DCM 执著电商

如今电商领域后起之秀已经不具备时间优势，大而全的公司能成功的或许很鱿反而是垂直领域的B2C更有机会。

英国新数据保护法案:改革计划

2017年8月7日,英国数字、文化、媒体和体育部发布了《英国新数据保护法案:改革计划》(A New Data Protection Bill:Our Planned Reforms),表明即将通过新的《数据保护法》来强化数字经济时代的数据保护。就改革的总体目标来说,新法案致力于获得公众信任、促进未来交易以及确保数据安全。在内容上,新法案加强了对个人数据的保护,尤其是增加了数据可携带权和被遗忘权的规定,强化了机构的数据保护责任,实行严格的行政监管,以及增进与刑事司法机构之间的合作。在具体的实施方面,新法案确保与欧盟关于数据保护的条例和指令进行协调,又根据英国自身的情况在未成年人保护的年龄门槛和国家数据安全等方面进行相应的变通处理。就未来的发展而言,数据对于经济增长的作用不断加强,即便是在可能“脱欧”的背景下,网络安全与数据保护仍然是英国面临的重要议题。

2017国际数字医学会数字中医药分会年会暨第二届数字中医药学术交流会

（2017·中国广州琶洲）国际数字医学会数字中医药分会是在国际一级学会——国际数字医学会名誉会长、Digital Chinese Medicine（《数字中医药》,以下简称DCM）杂志主编钟世镇院士的倡导下,由湖南中医药大学和DCM杂志联合中国科学院、中南大学、复旦大学等单位及全国各高等中医药院校共同发起成立的国家级学会。

网桥

澳大利亚DCM公司设计的墨尔本新港区网桥以蜿蜓独特的造型连接了残留的老桥与新开发的河岸。文章简要介绍了网桥的建设背景、设计手法、施工过程以及建成意义。

A Study on Changes of the Plasma Endothelin Level in Patients with Dilated Cardiomyopathy

Objectives To evaluate the changes of the plasma endothelin level in patients with dilated cardiomyopathy, and to investigate the relationship between the plasma endothelin level and the severity of heart failure, heart size, left ventricular function and with or not with pulmonary arterial hypertension; the changes of the plasma endothelin level before and after treatment. Methods The plasma endothelin level of 30 patients with DCM, 30 healthy control subjects, and their LVEF, PAP, heart size, plasma endothelin level before and after treatment were determined. Results The plasma endothelin level in DCM group was significantly higher than that in control group ( 135.93 ± 70. 65pg/mL) vs(43.65 ± 12.07pg/mL), P < 0.05 ; there was a correlation between ET level and heart size ( r = O. 4580, P = 0. 0109 ) ; there was a significant negative correlation between LVEF of DCM and ET level( r = -0. 6922 ,P =0. 0021 ) ;and it was a significant positive correlation between ET level and pulmonary arterial hypertension (r = 0. 8974, P < 0. 0005). After treatment, the ET level decreased significantly than before in DCM group (129. 15 ± 43.93pg/mL) vs (63.12 ± 22.20pg/mL), P < 0.05. Conclusions Plasma ET level may be a new parameter of evaluating severity of heart failure, efficacy of therapy and prognosis.

EXPRESSION OF MHC-Ⅰ AND MHC-Ⅱ ANTIGENS IN ENDOMYOCARDIAL BIOPSIES FROM PATIENTS WITH VIRAL MYOCARDITIS AND CARDIOMYOPATHY

In situ expression of major histocompatibility complex (MHC) Ⅰ and Ⅱ antigens were examined in endomyocardial biopsy samples from 35 patients with viral myocarditis (VMC) and dilated cardiomyopathy (DCM). Increased expressions of these 2 antigens were observed on endocardia, capillary endothelia, dentritic and mononuclear cell membranes. The expression of sarcolemma was also found in specimens of VMC and DCM. Thus the abnormal expression of MHC is a new marker of autoimmune reactivity directed against cardiac structures.

