Three 2-{(3R, 7aS)-1, 1-disubstituted-tetrahydro-1H-pyrrolo [1,2-c][1,3]oxazol-3-yl} phenols have been synthesized from salicylaldehyde and amino alcohols derived from L-proline, and used as ligands hi enantioselectiv...Three 2-{(3R, 7aS)-1, 1-disubstituted-tetrahydro-1H-pyrrolo [1,2-c][1,3]oxazol-3-yl} phenols have been synthesized from salicylaldehyde and amino alcohols derived from L-proline, and used as ligands hi enantioselective addition of diethylzinc to aldehydes, the ee values of obtained secondary alcohols were found in the range of 0-90%.展开更多
基金Project supported by the Key Laboratory of Organic Syntheses,Jiangsu Province(No.T2109102).
文摘Three 2-{(3R, 7aS)-1, 1-disubstituted-tetrahydro-1H-pyrrolo [1,2-c][1,3]oxazol-3-yl} phenols have been synthesized from salicylaldehyde and amino alcohols derived from L-proline, and used as ligands hi enantioselective addition of diethylzinc to aldehydes, the ee values of obtained secondary alcohols were found in the range of 0-90%.
