Africa is the world region that is most affected by malaria. Among the therapies used, injectable quinine is considered to be one of the effective antimalarial drug, however non-quality assured antimalarials clearly h...Africa is the world region that is most affected by malaria. Among the therapies used, injectable quinine is considered to be one of the effective antimalarial drug, however non-quality assured antimalarials clearly have a strong market penetration across Africa. To overcome this problem, it becomes more and more necessary to set up quantitative and qualitative analysis system for antimalarial quality control. The objective of the present investigation is an attempt to use customized multispectral microscope equipped with UV-Visible lasers for injectable quinine quality assurance control routinely. For that, we have established the calibration curve of quinine solution concentration as a function of area under light intensity histogram crossing the solution. From this calibration curve, we can check the conformity of any injectable quinine according to the pharmacopoeia involved. The proposed technique is a promising alternative for drug quality control routinely.展开更多
In this work, an inexpensive and environmentally friendly natural adsorbent obtained from shelled (GD) and unshelled (GND) </span><span style="font-family:""><i></span><i>&...In this work, an inexpensive and environmentally friendly natural adsorbent obtained from shelled (GD) and unshelled (GND) </span><span style="font-family:""><i></span><i><span style="font-family:"">Moringa oleifera</span></i><i><span style="font-family:""></i></span></i><i><span style="font-family:""> </span></i><span style="font-family:"">seeds was used for copper adsorption from aqueous solutions. A series of experiments were performed to assess the parameters influencing the adsorption pheno<span>menon such as pH, adsorbent mass, adsorption equilibrium time and</span> temper<span>ature. The kinetic results of adsorption described a pseudo-second order</span> mod<span>el. The adsorption isotherms are satisfactorily described by the Langmuir</span> mathematical model. The thermodynamic data revealed a spontaneous and endothermic adsorption phenomenon. The level of copper in surface water be<span>fore and after addition of moringa powders was carried out to verify the effectiveness of the adsorbent. A maximum adsorption rate of 51.28% and </span>61.96% was obtained with GD and GND powders respectively. </span><span style="font-family:""><i></span><i><span style="font-family:"">Moringa oleifera</span></i><i><span style="font-family:""></i></span></i><span style="font-family:""> seed powders are an effective alternative for the removal of copper from surface water.展开更多
<i><span style="font-family:;" "=""><i></i></span><i><span style="font-family:;" "="">Moringa oleifera</span></i>...<i><span style="font-family:;" "=""><i></i></span><i><span style="font-family:;" "="">Moringa oleifera</span></i><i><span style="font-family:;" "=""></span></i></i><span style="font-family:;" "=""> is an edible plant cultivated throughout the tropical belt. It belongs to the family Moringaceae and is one of its 14 known species. This paper presents a synthesis of the main factors responsible for the retention of trace metal elements (TMEs) by </span><span style="font-family:;" "=""><i></i></span><i><i><span style="font-family:;" "="">Moringa oleifera</span></i><i><span style="font-family:;" "=""></span></i></i><span style="font-family:;" "=""> seed powder, a natural adsorbent. The five main factors studied are metal concentration, solution pH, adsorbent particle size, adsorbent dose and adsorbent/adsorbate contact time. Through these factors, we present the optimal conditions for removal of these TMEs, as well as adsorption isotherm models appropriate for the conditions of retention of these metal cations by the adsorbent. The times of 20 min (GD) and 50 min (GND) are the equilibrium times obtained in our study. An optimal adsorbent mass (GD and GND powders) of 4.5 g was found. 20</span><span style="font-family:;" "="">%</span><span style="font-family:;" "=""> to 97% abatement is observed for average pH values between 6 and 8. The coefficients of determination (R2) obtained (0.972</span><span style="font-family:;" "="">,</span><span style="font-family:;" "=""> 0.963</span><span style="font-family:;" "="">,</span><span style="font-family:;" "=""> 0.991 and 0.799) during the isotherm experiments carried out at 20</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C, 30</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C, 40</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C and 50</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C are close to 1. Also, the separation factor (R<sub>L</sub>), an essential characteristic of the Langmuir isotherm whose values are between 0 and 1, attest to the applicability of the Langmuir isotherm model to fit the experimental data of copper adsorption by Moringa powders.</span><span style="font-family:;" "=""> In this paper, we are particularly interested in the following TMEs (Mn, Ni, Cr, Cu, Cd, Co, Pb, Fe, Zn, Ag).</span>展开更多
文摘Africa is the world region that is most affected by malaria. Among the therapies used, injectable quinine is considered to be one of the effective antimalarial drug, however non-quality assured antimalarials clearly have a strong market penetration across Africa. To overcome this problem, it becomes more and more necessary to set up quantitative and qualitative analysis system for antimalarial quality control. The objective of the present investigation is an attempt to use customized multispectral microscope equipped with UV-Visible lasers for injectable quinine quality assurance control routinely. For that, we have established the calibration curve of quinine solution concentration as a function of area under light intensity histogram crossing the solution. From this calibration curve, we can check the conformity of any injectable quinine according to the pharmacopoeia involved. The proposed technique is a promising alternative for drug quality control routinely.