数字中医药在中医药发展中的前景展望

近代以来,随着农业社会向工业社会转换,中医药开始停滞不前,凸显落后,中医药人却无法找到其发展的突破点。笔者立足发展的角度,从时代发展、学科融合创新、大数据驱动及产业与时俱进4个方面的要求探讨数字中医药研究在中医药发展上的紧迫性、重要性。

Closing the gap between atomic-scale lattice deformations and continuum elasticity

Crystal lattice deformations can be described microscopically by explicitly accounting for the position of atoms or macroscopically by continuum elasticity.In this work,we report on the description of continuous elastic fields derived from an atomistic representation of crystalline structures that also include features typical of the microscopic scale.Analytic expressions for strain components are obtained from the complex amplitudes of the Fourier modes representing periodic lattice positions,which can be generally provided by atomistic modeling or experiments.The magnitude and phase of these amplitudes,together with the continuous description of strains,are able to characterize crystal rotations,lattice deformations,and dislocations.Moreover,combined with the so-called amplitude expansion of the phase-field crystal model,they provide a suitable tool for bridging microscopic to macroscopic scales.This study enables the in-depth analysis of elasticity effects for macroscale and mesoscale systems taking microscopic details into account.

Towards a Versatile Photoreactive Platform for Biosensing Applications

An original interfacial hybrid cross-linker molecule combined electrochemical and photochemical properties by substitution of two functional groups,pyrene,and diazirine.The first group enables anchoring by strong p-stacking interaction or by electropolymerization onto multi-walled carbon nanotubes(MWCNT).The other photoreactive group allows the covalent link with biomolecules under long-wavelength UV illumination.Diazirine was chosen due to its ability to photogenerate high reactive radicals under UV irradiation.The photoreactivity of these immobilized nanostructured conductive surfaces was tested towards the covalent attachment of tyrosinase which is well known to oxidize a large range of phenolic compounds and its yield and availability was evaluated by amperometric measurements of catechol by using molecular dioxygen.The architecture exhibiting the best analytical characteristics obtained for catechol was then chosen to detect dopamine.

快手、58、唯品会背后的投资逻辑:懂的时候,要敢赌;不懂的时候,勿跟风

过去十几年的经历让我发现,越成功越成为你的绊脚石,因为大家对你的期望越来越高。一旦成功,外部压力增加,大家会说,你怎么投了那种公司?而其实现在非常强的公司,刚开始都名不见经传。价值发现:如何做好投资决策做投资有两种方法:一种是投前发现价值,一种是投后帮公司做得更好,或者说帮公司打造成一个独角兽.

Notes,outline and divergence times of Basidiomycota

The Basidiomycota constitutes a major phylum of the kingdom Fungi and is second in species numbers to the Ascomycota.The present work provides an overview of all validly published,currently used basidiomycete genera to date in a single document.An outline of all genera of Basidiomycota is provided,which includes 1928 currently used genera names,with 1263 synonyms,which are distributed in 241 families,68 orders,18 classes and four subphyla.We provide brief notes for each accepted genus including information on classification,number of accepted species,type species,life mode,habitat,distribution,and sequence information.Furthermore,three phylogenetic analyses with combined LSU,SSU,5.8s,rpb1,rpb2,and ef1 datasets for the subphyla Agaricomycotina,Pucciniomycotina and Ustilaginomycotina are conducted,respectively.Divergence time estimates are provided to the family level with 632 species from 62 orders,168 families and 605 genera.Our study indicates that the divergence times of the subphyla in Basidiomycota are 406-430 Mya,classes are 211-383 Mya,and orders are 99-323 Mya,which are largely consistent with previous studies.In this study,all phylogenetically supported families were dated,with the families of Agaricomycotina diverging from 27-178 Mya,Pucciniomycotina from 85-222 Mya,and Ustilaginomycotina from 79-177 Mya.Divergence times as additional criterion in ranking provide additional evidence to resolve taxonomic problems in the Basidiomycota taxonomic system,and also provide a better understanding of their phylogeny and evolution.