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A Novel Segment White Matter Hyperintensities Approach for Detecting Alzheimer
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作者 Antonitta Eileen Pious U.K.Sridevi 《Computer Systems Science & Engineering》 SCIE EI 2023年第3期2715-2726,共12页
Segmentation has been an effective step that needs to be done before the classification or detection of an anomaly like Alzheimer’s on a brain scan.Segmentation helps detect pixels of the same intensity or volume and... Segmentation has been an effective step that needs to be done before the classification or detection of an anomaly like Alzheimer’s on a brain scan.Segmentation helps detect pixels of the same intensity or volume and group them together as one class or region,where in that particular region of interest(ROI)can be concentrated on,rather than focusing on the entire image.In this paper White Matter Hyperintensities(WMH)is taken as a strong biomarker that supports and determines the presence of Alzheimer’s.As thefirst step a proper segmentation of the lesions has to be carried out.As pointed out in various other research papers,when the WMH area is very small or in places like the Septum Pellucidum the detection of the lesion is hard tofind.To overcome such problem areas a very optimized and accurate Threshold would be required to have a precise segmentation to detect the area of localization.This would help in proper detection and classification of the Anomaly.In this paper an elaborate comparison of various thresholding techniques has been done for segmentation.A novel idea for detection of Alzheimer’s has been presented in this paper,which encompasses the effectiveness of an optimized and adaptive technique.The Unet architecture has been taken as the baseline model with an adaptive kernel model embedded within the architecture.Various state-of-the-art technologies have been used with the dataset and a comparative study has been presented with the current architecture used in the paper.The lesion segmentation in narrow areas has accurately been detected compared to the other models and the number of false positives has been reduced to a great extent. 展开更多
关键词 Alzheimer’s adaptive threshold deep learning SEGMENTATION
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Optimal control of alcoholism spreading through awareness over multiplex network
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作者 Padmavathi Ramamoorthi Senthil Kumar Muthukrishnan 《International Journal of Biomathematics》 SCIE 2021年第6期33-58,共26页
This paper proposes the SISRS epidemic model to represent alcohol addiction among people.The spreading of alcohol addiction is controlled by creating awareness among the people and also by treating them to overcome it... This paper proposes the SISRS epidemic model to represent alcohol addiction among people.The spreading of alcohol addiction is controlled by creating awareness among the people and also by treating them to overcome it.Multiplex network is used to study the dynamics of addiction.Alcoholism spreads over the physical contact layer and follows the SISRS process whereas human awareness spreads over the virtual contact layer and follows the UAU process.Based on the Microscopic Markov Chain Approach competing dynamics of spreading of alcohol addiction and human awareness diffusion are studied.Necessary conditions for the existence of an alcohol-free population are found.An optimal control problem using a suitable cost index is formulated to reduce the alcohol addicts and the optimal control strategy using Pontryagin’s Minimum Principle is determined.Numerical results are developed to find the effect of various parameters and to analyze the effects of different control strategies.The results obtained from this model are closer to the data collected in the National Survey of Drug Use and Health(NSDUH)from 2002 to 2018. 展开更多
关键词 Alcohol spreading information diffusion Microscopic Markov Chain Approach optimal control
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