To provide a computational efficient forward model with moderate accuracy for rapid 3D optical tomography in small volumes,radiative transport in the delta-P1 approximation combined with the approximation of the recip...To provide a computational efficient forward model with moderate accuracy for rapid 3D optical tomography in small volumes,radiative transport in the delta-P1 approximation combined with the approximation of the reciprocity was examined.Perturbations of optical signals caused by absorption and fluorescence heterogeneities submerged in a resin-based liquid phantom with background parameters close to rat brain tissues were measured using a recently constructed laminar optical tomography system.These measured perturbations were used to examine the theoretically calculated fluence perturbations based on the delta-P1 approximation and the reciprocity approximation.Results show that the errors between the predicted and measured data are acceptable,especially for fluorescence perturbations.展开更多
文摘To provide a computational efficient forward model with moderate accuracy for rapid 3D optical tomography in small volumes,radiative transport in the delta-P1 approximation combined with the approximation of the reciprocity was examined.Perturbations of optical signals caused by absorption and fluorescence heterogeneities submerged in a resin-based liquid phantom with background parameters close to rat brain tissues were measured using a recently constructed laminar optical tomography system.These measured perturbations were used to examine the theoretically calculated fluence perturbations based on the delta-P1 approximation and the reciprocity approximation.Results show that the errors between the predicted and measured data are acceptable,especially for fluorescence perturbations.