Background: Breast cancer is the dominant cancer in women in both developed and developing countries. The objective of this study was to assess the knowledge, attitudes, practices and factors associated with early bre...Background: Breast cancer is the dominant cancer in women in both developed and developing countries. The objective of this study was to assess the knowledge, attitudes, practices and factors associated with early breast cancer screening among women in the Municipality of Abomey-Calavi in Benin. Methods: This was a cross-sectional, descriptive, analytical study with prospective data collection from October 1 to 8, 2018, involving 1740 women in the Municipality of Abomey-Calavi, aged 18 years or older and selected by WHO four-stage random cluster sampling. Consenting women who were mentally competent, 18 years of age or older at the time of the survey, and residing continuously in the Municipality of Abomey-Calavi for the last six months prior to the survey were included. On the other hand, women who belonged to a breast cancer prevention service, women in whom secondary screening was noted, or non-consenting women were not included. The initial minimum size was estimated by the Schwartz formula with a cluster effect of k = 2. Information was collected by questionnaire survey, entered with Epidata 3.1. Fr and analyzed with R Studio 3.5.1. software. Results: The mean age of the women surveyed was 32.0 ± 11.5 years with a range of 18 and 71 years. Regarding knowledge, the clinical manifestation known by the majority of women was the presence of a nodule (68.50%). In the series, 1308 (75.17%) declared having heard about breast cancer once before, either on the radio, television or from friends and 726 (55.50%) had heard about breast cancer screening. Five hundred and twelve (70.52%) of the 726 who had heard of breast cancer said they knew that breast cancer could be screened earlier. Breast self-examination was the most cited screening method (67.58%). The disease is of natural origin according to 37.84% of them. Regarding attitudes and practices, the prevalence of early breast cancer screening was 12.93%, of which 11.67% declared that they had checked themselves to know whether they were carriers of the disease or not. The main means of the early screening used was breast self-examination (85.78%). Factors associated with early breast cancer screening found in multivariate analysis were age (≤50 years), education level (increasingly higher), marital status (married/coupled), place of residence (downtown), and socioeconomic level (average/high). Conclusion: The frequency of early breast cancer screening among women is still low in the municipality of Abomey-Calavi, although they have a good knowledge of the disease. This raises the need to strengthen awareness of early breast cancer screening.展开更多
The catalytic activity of Cu-ZSM-5 in trichloroethylene （TCE） combustion increases with the increasing skeletal Cu amount and however decreases with the increase of surface amorphous CuO, which is detected by infrar...The catalytic activity of Cu-ZSM-5 in trichloroethylene （TCE） combustion increases with the increasing skeletal Cu amount and however decreases with the increase of surface amorphous CuO, which is detected by infrared spectroscopy （IR） and diffuse reflectance ultraviolet-visible spectroscopy （DRS-UV-vis）, therefore the skeletal Cu species are concluded to be the active sites for the TCE combustion.展开更多
Daily temperature data from 599 stations across China for the years 1961 to 2007 were used to analyze the changes in the natural regional boundaries. The results show that the accumulated temperature ≥10℃ and its du...Daily temperature data from 599 stations across China for the years 1961 to 2007 were used to analyze the changes in the natural regional boundaries. The results show that the accumulated temperature ≥10℃ and its duration changed dramatically from the end of 1990s to the early 21 st century. The amplitude of natural regional boundaries was greater in the 21st century than it was in the 20th century. In the eastern region of China, the climatic zones were migrating generally northward, with the northern edge of the subtropical zone and the eastern section of the warm temperate zone showing an obvious northward shift of up to 1-3° of latitude. The climatic zones moved south in the Qinghal-Tibet Plateau, western Inner Mongolia, and some areas of western Xinjiang, and slightly to the north in other parts of the western region.展开更多
Introduction: Body Dysmorphia Disorder (BDD) is a mental disorder characterized by an obsessive focus on a perceived defect in appearance. This disorder can be dangerous or life-threatening. Hence, there is the need f...Introduction: Body Dysmorphia Disorder (BDD) is a mental disorder characterized by an obsessive focus on a perceived defect in appearance. This disorder can be dangerous or life-threatening. Hence, there is the need for special attention. Objective: The aim of this study was to determine the prevalence of Body Dysmorphia Disorder (BDD) and to identify the factors associated with it. Methods: This was a descriptive and analytical cross-sectional study that took place from December 2020 to October 2021, with a census of all medical students enrolled at the University of Parakou for the 2020-2021 academic year and who volunteered to participate. DSM 5 diagnostic criteria were used to assess BDD, and the Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS) was used to assess its severity. Results: A total of 669 people were included in the study. The prevalence of probable cases of BDD was 10.31%. Gender (female) (OR = 2.49;IC 95%: [1.45 - 4.26];p < 0.001), trauma with cosmetic sequelae (OR = 2.95;IC 95%: [1.27 - 6.91];p = 0.012), depressive disorders (OR = 2.4;IC 95%: [1.12 - 5.15];p = 0.025), mockery/teasing or negative comments about physique (OR = 3.54;IC 95%: [2.06 - 6.12];p < 0.001), a succession of sentimental disappointments (OR = 2.89;IC 95%: [1.33 - 6.30];p = 0.008), and the importance attached to physical appearance (OR = 0.5;IC 95%: [0.31 - 0.82];p = 0.005) are associated with BDD. Its consequences are serious, with an altered quality of life that can lead to dropping out of school and suicidal ideation or behavior. Conclusion: Although little studied and little diagnosed, Body Dysmorphia Disorder (BDD) is a reality in the student environment of northern Benin. Further studies are needed to more define BDD in the Beninese socio-cultural context.展开更多
