AIM:To investigate the relationships between angiotensin converting enzyme gene polymorphism and lacunar infarction in patients with essential hypertension.METHODS:Polymerase chain reaction(PCR) was used to determine ...AIM:To investigate the relationships between angiotensin converting enzyme gene polymorphism and lacunar infarction in patients with essential hypertension.METHODS:Polymerase chain reaction(PCR) was used to determine the genotypes for an insertion/deletion polymorphism of 287 pb fragment of ACE gene in 50 healthy persons,50 patients with simple essential hypertension and 30 patients with essential hypertension and lacunar infarction.RESULTS:There was no significant difference of genotype and allele between healthy persons and patients with simple essential hypertension;but there was significant difference of D allele and DD genotype of ACE gene between esential hypertensive patients with lacunar infarction and patients with simple essential hypertension and healthy persons.CONCLUSION:There is a significant relation between ACE gene polymorphism and essential hypertensive patients with lacunar infarction.展开更多
A 36-year old female patient was admitted to our hospital in October 2005, with symptoms of cough and phlegmatic stagnation plus chest distress for over 5 months. She had received an X-ray examination at a local hospi...A 36-year old female patient was admitted to our hospital in October 2005, with symptoms of cough and phlegmatic stagnation plus chest distress for over 5 months. She had received an X-ray examination at a local hospital before her hospitalization, and it was Shown that there was a small round-like pulmonary focus. No improvement was found after a pre-antiinflammatory treatment for the cough.展开更多
文摘AIM:To investigate the relationships between angiotensin converting enzyme gene polymorphism and lacunar infarction in patients with essential hypertension.METHODS:Polymerase chain reaction(PCR) was used to determine the genotypes for an insertion/deletion polymorphism of 287 pb fragment of ACE gene in 50 healthy persons,50 patients with simple essential hypertension and 30 patients with essential hypertension and lacunar infarction.RESULTS:There was no significant difference of genotype and allele between healthy persons and patients with simple essential hypertension;but there was significant difference of D allele and DD genotype of ACE gene between esential hypertensive patients with lacunar infarction and patients with simple essential hypertension and healthy persons.CONCLUSION:There is a significant relation between ACE gene polymorphism and essential hypertensive patients with lacunar infarction.
文摘A 36-year old female patient was admitted to our hospital in October 2005, with symptoms of cough and phlegmatic stagnation plus chest distress for over 5 months. She had received an X-ray examination at a local hospital before her hospitalization, and it was Shown that there was a small round-like pulmonary focus. No improvement was found after a pre-antiinflammatory treatment for the cough.