文摘In this work, an inexpensive and environmentally friendly natural adsorbent obtained from shelled (GD) and unshelled (GND) </span><span style="font-family:""><i></span><i><span style="font-family:"">Moringa oleifera</span></i><i><span style="font-family:""></i></span></i><i><span style="font-family:""> </span></i><span style="font-family:"">seeds was used for copper adsorption from aqueous solutions. A series of experiments were performed to assess the parameters influencing the adsorption pheno<span>menon such as pH, adsorbent mass, adsorption equilibrium time and</span> temper<span>ature. The kinetic results of adsorption described a pseudo-second order</span> mod<span>el. The adsorption isotherms are satisfactorily described by the Langmuir</span> mathematical model. The thermodynamic data revealed a spontaneous and endothermic adsorption phenomenon. The level of copper in surface water be<span>fore and after addition of moringa powders was carried out to verify the effectiveness of the adsorbent. A maximum adsorption rate of 51.28% and </span>61.96% was obtained with GD and GND powders respectively. </span><span style="font-family:""><i></span><i><span style="font-family:"">Moringa oleifera</span></i><i><span style="font-family:""></i></span></i><span style="font-family:""> seed powders are an effective alternative for the removal of copper from surface water.
文摘<i><span style="font-family:;" "=""><i></i></span><i><span style="font-family:;" "="">Moringa oleifera</span></i><i><span style="font-family:;" "=""></span></i></i><span style="font-family:;" "=""> is an edible plant cultivated throughout the tropical belt. It belongs to the family Moringaceae and is one of its 14 known species. This paper presents a synthesis of the main factors responsible for the retention of trace metal elements (TMEs) by </span><span style="font-family:;" "=""><i></i></span><i><i><span style="font-family:;" "="">Moringa oleifera</span></i><i><span style="font-family:;" "=""></span></i></i><span style="font-family:;" "=""> seed powder, a natural adsorbent. The five main factors studied are metal concentration, solution pH, adsorbent particle size, adsorbent dose and adsorbent/adsorbate contact time. Through these factors, we present the optimal conditions for removal of these TMEs, as well as adsorption isotherm models appropriate for the conditions of retention of these metal cations by the adsorbent. The times of 20 min (GD) and 50 min (GND) are the equilibrium times obtained in our study. An optimal adsorbent mass (GD and GND powders) of 4.5 g was found. 20</span><span style="font-family:;" "="">%</span><span style="font-family:;" "=""> to 97% abatement is observed for average pH values between 6 and 8. The coefficients of determination (R2) obtained (0.972</span><span style="font-family:;" "="">,</span><span style="font-family:;" "=""> 0.963</span><span style="font-family:;" "="">,</span><span style="font-family:;" "=""> 0.991 and 0.799) during the isotherm experiments carried out at 20</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C, 30</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C, 40</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C and 50</span><span style="font-family:;" "="">°</span><span style="font-family:;" "="">C are close to 1. Also, the separation factor (R<sub>L</sub>), an essential characteristic of the Langmuir isotherm whose values are between 0 and 1, attest to the applicability of the Langmuir isotherm model to fit the experimental data of copper adsorption by Moringa powders.</span><span style="font-family:;" "=""> In this paper, we are particularly interested in the following TMEs (Mn, Ni, Cr, Cu, Cd, Co, Pb, Fe, Zn, Ag).</span>