Plant genomics and crop breeding are at the intersection of biotechnology and information technology.Driven by a combination of highthroughput sequencing,molecular biology and data science,great advances have been mad...Plant genomics and crop breeding are at the intersection of biotechnology and information technology.Driven by a combination of highthroughput sequencing,molecular biology and data science,great advances have been made in omics technologies at every step along the central dogma,especially in genome assembling,genome annotation,epigenomic profiling,and transcriptome profiling.These advances further revolutionized three directions of development.One is genetic dissection of complex traits in crops,along with genomic prediction and selection.The second is comparative genomics and evolution,which open up new opportunities to depict the evolutionary constraints of biological sequences for deleterious variant discovery.The third direction is the development of deep learning approaches for the rational design of biological sequences,especially proteins,for synthetic biology.All three directions of development serve as the foundation for a new era of crop breeding where agronomic traits are enhanced by genome design.展开更多
The nickel-promoted Cu-containing catalysts （CuxNiy-MgAlO） for furfural （FFR） hydrogenation were prepared from the hydrotalcite-like precursors, and characterized by X-ray powder diffraction, inductively-coupled p...The nickel-promoted Cu-containing catalysts （CuxNiy-MgAlO） for furfural （FFR） hydrogenation were prepared from the hydrotalcite-like precursors, and characterized by X-ray powder diffraction, inductively-coupled plasma atomic emission spectroscopy, N2 adsorption-desorption, UV-Vis diffuse reflectance spectra and temperatureprogrammed reduction with H2 in the present work. The obtained catalysts were observed to exhibit a better catalytic property than the corresponding Cu-MgAlO or Ni-MgAlO samples in FFR hydrogenation, and the CuNi-MgAIO catalyst with the actual Cu and Ni loadings of 12.5 wt% and 4.5 wt%, respectively, could give the highest FFR conversion （93.2%） and furfuryl alcohol selectivity （89.2%）. At the same time, Cu~ species from the reduction of Cu2＋ ions in spinel phases were deduced to be more active for FFR hydrogenation.展开更多
文摘Background: Breast cancer is the dominant cancer in women in both developed and developing countries. The objective of this study was to assess the knowledge, attitudes, practices and factors associated with early breast cancer screening among women in the Municipality of Abomey-Calavi in Benin. Methods: This was a cross-sectional, descriptive, analytical study with prospective data collection from October 1 to 8, 2018, involving 1740 women in the Municipality of Abomey-Calavi, aged 18 years or older and selected by WHO four-stage random cluster sampling. Consenting women who were mentally competent, 18 years of age or older at the time of the survey, and residing continuously in the Municipality of Abomey-Calavi for the last six months prior to the survey were included. On the other hand, women who belonged to a breast cancer prevention service, women in whom secondary screening was noted, or non-consenting women were not included. The initial minimum size was estimated by the Schwartz formula with a cluster effect of k = 2. Information was collected by questionnaire survey, entered with Epidata 3.1. Fr and analyzed with R Studio 3.5.1. software. Results: The mean age of the women surveyed was 32.0 ± 11.5 years with a range of 18 and 71 years. Regarding knowledge, the clinical manifestation known by the majority of women was the presence of a nodule (68.50%). In the series, 1308 (75.17%) declared having heard about breast cancer once before, either on the radio, television or from friends and 726 (55.50%) had heard about breast cancer screening. Five hundred and twelve (70.52%) of the 726 who had heard of breast cancer said they knew that breast cancer could be screened earlier. Breast self-examination was the most cited screening method (67.58%). The disease is of natural origin according to 37.84% of them. Regarding attitudes and practices, the prevalence of early breast cancer screening was 12.93%, of which 11.67% declared that they had checked themselves to know whether they were carriers of the disease or not. The main means of the early screening used was breast self-examination (85.78%). Factors associated with early breast cancer screening found in multivariate analysis were age (≤50 years), education level (increasingly higher), marital status (married/coupled), place of residence (downtown), and socioeconomic level (average/high). Conclusion: The frequency of early breast cancer screening among women is still low in the municipality of Abomey-Calavi, although they have a good knowledge of the disease. This raises the need to strengthen awareness of early breast cancer screening.
