalence of period poverty should be considered.This will enable the development of improved policies to increase access to menstrual products and medical support where necessary.
文摘Liver fibrosis is characterised by excessive deposition of extracellular matrix that interrupts normal liver functionality. It is a pathological stage in several untreated chronic liver diseases such as the iron overload syndrome hereditary haemochromatosis, viral hepatitis, alcoholic liver disease, non-alcoholic fatty liver disease, non-alcoholic steatohepatitis and diabetes. Interestingly, regardless of the aetiology, iron-loading is frequently observed in chronic liver diseases. Excess iron can feed the Fenton reaction to generate unquenchable amounts of free radicals that cause grave cellular and tissue damage and thereby contribute to fibrosis. Moreover, excess iron can induce fibrosis-promoting signals in the parenchymal and non-parenchymal cells, which accelerate disease progression and exacerbate liver pathology. Fibrosis regression is achievable following treatment, but if untreated or unsuccessful, it can progress to the irreversible cirrhotic stage leading to organ failure and hepatocellular carcinoma, where resection or transplantation remain the only curative options. Therefore,understanding the role of iron in liver fibrosis is extremely essential as it can help in formulating iron-related diagnostic, prognostic and treatment strategies. These can be implemented in isolation or in combination with the current approaches to prepone detection, and halt or decelerate fibrosis progression before it reaches the irreparable stage. Thus, this review narrates the role of iron in liver fibrosis. It examines the underlying mechanisms by which excess iron can facilitate fibrotic responses. It describes the role of iron in various clinical pathologies and lastly,highlights the significance and potential of iron-related proteins in the diagnosis and therapeutics of liver fibrosis.
基金funding from the EU Smarter project(PEOPLE-2013-IAPP-610675)
文摘To achieve zero-defect production during computer numerical control(CNC)machining processes,it is imperative to develop effective diagnosis systems to detect anomalies efficiently.However,due to the dynamic conditions of the machine and tooling during machining processes,the relevant diagnosis systems currently adopted in industries are incompetent.To address this issue,this paper presents a novel data-driven diagnosis system for anomalies.In this system,power data for condition monitoring are continuously collected during dynamic machining processes to support online diagnosis analysis.To facilitate the analysis,preprocessing mechanisms have been designed to de-noise,normalize,and align the monitored data.Important features are extracted from the monitored data and thresholds are defined to identify anomalies.Considering the dynamic conditions of the machine and tooling during machining processes,the thresholds used to identify anomalies can vary.Based on historical data,the values of thresholds are optimized using a fruit fly optimization(FFO)algorithm to achieve more accurate detection.Practical case studies were used to validate the system,thereby demonstrating the potential and effectiveness of the system for industrial applications.
基金supported by the National Key Research and Development Program of China(Grant No.2016YFE0122500)the Researcher Links Fund,British Council(Grant No.227109770)+1 种基金the National Natural Science Foundation of China(Grants No.5151101425 and 51579166)the Open Research Fund from the State Key Laboratory of Hydraulics and Mountain River Engineering,Sichuan University(Grants No.SKHL1601 and SKHL1602)
文摘Increased urbanisation,economic growth,and long-term climate variability have made both the UK and China more susceptible to urban and river flooding,putting people and property at increased risk.This paper presents a review of the current flooding challenges that are affecting the UK and China and the actions that each country is undertaking to tackle these problems.Particular emphases in this paper are laid on(1)learning from previous flooding events in the UK and China,and(2)which management methodologies are commonly used to reduce flood risk.The paper concludes with a strategic research plan suggested by the authors,together with proposed ways to overcome identified knowledge gaps in flood management.Recommendations briefly comprise the engagement of all stakeholders to ensure a proactive approach to land use planning,early warning systems,and water-sensitive urban design or redesign through more effective policy,multi-level flood models,and data driven models of water quantity and quality.
