Breast cancer is the most common cancer and the leading cause of cancer death in women worldwide.1 Tumor-infiltrating myeloid cells(TiMs),key components of tumor microenvironment,are considered to be potential therape...Breast cancer is the most common cancer and the leading cause of cancer death in women worldwide.1 Tumor-infiltrating myeloid cells(TiMs),key components of tumor microenvironment,are considered to be potential therapeutic targets for cancer recently,2.3 however,their heterogeneity remains insufficiently characterized in different breast cancer subtypes.A more detailed TIM transcriptional atlas across breast cancer subtypes at the single-cell level is required to better understand the underlying mechanisms influencing the prognosis of breast cancer patients.展开更多
基金supported by the National Natural Science Foundation of China (No.81974418)Basic Research Project of Liaoning Province (No.JC2019002)+1 种基金Doctoral Start-up Foundation of Liaoning Province (No.2019-BS-284)Youth backbone Support Program of China Medical University (No.QGZ2018081).
文摘Breast cancer is the most common cancer and the leading cause of cancer death in women worldwide.1 Tumor-infiltrating myeloid cells(TiMs),key components of tumor microenvironment,are considered to be potential therapeutic targets for cancer recently,2.3 however,their heterogeneity remains insufficiently characterized in different breast cancer subtypes.A more detailed TIM transcriptional atlas across breast cancer subtypes at the single-cell level is required to better understand the underlying mechanisms influencing the prognosis of breast cancer patients.