基金financially supported by the developing & scientific foundation of Chengdu University of Information Technology (No.KYTZ20060902)Sichuan Provincial Department of Education (No.2006C032).
文摘The catalytic activity of Cu-ZSM-5 in trichloroethylene （TCE） combustion increases with the increasing skeletal Cu amount and however decreases with the increase of surface amorphous CuO, which is detected by infrared spectroscopy （IR） and diffuse reflectance ultraviolet-visible spectroscopy （DRS-UV-vis）, therefore the skeletal Cu species are concluded to be the active sites for the TCE combustion.
基金supported by the National Natural Science Foundation of China (Grant No.40875053)
文摘Daily temperature data from 599 stations across China for the years 1961 to 2007 were used to analyze the changes in the natural regional boundaries. The results show that the accumulated temperature ≥10℃ and its duration changed dramatically from the end of 1990s to the early 21 st century. The amplitude of natural regional boundaries was greater in the 21st century than it was in the 20th century. In the eastern region of China, the climatic zones were migrating generally northward, with the northern edge of the subtropical zone and the eastern section of the warm temperate zone showing an obvious northward shift of up to 1-3° of latitude. The climatic zones moved south in the Qinghal-Tibet Plateau, western Inner Mongolia, and some areas of western Xinjiang, and slightly to the north in other parts of the western region.
文摘Introduction: Body Dysmorphia Disorder (BDD) is a mental disorder characterized by an obsessive focus on a perceived defect in appearance. This disorder can be dangerous or life-threatening. Hence, there is the need for special attention. Objective: The aim of this study was to determine the prevalence of Body Dysmorphia Disorder (BDD) and to identify the factors associated with it. Methods: This was a descriptive and analytical cross-sectional study that took place from December 2020 to October 2021, with a census of all medical students enrolled at the University of Parakou for the 2020-2021 academic year and who volunteered to participate. DSM 5 diagnostic criteria were used to assess BDD, and the Yale-Brown Obsessive-Compulsive Scale Modified for Body Dysmorphic Disorder (BDD-YBOCS) was used to assess its severity. Results: A total of 669 people were included in the study. The prevalence of probable cases of BDD was 10.31%. Gender (female) (OR = 2.49;IC 95%: [1.45 - 4.26];p < 0.001), trauma with cosmetic sequelae (OR = 2.95;IC 95%: [1.27 - 6.91];p = 0.012), depressive disorders (OR = 2.4;IC 95%: [1.12 - 5.15];p = 0.025), mockery/teasing or negative comments about physique (OR = 3.54;IC 95%: [2.06 - 6.12];p < 0.001), a succession of sentimental disappointments (OR = 2.89;IC 95%: [1.33 - 6.30];p = 0.008), and the importance attached to physical appearance (OR = 0.5;IC 95%: [0.31 - 0.82];p = 0.005) are associated with BDD. Its consequences are serious, with an altered quality of life that can lead to dropping out of school and suicidal ideation or behavior. Conclusion: Although little studied and little diagnosed, Body Dysmorphia Disorder (BDD) is a reality in the student environment of northern Benin. Further studies are needed to more define BDD in the Beninese socio-cultural context.
基金supported by the National Key Research and Development Program of China(2022YFD1201100)the National Natural Science Foundation of China(32071464)+1 种基金Chinese Universities Scientific Fund(2023RC002)the 2115 Talent Development Program of China Agricultural University.
文摘Plant genomics and crop breeding are at the intersection of biotechnology and information technology.Driven by a combination of highthroughput sequencing,molecular biology and data science,great advances have been made in omics technologies at every step along the central dogma,especially in genome assembling,genome annotation,epigenomic profiling,and transcriptome profiling.These advances further revolutionized three directions of development.One is genetic dissection of complex traits in crops,along with genomic prediction and selection.The second is comparative genomics and evolution,which open up new opportunities to depict the evolutionary constraints of biological sequences for deleterious variant discovery.The third direction is the development of deep learning approaches for the rational design of biological sequences,especially proteins,for synthetic biology.All three directions of development serve as the foundation for a new era of crop breeding where agronomic traits are enhanced by genome design.
文摘The nickel-promoted Cu-containing catalysts （CuxNiy-MgAlO） for furfural （FFR） hydrogenation were prepared from the hydrotalcite-like precursors, and characterized by X-ray powder diffraction, inductively-coupled plasma atomic emission spectroscopy, N2 adsorption-desorption, UV-Vis diffuse reflectance spectra and temperatureprogrammed reduction with H2 in the present work. The obtained catalysts were observed to exhibit a better catalytic property than the corresponding Cu-MgAlO or Ni-MgAlO samples in FFR hydrogenation, and the CuNi-MgAIO catalyst with the actual Cu and Ni loadings of 12.5 wt% and 4.5 wt%, respectively, could give the highest FFR conversion （93.2%） and furfuryl alcohol selectivity （89.2%）. At the same time, Cu~ species from the reduction of Cu2＋ ions in spinel phases were deduced to be more active for FFR hydrogenation.