文摘In the present paper, the isogeometric analysis(IGA) of free-form planar curved beams is formulated based on the nonlinear Timoshenko beam theory to investigate the large deformation of beams with variable curvature. Based on the isoparametric concept, the shape functions of the field variables(displacement and rotation) in a finite element analysis are considered to be the same as the non-uniform rational basis spline(NURBS) basis functions defining the geometry. The validity of the presented formulation is tested in five case studies covering a wide range of engineering curved structures including from straight and constant curvature to variable curvature beams. The nonlinear deformation results obtained by the presented method are compared to well-established benchmark examples and also compared to the results of linear and nonlinear finite element analyses. As the nonlinear load-deflection behavior of Timoshenko beams is the main topic of this article, the results strongly show the applicability of the IGA method to the large deformation analysis of free-form curved beams. Finally, it is interesting to notice that, until very recently, the large deformations analysis of free-form Timoshenko curved beams has not been considered in IGA by researchers.
基金We appreciate the funding/financial support received from the Higher Education Innovation Fund(HEIF)of De Montfort University,Leicester,UK,under Research Project No.0043.06.
文摘The major drawback associated with PEEK implants is their biologically inert surface,which caused unsatisfactory cellular response and poor adhesion between the implants and surrounding soft tissues against proper bone growth.In this study,polyetheretherketone(PEEK)was incorporated with calcium hydroxyapatite(cHAp)to fabricate a PEEK-cHAp biocomposite,using the fused deposition modeling(FDM)method and a surface treatment strategy to create microporous architectures onto the filaments of PEEK lattice scaffold.Also,nanostructure and morphological tests of the PEEK-cHAp biocomposite were modeled and analyzed on the FDM-printed PEEK-cHAp biocomposite sample to evaluate its mechanical and thermal strengths as well as in vitro cytotoxicity via a scanning electron microscope(SEM).A technique was used innovatively to create and investigate the porous nanostructure of the PEEK with controlled pore size and distribution to promote cell penetration and biological integration of the PEEK-cHAp into the tissue.In vivo tests demonstrated that the surface-treated micropores facilitated the adhesion of newly regenerated soft tissues to form tight implant-tissue interfacial bonding between the cHAp and PEEK.The results of the cell culture depicted that PEEK-cHAp exhibited better cell proliferation attachment spreading and higher alkaline phosphatase activity than PEEK alone.Apatite islands formed on the PEEK-cHAp composite after immersion in simulated body fluid of Dulbecco’s modified Eagle medium(DMEM)for 14 days and grew continuously with more or extended periods.The microstructure treatment of the crystallinity of PEEK was comparatively and significantly different from the PEEK-cHAp sample,indicating a better treatment of PEEK-cHAp.The in vitro results obtained from the PEEK-cHAp biocomposite material showed its biodegradability and performance suitability for bone implants.This study has potential applications in the field of biomedical engineering to strengthen the conceptual knowledge of FDM and medical implants fabricated from PEEK-cHAp biocomposite materials.
文摘The mechanical performances and water retention characteristics of clays,stabilised by partial substitution of cement with by-products and inclusion of a nanotechnology-based additive called RoadCem(RC),are studied in this research.The unconfined compression tests and one-dimensional oedometer swelling were performed after 7 d of curing to understand the influence of addition of 1%of RC material in the stabilised soils with the cement partially replaced by 49%,59%and 69%of ground granulated blast furnace slag(GBBS)or pulverised fuel ash(PFA).The moisture retention capacity of the stabilised clays was also explored using the soil-water retention curve(SWRC)from the measured suctions.Results confirmed an obvious effect of the use of RC with the obtained strength and swell properties of the stabilised clays suitable for road application at 50%replacement of cement.This outcome is associated with the in-depth and penetrating hydration of the cementitious materials by the RC and water which results in the production of needle-like matrix with interlocking filaments e a phenomenon referred to as the‘wrapping’effect.On the other hand,the SWRC used to describe the water holding capacity and corresponding swell mechanism of clays stabilised by a proportion of RC showed a satisfactory response.The moisture retention of the RC-modified clays was initially higher but reduced subsequently as the saturation level increased with decreasing suction.This phenomenon confirmed that clays stabilised by including the RC are water-proof in nature,thus ensuring reduced porosity and suction even at reduced water content.Overall,the stabilised clays with the combination of cement,GGBS and RC showed a better performance compared to those with the PFA included.