Brain ischemia is one of the major causes of mortality and physical disability in recent years. In order to find out an effective method to cure the disease, many researches on brain ischemia mechanism have been done....Brain ischemia is one of the major causes of mortality and physical disability in recent years. In order to find out an effective method to cure the disease, many researches on brain ischemia mechanism have been done. Calcium is an especially interesting factor in cell injury induced by brain ischemia. Much evidence has been obtained from the studies on nerve and other tissues, implying that Ca<sup>2+</sup> is a major initiator of ischemic cell injury. With ionsensitive microelectrodes, a marked reduction of Ca<sup>2+</sup> in extracellular fluid was de-展开更多
基金Project supported by the National Natural Science Foundation of China.
文摘Brain ischemia is one of the major causes of mortality and physical disability in recent years. In order to find out an effective method to cure the disease, many researches on brain ischemia mechanism have been done. Calcium is an especially interesting factor in cell injury induced by brain ischemia. Much evidence has been obtained from the studies on nerve and other tissues, implying that Ca<sup>2+</sup> is a major initiator of ischemic cell injury. With ionsensitive microelectrodes, a marked reduction of Ca<sup>2+</sup> in extracellular fluid was de-